| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Spider-Man: No Way Home | - | - | - | $45,636,994 | - | $81,165,976 | Dec 15 | Sony Pictures Releasing | false |
| 2 | F9: The Fast Saga | - | - | - | $26,260,884 | 848 | $26,260,884 | Jun 24 | - | false |
| 3 | Venom: Let There Be Carnage | - | - | - | $22,706,326 | - | $24,600,000 | Oct 8 | Sony Pictures Releasing | false |
| 4 | Godzilla vs. Kong | - | - | - | $18,877,736 | - | $20,000,000 | Mar 25 | Warner Bros. | false |
| 5 | The Conjuring: The Devil Made Me Do It | - | - | - | $16,217,546 | 2,172 | $16,873,894 | Jun 2 | Warner Bros. | false |
| 7 | Serial (Bad) Weddings 2 | - | - | - | $15,294,670 | - | $15,297,489 | Dec 16 | - | false |
| 6 | Eternals | - | - | - | $15,295,748 | - | $15,296,153 | Nov 4 | Walt Disney Studios Motion Pictures | false |
| 139 | The Secret Life of Pets 2 | - | - | - | $310 | 904 | $14,940,879 | Aug 9 | Universal Pictures International (UPI) | false |
| 19 | Sing 2 | - | - | - | $3,799,429 | 452 | $13,767,448 | Dec 22 | Universal Pictures | false |
| 8 | Cruella | - | - | - | $11,282,248 | - | $11,667,977 | May 27 | Walt Disney Studios Motion Pictures | false |
| 9 | Black Widow | - | - | - | $9,860,459 | - | $9,860,459 | Jul 8 | Walt Disney Studios Motion Pictures | false |
| 138 | Dolittle | - | - | - | $746 | 929 | $9,313,238 | Jan 31 | Universal Pictures International (UPI) | false |
| 10 | Space Jam: A New Legacy | - | - | - | $8,300,000 | 1,704 | $8,300,000 | Jul 16 | Warner Bros. | false |
| 11 | Shang-Chi and the Legend of the Ten Rings | - | - | - | $7,422,309 | - | $7,673,365 | Sep 2 | Walt Disney Studios Motion Pictures | false |
| 33 | A Quiet Place Part II | - | - | - | $2,300,000 | - | $6,614,879 | Jun 11 | Paramount Pictures | true |
| 12 | No Time to Die | - | - | - | $6,169,077 | 876 | $6,169,077 | Sep 30 | Universal Pictures International (UPI) | false |
| 13 | The Unholy | - | - | - | $6,077,489 | - | $6,077,489 | Apr 22 | Sony Pictures Releasing | false |
| 14 | Ghostbusters: Afterlife | - | - | - | $6,060,812 | - | $6,060,812 | Nov 18 | Sony Pictures Releasing | false |
| 16 | Encanto | - | - | - | $5,067,049 | - | $5,415,326 | Nov 25 | Walt Disney Studios Motion Pictures | false |
| 15 | The Suicide Squad | - | - | - | $5,117,661 | - | $5,117,661 | Aug 5 | Warner Bros. | false |
| 17 | Dune | - | - | - | $5,012,909 | - | $5,012,909 | Oct 22 | Warner Bros. | false |
| 34 | The Matrix Resurrections | - | - | - | $2,245,560 | - | $5,011,381 | Dec 10 | Warner Bros. | false |
| 37 | Wonder Woman 1984 | - | - | - | $1,874,616 | - | $4,959,500 | Dec 16 | Warner Bros. | false |
| 18 | The Forever Purge | - | - | - | $4,759,719 | - | $4,759,719 | Jul 1 | Universal Pictures | false |
| 40 | The Croods: A New Age | - | - | - | $1,779,844 | - | $4,111,093 | Dec 11 | Universal Pictures International (UPI) | false |
| 70 | Greenland | - | - | - | $569,849 | - | $3,619,564 | Nov 19 | Diamond Films | false |
| 25 | House of Gucci | - | - | - | $3,258,741 | 1 | $3,576,900 | Nov 25 | Universal Pictures International (UPI) | false |
| 20 | Free Guy | - | - | - | $3,448,942 | - | $3,448,942 | Aug 12 | Walt Disney Studios Motion Pictures | false |
| 22 | Halloween Kills | - | - | - | $3,322,945 | 1 | $3,444,376 | Oct 15 | Universal Pictures International (UPI) | false |
| 21 | The Addams Family 2 | - | - | - | $3,365,306 | - | $3,365,306 | Oct 14 | Universal Pictures | false |
| 23 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | - | - | - | $3,285,201 | - | $3,285,201 | Apr 22 | Cinépolis Distribución | false |
| 24 | The Boss Baby 2: Family Business | - | - | - | $3,279,777 | - | $3,279,777 | Jul 23 | Universal Pictures International (UPI) | false |
| 26 | Después de Ti | - | - | - | $3,162,778 | - | $3,162,778 | Apr 8 | Videocine | false |
| 27 | The Waiter | - | - | - | $3,098,685 | - | $3,098,685 | Jul 15 | Videocine | false |
| 28 | PAW Patrol: The Movie | - | - | - | $3,064,586 | - | $3,064,586 | Aug 20 | Paramount Pictures International | false |
| 29 | Jungle Cruise | - | - | - | $2,940,502 | - | $2,940,502 | Jul 29 | Walt Disney Studios Motion Pictures | false |
| 30 | Old | - | - | - | $2,916,755 | - | $2,916,755 | Jul 23 | Universal Pictures | false |
| 31 | Tom & Jerry | - | - | - | $2,900,000 | 794 | $2,900,000 | Feb 19 | Warner Bros. | false |
| 32 | Little Eggs: An African Rescue | - | - | - | $2,422,795 | - | $2,422,795 | Aug 12 | Videocine | false |
| 35 | The War with Grandpa | - | - | - | $2,209,872 | - | $2,209,872 | Apr 1 | Diamond Films | false |
| 36 | Mortal Kombat | - | - | - | $1,900,000 | - | $1,900,000 | Apr 16 | Warner Bros. | false |
| 38 | Don't Breathe 2 | - | - | - | $1,844,972 | - | $1,844,972 | Aug 12 | Sony Pictures Releasing | false |
| 39 | Peter Rabbit 2: The Runaway | - | - | - | $1,811,913 | - | $1,811,913 | May 14 | Sony Pictures Releasing | false |
| 41 | Chilangolandia | - | - | - | $1,721,856 | - | $1,721,856 | Sep 17 | Cinépolis Distribución | false |
| 42 | The Ice Road | - | - | - | $1,716,491 | - | $1,716,491 | Sep 9 | Zima Entertainment | false |
| 136 | Peninsula | - | - | - | $4,662 | - | $1,617,806 | Nov 5 | - | false |
| 43 | Resident Evil: Welcome to Raccoon City | - | - | - | $1,570,009 | - | $1,570,009 | Nov 26 | Sony Pictures Releasing | false |
| 44 | Come Play with Me | - | - | - | $1,548,495 | - | $1,548,495 | Mar 11 | Videocine | false |
| 45 | The Marksman | - | - | - | $1,511,105 | - | $1,511,105 | Mar 18 | Zima Entertainment | false |
| 61 | The Exorcism of Carmen Farias | - | - | - | $729,565 | - | $1,474,579 | May 7 | Cinépolis Distribución | false |
| 46 | Monster Hunter | - | - | - | $1,467,202 | - | $1,467,202 | Feb 18 | Sony Pictures Releasing | false |
| 47 | Malignant | - | - | - | $1,400,000 | - | $1,400,000 | Sep 9 | Warner Bros. | false |
| 48 | Ron's Gone Wrong | - | - | - | $1,380,459 | - | $1,380,459 | Oct 21 | Walt Disney Studios Motion Pictures | false |
| 49 | Wrath of Man | - | - | - | $1,326,279 | 642 | $1,326,279 | May 20 | - | false |
| 50 | The Night House | - | - | - | $1,288,516 | - | $1,288,516 | Sep 23 | Walt Disney Studios Motion Pictures | false |
| 51 | King Richard | - | - | - | $1,232,379 | - | $1,281,090 | Dec 3 | Warner Bros. | false |
| 52 | Hitman's Wife's Bodyguard | - | - | - | $1,218,736 | - | $1,218,736 | Jun 17 | - | false |
| 53 | Antlers | - | - | - | $1,136,828 | - | $1,136,828 | Oct 28 | Walt Disney Studios Motion Pictures | false |
| 55 | CODA | - | - | - | $1,052,792 | - | $1,133,267 | Sep 23 | Diamond Films | false |
| 54 | Spirit Untamed | - | - | - | $1,102,247 | - | $1,102,247 | Jun 10 | Universal Pictures | false |
| 78 | Half Brothers | - | - | - | $458,497 | - | $1,032,359 | May 7 | - | false |
| 56 | Chaos Walking | - | - | - | $989,827 | - | $989,827 | Mar 4 | - | false |
| 57 | The Last Duel | - | - | - | $903,164 | - | $903,164 | Oct 14 | Walt Disney Studios Motion Pictures | false |
| 58 | Nobody | - | - | - | $800,000 | 528 | $800,000 | Apr 29 | Universal Pictures International (UPI) | false |
| 73 | Last Night in Soho | - | - | - | $550,547 | 1 | $793,870 | Oct 28 | Focus Features | false |
| 59 | Harry Potter and the Sorcerer's Stone 2021 Re-release | - | - | - | $777,717 | - | $777,717 | Jan 14 | Warner Bros. | false |
| 60 | Chernobyl: Abyss | - | - | - | $766,304 | - | $766,304 | Nov 11 | - | false |
| 62 | Invasion | - | - | - | $719,238 | - | $719,238 | Jan 7 | - | false |
| 95 | Spiral | - | - | - | $245,069 | 510 | $714,048 | May 13 | - | false |
| 63 | The Father | - | - | - | $691,488 | - | $691,488 | Apr 1 | Zima Entertainment | false |
| 79 | Blackpink: The Movie | - | - | - | $444,041 | - | $678,534 | Aug 5 | Cinépolis Distribución | false |
| 68 | Escape Room: Tournament of Champions | - | - | - | $593,419 | - | $662,830 | Sep 16 | Sony Pictures Releasing | false |
| 64 | Relic | - | - | - | $660,759 | - | $660,759 | Apr 8 | Tulip Pictures | false |
| 65 | Candyman | - | - | - | $642,351 | 865 | $642,351 | Aug 27 | Universal Pictures | false |
| 66 | Reminiscence | - | - | - | $628,651 | - | $628,651 | Aug 20 | Warner Bros. | false |
| 67 | The Vault | - | - | - | $628,396 | - | $628,396 | Aug 26 | Zima Entertainment | false |
| 69 | Pinocchio | - | - | - | $580,969 | - | $580,969 | Mar 11 | - | false |
| 71 | The Seventh Day | - | - | - | $566,163 | - | $566,163 | May 20 | Diamond Films | false |
| 72 | Those Who Wish Me Dead | - | - | - | $561,000 | - | $561,000 | May 14 | Warner Bros. | false |
| 105 | After We Fell | - | - | - | $140,761 | - | $558,016 | Sep 2 | Diamond Films | false |
| 74 | Ainbo | - | - | - | $545,881 | - | $545,881 | Sep 17 | Zima Entertainment | false |
| 83 | Tell Me When | - | - | - | $368,759 | - | $539,584 | Dec 24 | Cinépolis Distribución | false |
| 75 | Dirty Clothes Are Washed at Home | - | - | - | $531,091 | - | $531,091 | May 20 | Warner Bros. | false |
| 76 | The Little Things | - | - | - | $485,828 | - | $485,828 | Mar 11 | Warner Bros. | false |
| 77 | Monster Family 2 | - | - | - | $462,066 | - | $462,066 | Oct 29 | Viva International Pictures | false |
| 81 | The French Dispatch | - | - | - | $382,629 | - | $405,357 | Nov 11 | Walt Disney Studios Motion Pictures | false |
| 80 | The Widow | - | - | - | $403,515 | - | $403,515 | Jan 28 | - | false |
| 82 | Another Round | - | - | - | $372,449 | - | $372,449 | Jun 10 | - | false |
| 84 | Come Away | - | - | - | $355,453 | - | $355,453 | Dec 31 | Zima Entertainment | false |
| 85 | The Owners | - | - | - | $350,029 | - | $350,029 | Jan 21 | Zima Entertainment | false |
| 86 | Espiral | - | - | - | $337,270 | 20 | $337,270 | Sep 11 | - | false |
| 87 | The Head Hunter | - | - | - | $335,796 | - | $335,796 | Jan 7 | - | false |
| 88 | Black Water: Abyss | - | - | - | $332,539 | - | $332,539 | Sep 23 | - | false |
| 92 | West Side Story | - | - | - | $278,139 | - | $326,998 | Dec 9 | Walt Disney Studios Motion Pictures | false |
| 137 | Against the Devil | - | - | - | $2,170 | - | $321,551 | Jul 3 | - | false |
| 133 | The Tunnel | - | - | - | $10,798 | - | $309,766 | Dec 3 | - | false |
| 89 | Rock Dog 2: Rock Around the Park | - | - | - | $307,246 | - | $307,246 | Nov 11 | Zima Entertainment | false |
| 90 | Ni tuyo, Ni mía | - | - | - | $306,120 | - | $306,120 | Aug 19 | Cinépolis Distribución | false |
| 91 | Two by Two: Overboard! | - | - | - | $280,637 | - | $280,637 | Mar 18 | Cinépolis Distribución | false |
| 93 | Promising Young Woman | - | - | - | $267,330 | - | $267,330 | Apr 9 | - | false |
| 94 | Breaking Surface | - | - | - | $250,515 | - | $250,515 | May 27 | - | false |
| 96 | Nomadland | - | - | - | $206,420 | - | $206,420 | Apr 15 | Walt Disney Studios Motion Pictures | false |
| 97 | Cosas imposibles | - | - | - | $197,251 | - | $197,251 | Jun 17 | Videocine | false |
| 98 | The Captain | - | - | - | $191,797 | - | $191,797 | Feb 11 | - | false |
| 99 | Boss Level | - | - | - | $185,381 | - | $185,381 | May 27 | Zima Entertainment | false |
| 100 | Lake of Death | - | - | - | $169,437 | - | $169,437 | Jul 15 | - | false |
| 101 | My Salinger Year | - | - | - | $155,985 | - | $160,995 | Jun 3 | Cinépolis Distribución | false |
| 102 | Raya and the Last Dragon | - | - | - | $152,425 | - | $152,425 | Mar 4 | Walt Disney Pictures | false |
| 103 | Sea Fever | - | - | - | $146,208 | - | $146,208 | Nov 11 | - | false |
| 104 | Warning: Do Not Play | - | - | - | $140,761 | - | $140,761 | Feb 4 | Dark Side Distribution | false |
| 106 | Dreambuilders | - | - | - | $139,392 | - | $139,392 | Jan 14 | Zima Entertainment | false |
| 107 | Penguin Bloom | - | - | - | $138,298 | - | $138,298 | Apr 29 | Netflix | false |
| 108 | Side Effect | - | - | - | $133,358 | - | $133,358 | Apr 29 | Sony Pictures Releasing | false |
| 109 | In the Heights | - | - | - | $132,000 | - | $132,000 | Jun 17 | Warner Bros. | false |
| 134 | The Soul Conductor | - | - | - | $9,757 | - | $119,909 | Aug 14 | - | false |
| 128 | Show Me the Father | - | - | - | $35,646 | - | $115,939 | Sep 30 | Cinépolis Distribución | false |
| 110 | The Comeback Trail | - | - | - | $115,767 | - | $115,767 | Jul 29 | - | false |
| 111 | The Evil Next Door | - | - | - | $113,980 | - | $113,980 | Oct 21 | Cinépolis Distribución | false |
| 112 | No, porque me enamoro | - | - | - | $108,662 | - | $108,662 | Oct 30 | Videocine | false |
| 113 | Violet Evergarden: The Movie | - | - | - | $108,316 | - | $108,316 | Apr 1 | Cinépolis Distribución | false |
| 114 | The Lord of the Rings: The Fellowship of the Ring 2021 Re-release | - | - | - | $104,160 | - | $104,160 | Apr 8 | Warner Bros. | false |
| 115 | Cry Macho | - | - | - | $94,000 | - | $94,000 | Sep 17 | Warner Bros. | false |
| 116 | Fatima | - | - | - | $89,960 | - | $93,472 | Oct 7 | Diamond Films | false |
| 117 | All That Is Invisible | - | - | - | $80,703 | - | $80,703 | Apr 22 | Cinépolis Distribución | false |
| 118 | Fate/stay night [Heaven's Feel] III. spring song | - | - | - | $77,320 | - | $77,320 | Mar 11 | Cinépolis Distribución | false |
| 119 | Skyfire | - | - | - | $69,379 | - | $69,379 | Oct 21 | - | false |
| 120 | The 100 Candles Game | - | - | - | $64,951 | - | $64,951 | Dec 31 | Dark Side Distribution | false |
| 121 | The Lord of the Rings: The Return of the King 2021 Re-release | - | - | - | $59,520 | - | $59,520 | Apr 8 | Warner Bros. | false |
| 122 | Wild Mountain Thyme | - | - | - | $47,949 | - | $47,949 | Feb 25 | - | false |
| 123 | Bigfoot Family | - | - | - | $47,623 | - | $47,623 | Feb 11 | Zima Entertainment | false |
| 124 | Harry Potter and the Deathly Hallows: Part 1 2021 Re-release | - | - | - | $44,240 | - | $44,240 | Jan 28 | Warner Bros. | false |
| 125 | Harry Potter and the Goblet of Fire 2021 Re-release | - | - | - | $42,124 | - | $42,124 | Jan 21 | Warner Bros. | false |
| 126 | Vivo | - | - | - | $38,694 | - | $38,694 | Nov 26 | Bosco Films | false |
| 127 | 10 Things We Should Do Before We Break Up | - | - | - | $38,362 | - | $38,362 | Mar 4 | Dark Side Distribution | false |
| 129 | I Carry You with Me | - | - | - | $26,389 | - | $26,389 | Jul 8 | Sony Pictures Releasing | false |
| 130 | Los lobos | - | - | - | $26,061 | - | $26,086 | Jun 10 | Manticora Distribucion | false |
| 131 | Harry Potter and the Prisoner of Azkaban 2021 Re-release | - | - | - | $24,638 | - | $24,638 | Jan 14 | Warner Bros. | false |
| 132 | Someone, Somewhere | - | - | - | $18,409 | - | $18,409 | Jul 15 | Cinemas Nueva Era | false |
| 135 | You're Not Alone | - | - | - | $8,519 | - | $8,519 | Oct 21 | - | false |
