| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Max Th | Opening | % of Total
| Open Th | Open | Close | Distributor
| Estimated
|
|---|
| 1 | Spider-Man: No Way Home | - | - | - | $81,165,976 | - | $24,318,342 | 30% | - | Dec 15 | - | Sony Pictures Releasing | false |
| 2 | F9: The Fast Saga | - | - | - | $26,260,884 | 848 | $10,900,000 | 41.5% | 848 | Jun 24 | - | - | false |
| 3 | Venom: Let There Be Carnage | - | - | - | $24,600,000 | - | $8,072,269 | 32.8% | - | Oct 8 | - | Sony Pictures Releasing | false |
| 4 | Godzilla vs. Kong | - | - | - | $20,000,000 | - | $5,344,112 | 26.7% | - | Mar 25 | - | Warner Bros. | false |
| 5 | The Conjuring: The Devil Made Me Do It | - | - | - | $16,873,894 | 2,172 | $5,947,222 | 35.2% | - | Jun 2 | - | Warner Bros. | false |
| 6 | Serial (Bad) Weddings 2 | - | - | - | $15,297,489 | - | $20,938 | 0.1% | - | Dec 16 | - | - | false |
| 7 | Eternals | - | - | - | $15,296,153 | - | $5,681,151 | 37.1% | - | Nov 4 | - | Walt Disney Studios Motion Pictures | false |
| 8 | Sing 2 | - | - | - | $13,767,448 | 452 | $2,661,909 | 19.3% | - | Dec 22 | - | Universal Pictures | false |
| 9 | Cruella | - | - | - | $11,667,977 | - | $2,574,095 | 22.1% | - | May 27 | - | Walt Disney Studios Motion Pictures | false |
| 10 | Black Widow | - | - | - | $9,860,459 | - | $4,828,378 | 49% | - | Jul 8 | - | Walt Disney Studios Motion Pictures | false |
| 11 | Space Jam: A New Legacy | - | - | - | $8,300,000 | 1,704 | $3,136,908 | 37.8% | - | Jul 16 | - | Warner Bros. | false |
| 12 | Shang-Chi and the Legend of the Ten Rings | - | - | - | $7,673,365 | - | $2,287,156 | 29.8% | - | Sep 2 | - | Walt Disney Studios Motion Pictures | false |
| 13 | A Quiet Place Part II | - | - | - | $6,614,879 | - | $2,300,000 | - | - | Jun 11 | - | Paramount Pictures | true |
| 14 | No Time to Die | - | - | - | $6,169,077 | 876 | $2,389,000 | 38.7% | 876 | Sep 30 | - | Universal Pictures International (UPI) | false |
| 15 | The Unholy | - | - | - | $6,077,489 | - | $1,276,121 | 21% | - | Apr 22 | - | Sony Pictures Releasing | false |
| 16 | Ghostbusters: Afterlife | - | - | - | $6,060,812 | - | $2,304,347 | 38% | - | Nov 18 | - | Sony Pictures Releasing | false |
| 17 | Encanto | - | - | - | $5,415,326 | - | $1,488,947 | 27.5% | - | Nov 25 | - | Walt Disney Studios Motion Pictures | false |
| 18 | The Suicide Squad | - | - | - | $5,117,661 | - | $1,945,797 | 38% | - | Aug 5 | - | Warner Bros. | false |
| 19 | Dune: Part One | - | - | - | $5,012,909 | - | $1,987,214 | 39.6% | - | Oct 22 | - | Warner Bros. | false |
| 20 | The Matrix Resurrections | - | - | - | $5,011,381 | - | $71,827 | 1.4% | - | Dec 10 | - | Warner Bros. | false |
| 21 | The Forever Purge | - | - | - | $4,759,719 | - | $1,411,101 | 29.6% | - | Jul 1 | - | Universal Pictures | false |
| 22 | House of Gucci | - | - | - | $3,576,900 | 1 | $962,442 | 26.9% | - | Nov 25 | - | Universal Pictures International (UPI) | false |
| 23 | Free Guy | - | - | - | $3,448,942 | - | $771,976 | 22.4% | - | Aug 12 | - | Walt Disney Studios Motion Pictures | false |
| 24 | Halloween Kills | - | - | - | $3,444,376 | 1 | $1,284,013 | 37.3% | - | Oct 15 | - | Universal Pictures International (UPI) | false |
| 25 | The Addams Family 2 | - | - | - | $3,365,306 | - | $1,141,345 | 33.9% | - | Oct 14 | - | Universal Pictures | false |
| 26 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | - | - | - | $3,285,201 | - | $1,260,990 | 38.4% | - | Apr 22 | - | Cinépolis Distribución | false |
| 27 | The Boss Baby 2: Family Business | - | - | - | $3,279,777 | - | $1,205,990 | 36.8% | - | Jul 23 | - | Universal Pictures International (UPI) | false |
| 28 | Después de Ti | - | - | - | $3,162,778 | - | $158,721 | 5% | - | Apr 8 | - | Videocine | false |
| 29 | The Waiter | - | - | - | $3,098,685 | - | $1,040,609 | 33.6% | - | Jul 15 | - | Videocine | false |
| 30 | PAW Patrol: The Movie | - | - | - | $3,064,586 | - | $1,043,945 | 34.1% | - | Aug 20 | - | Paramount Pictures International | false |
| 31 | Jungle Cruise | - | - | - | $2,940,502 | - | $1,061,223 | 36.1% | - | Jul 29 | - | Walt Disney Studios Motion Pictures | false |
| 32 | Old | - | - | - | $2,916,755 | - | $822,266 | 28.2% | - | Jul 23 | - | Universal Pictures | false |
| 33 | Tom & Jerry | - | - | - | $2,900,000 | 794 | $372,024 | 12.8% | 794 | Feb 19 | - | Warner Bros. | false |
| 34 | Little Eggs: An African Rescue | - | - | - | $2,422,795 | - | $754,550 | 31.1% | - | Aug 12 | - | Videocine | false |
| 35 | The King's Man | - | - | - | $2,211,549 | - | $781,432 | 35.3% | - | Dec 30 | - | Walt Disney Studios Motion Pictures | false |
| 36 | The War with Grandpa | - | - | - | $2,209,872 | - | $507,117 | 22.9% | - | Apr 1 | - | Diamond Films | false |
| 37 | Mortal Kombat | - | - | - | $1,900,000 | - | $748,022 | 39.4% | - | Apr 16 | - | Warner Bros. | false |
| 38 | Don't Breathe 2 | - | - | - | $1,844,972 | - | $498,003 | 27% | - | Aug 12 | - | Sony Pictures Releasing | false |
| 39 | Peter Rabbit 2: The Runaway | - | - | - | $1,811,913 | - | $465,000 | 25.7% | - | May 14 | - | Sony Pictures Releasing | false |
| 40 | Chilangolandia | - | - | - | $1,721,856 | - | $649,409 | 37.7% | - | Sep 17 | - | Cinépolis Distribución | false |
| 41 | The Ice Road | - | - | - | $1,716,491 | - | $593,206 | 34.6% | - | Sep 9 | - | Zima Entertainment | false |
| 42 | Clifford the Big Red Dog | - | - | - | $1,711,974 | - | - | - | - | Dec 9 | - | Paramount Pictures | false |
| 43 | Resident Evil: Welcome to Raccoon City | - | - | - | $1,570,009 | - | $579,290 | 36.9% | - | Nov 26 | - | Sony Pictures Releasing | false |
| 44 | Come Play with Me | - | - | - | $1,548,495 | - | $198,134 | 12.8% | - | Mar 11 | - | Videocine | false |
| 45 | The Marksman | - | - | - | $1,511,105 | - | $419,387 | 27.8% | - | Mar 18 | - | Zima Entertainment | false |
| 46 | The Exorcism of Carmen Farias | - | - | - | $1,474,579 | - | - | - | - | May 7 | - | Cinépolis Distribución | false |
| 47 | Monster Hunter | - | - | - | $1,467,202 | - | $323,073 | 22% | - | Feb 18 | - | Sony Pictures Releasing | false |
| 48 | Malignant | - | - | - | $1,400,000 | - | $512,772 | 36.6% | - | Sep 9 | - | Warner Bros. | false |
| 49 | Ron's Gone Wrong | - | - | - | $1,380,459 | - | $433,962 | 31.4% | - | Oct 21 | - | Walt Disney Studios Motion Pictures | false |
| 50 | Wrath of Man | - | - | - | $1,326,279 | 642 | $461,054 | 34.8% | - | May 20 | - | Imagem Films | false |
| 51 | The Night House | - | - | - | $1,288,516 | - | $456,048 | 35.4% | - | Sep 23 | - | Walt Disney Studios Motion Pictures | false |
| 52 | King Richard | - | - | - | $1,281,090 | - | $440,000 | 34.3% | - | Dec 3 | - | Warner Bros. | false |
| 53 | Hitman's Wife's Bodyguard | - | - | - | $1,218,736 | - | $522,767 | 42.9% | - | Jun 17 | - | Corazón Films | false |
| 54 | Antlers | - | - | - | $1,136,828 | - | $375,466 | 33% | - | Oct 28 | - | Walt Disney Studios Motion Pictures | false |
| 55 | CODA | - | - | - | $1,133,267 | - | $453,791 | 40% | - | Sep 23 | - | Diamond Films | false |
| 56 | Spirit Untamed | - | - | - | $1,102,247 | - | $347,145 | 31.5% | - | Jun 10 | - | Universal Pictures | false |
| 57 | Half Brothers | - | - | - | $1,032,359 | - | - | - | - | May 7 | - | - | false |
| 58 | Chaos Walking | - | - | - | $989,827 | - | $262,754 | 26.5% | - | Mar 4 | - | Corazón Films | false |
| 59 | The Last Duel | - | - | - | $903,164 | - | $337,733 | 37.4% | - | Oct 14 | - | Walt Disney Studios Motion Pictures | false |
| 60 | Nobody | - | - | - | $800,000 | 528 | $325,987 | 40.7% | - | Apr 29 | - | Universal Pictures International (UPI) | false |
| 61 | Last Night in Soho | - | - | - | $793,870 | 1 | $248,015 | 31.2% | - | Oct 28 | - | Focus Features | false |
| 62 | Karem, la posesión | - | - | - | $792,795 | - | $311,748 | 39.3% | - | Dec 30 | - | Videocine | false |
| 63 | Harry Potter and the Sorcerer's Stone 2021 Re-release | - | - | - | $777,717 | - | $50,509 | 6.5% | - | Jan 14 | - | Warner Bros. | false |
| 64 | Chernobyl: Abyss | - | - | - | $766,304 | - | $311,911 | 40.7% | - | Nov 11 | - | Corazón Films | false |
| 65 | Invasion | - | - | - | $719,238 | - | $144,891 | 20.1% | - | Jan 7 | - | Corazón Films | false |
| 66 | Spiral | - | - | - | $714,048 | 510 | - | - | - | May 13 | - | Corazón Films | false |
| 67 | The Father | - | - | - | $691,488 | - | $157,551 | 22.8% | - | Apr 1 | - | Zima Entertainment | false |
| 68 | Blackpink: The Movie | - | - | - | $678,534 | - | $444,041 | 65.4% | - | Aug 5 | - | Cinépolis Distribución | false |
| 69 | Escape Room: Tournament of Champions | - | - | - | $662,830 | - | $364,668 | 55% | - | Sep 16 | - | Sony Pictures Releasing | false |
| 70 | Relic | - | - | - | $660,759 | - | $228,161 | 34.5% | - | Apr 8 | - | Tulip Pictures México | false |
| 71 | Snake Eyes | - | - | - | $655,474 | - | - | - | - | Jul 23 | - | Paramount Pictures | false |
| 72 | Candyman | - | - | - | $642,351 | 865 | $351,452 | 54.7% | 865 | Aug 27 | - | Universal Pictures | false |
| 73 | Reminiscence | - | - | - | $628,651 | - | $289,711 | 46.1% | - | Aug 20 | - | Warner Bros. | false |
| 74 | The Vault | - | - | - | $628,396 | - | $252,452 | 40.2% | - | Aug 26 | - | Zima Entertainment | false |
| 75 | Pinocchio | - | - | - | $580,969 | - | $164,306 | 28.3% | - | Mar 11 | - | Imagem Films | false |
| 76 | The Seventh Day | - | - | - | $566,163 | - | $240,550 | 42.5% | - | May 20 | - | Diamond Films | false |
| 77 | Those Who Wish Me Dead | - | - | - | $561,000 | - | $271,829 | 48.5% | - | May 14 | - | Warner Bros. | false |
| 78 | After We Fell | - | - | - | $558,016 | - | - | - | - | Sep 2 | - | Diamond Films | false |
| 79 | Ainbo | - | - | - | $545,881 | - | $214,805 | 39.4% | - | Sep 17 | - | Zima Entertainment | false |
| 80 | Dirty Clothes Are Washed at Home | - | - | - | $531,091 | - | $250,573 | 47.2% | - | May 20 | - | Warner Bros. | false |
| 81 | The Little Things | - | - | - | $485,828 | - | $178,804 | 36.8% | - | Mar 11 | - | Warner Bros. | false |
| 82 | Monster Family 2 | - | - | - | $462,066 | - | $199,384 | 43.2% | - | Oct 29 | - | Viva International Pictures | false |
| 83 | The French Dispatch | - | - | - | $405,357 | - | $112,332 | 27.7% | - | Nov 11 | - | Walt Disney Studios Motion Pictures | false |
| 84 | The Widow | - | - | - | $403,515 | - | $77,768 | 19.3% | - | Jan 28 | - | Corazón Films | false |
| 85 | Another Round | - | - | - | $372,449 | - | $120,746 | 32.4% | - | Jun 10 | - | Gussi Films | false |
| 86 | The Owners | - | - | - | $350,029 | - | $80,102 | 22.9% | - | Jan 21 | - | Zima Entertainment | false |
| 87 | The Head Hunter | - | - | - | $335,796 | - | $74,943 | 22.3% | - | Jan 7 | - | - | false |
| 88 | Black Water: Abyss | - | - | - | $332,539 | - | $169,548 | 51% | - | Sep 23 | - | Corazón Films | false |
| 89 | West Side Story | - | - | - | $326,998 | - | $141,794 | 43.4% | - | Dec 9 | - | Walt Disney Studios Motion Pictures | false |
| 90 | Rock Dog 2: Rock Around the Park | - | - | - | $307,246 | - | $170,576 | 55.5% | - | Nov 11 | - | Zima Entertainment | false |
| 91 | Ni tuyo, Ni mía | - | - | - | $306,120 | - | $162,042 | 52.9% | - | Aug 19 | - | Cinépolis Distribución | false |
| 92 | Two by Two: Overboard! | - | - | - | $280,637 | - | $107,285 | 38.2% | - | Mar 18 | - | Cinépolis Distribución | false |
| 93 | Promising Young Woman | - | - | - | $267,330 | - | $84,320 | 31.5% | - | Apr 9 | - | - | false |
| 94 | Breaking Surface | - | - | - | $250,515 | - | $135,420 | 54.1% | - | May 27 | - | Gussi Films | false |
| 95 | Nomadland | - | - | - | $206,420 | - | $38,501 | 18.7% | - | Apr 15 | - | Walt Disney Studios Motion Pictures | false |
| 96 | Cosas imposibles | - | - | - | $197,251 | - | $67,766 | 34.4% | - | Jun 17 | - | Videocine | false |
| 97 | The Captain | - | - | - | $191,797 | - | $80,190 | 41.8% | - | Feb 11 | - | - | false |
| 98 | Boss Level | - | - | - | $185,381 | - | $110,343 | 59.5% | - | May 27 | - | Zima Entertainment | false |
| 99 | Lake of Death | - | - | - | $169,437 | - | $100,542 | 59.3% | - | Jul 15 | - | Gussi Films | false |
| 100 | My Salinger Year | - | - | - | $160,995 | - | $95,196 | 59.1% | - | Jun 3 | - | Cinépolis Distribución | false |
| 101 | Raya and the Last Dragon | - | - | - | $152,425 | - | $19,370 | 12.7% | - | Mar 4 | - | Walt Disney Pictures | false |
| 102 | Sea Fever | - | - | - | $146,208 | - | $146,208 | 100% | - | Nov 11 | - | Gussi Films | false |
| 103 | Warning: Do Not Play | - | - | - | $140,761 | - | $38,622 | 27.4% | - | Feb 4 | - | Dark Side Distribution | false |
| 104 | Dreambuilders | - | - | - | $139,392 | - | $50,509 | 36.2% | - | Jan 14 | - | Zima Entertainment | false |
| 105 | Penguin Bloom | - | - | - | $138,298 | - | $138,298 | 100% | - | Apr 29 | - | Netflix | false |
| 106 | Side Effect | - | - | - | $133,358 | - | $133,358 | 100% | - | Apr 29 | - | Sony Pictures Releasing | false |
| 107 | In the Heights | - | - | - | $132,000 | - | $82,287 | 62.3% | - | Jun 17 | - | Warner Bros. | false |
| 108 | Show Me the Father | - | - | - | $115,939 | - | - | - | - | Sep 30 | - | Cinépolis Distribución | false |
| 109 | The Comeback Trail | - | - | - | $115,767 | - | $115,767 | 100% | - | Jul 29 | - | Corazón Films | false |
| 110 | The Evil Next Door | - | - | - | $113,980 | - | $113,980 | 100% | - | Oct 21 | - | Cinépolis Distribución | false |
| 111 | Violet Evergarden: The Movie | - | - | - | $108,316 | - | $108,316 | 100% | - | Apr 1 | - | Cinépolis Distribución | false |
| 112 | The Lord of the Rings: The Fellowship of the Ring 2021 Re-release | - | - | - | $104,160 | - | $104,160 | 100% | - | Apr 8 | - | Warner Bros. | false |
| 113 | Cry Macho | - | - | - | $94,000 | - | $59,945 | 63.8% | - | Sep 17 | - | Warner Bros. | false |
| 114 | Fatima | - | - | - | $93,472 | - | $39,386 | 42.1% | - | Oct 7 | - | Diamond Films | false |
| 115 | All That Is Invisible | - | - | - | $80,703 | - | $80,703 | 100% | - | Apr 22 | - | Cinépolis Distribución | false |
| 116 | Fate/stay night [Heaven's Feel] III. spring song | - | - | - | $77,320 | - | $77,320 | 100% | - | Mar 11 | - | Cinépolis Distribución | false |
| 117 | Skyfire | - | - | - | $69,379 | - | $69,379 | 100% | - | Oct 21 | - | Gussi Films | false |
| 118 | Lamb | - | - | - | $63,324 | - | $63,324 | 100% | - | Dec 30 | - | Cine Canibal | false |
| 119 | The Lord of the Rings: The Return of the King 2021 Re-release | - | - | - | $59,520 | - | $59,520 | 100% | - | Apr 8 | - | Warner Bros. | false |
| 120 | Wild Mountain Thyme | - | - | - | $47,949 | - | $47,949 | 100% | - | Feb 25 | - | Corazón Films | false |
| 121 | Bigfoot Family | - | - | - | $47,623 | - | $47,623 | 100% | - | Feb 11 | - | Zima Entertainment | false |
| 122 | Harry Potter and the Deathly Hallows: Part 1 2021 Re-release | - | - | - | $44,240 | - | $44,240 | 100% | - | Jan 28 | - | Warner Bros. | false |
| 123 | Harry Potter and the Goblet of Fire 2021 Re-release | - | - | - | $42,124 | - | $42,124 | 100% | - | Jan 21 | - | Warner Bros. | false |
| 124 | Vivo | - | - | - | $38,694 | - | $38,694 | 100% | - | Nov 26 | - | Bosco Films | false |
| 125 | 10 Things We Should Do Before We Break Up | - | - | - | $38,362 | - | $38,362 | 100% | - | Mar 4 | - | Dark Side Distribution | false |
| 126 | I Carry You with Me | - | - | - | $26,389 | - | $26,389 | 100% | - | Jul 8 | - | Sony Pictures Releasing | false |
| 127 | Los lobos | - | - | - | $26,086 | - | $26,061 | 99.9% | - | Jun 10 | - | Manticora Distribucion | false |
| 128 | Harry Potter and the Prisoner of Azkaban 2021 Re-release | - | - | - | $24,638 | - | $24,638 | 100% | - | Jan 14 | - | Warner Bros. | false |
| 129 | Someone, Somewhere | - | - | - | $18,409 | - | $18,409 | 100% | - | Jul 15 | - | Cinemas Nueva Era | false |
| 130 | You're Not Alone | - | - | - | $8,519 | - | $8,519 | 100% | - | Oct 21 | - | - | false |
| 131 | Be Natural: The Untold Story of Alice Guy-Blaché | - | - | - | $2,396 | - | - | - | - | Jun 25 | - | Benuca Films | false |
