| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Avatar | - | - | - | $1,938,765 | 22 | $2,916,247 | Dec 17 | Tatrafilm | false |
| 2 | Shrek Forever After | - | - | - | $1,570,982 | 20 | $1,570,982 | Jul 15 | Tatrafilm | false |
| 3 | Alice in Wonderland | - | - | - | $1,093,280 | 17 | $1,093,280 | Mar 11 | Saturn Enternainment | false |
| 4 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $909,060 | 21 | $1,005,195 | Nov 18 | Continental Film | false |
| 5 | Clash of the Titans | - | - | - | $655,170 | 17 | $655,170 | Apr 15 | Continental Film | false |
| 6 | Inception | - | - | - | $603,440 | 16 | $603,440 | Jul 22 | Continental Film | false |
| 7 | The Twilight Saga: Eclipse | - | - | - | $578,598 | 17 | $578,598 | Jul 1 | SPI International | false |
| 8 | Román pro muze | - | - | - | $514,112 | 21 | $514,112 | Sep 23 | - | false |
| 9 | Toy Story 3 | - | - | - | $483,478 | 18 | $483,478 | Aug 19 | Saturn Enternainment | false |
| 10 | Despicable Me | - | - | - | $481,779 | 22 | $481,779 | Oct 21 | Tatrafilm | false |
| 11 | How to Train Your Dragon | - | - | - | $452,523 | 22 | $467,953 | Mar 25 | Tatrafilm | false |
| 12 | Step Up 3D | - | - | - | $398,433 | 20 | $398,433 | Sep 2 | SPI International | false |
| 13 | Kajínek | - | - | - | $388,364 | 18 | $388,364 | Aug 12 | - | false |
| 14 | Sex and the City 2 | - | - | - | $380,618 | 16 | $380,618 | May 27 | Continental Film | false |
| 15 | Sherlock Holmes | - | - | - | $379,976 | 14 | $379,976 | Dec 31 | Continental Film | false |
| 16 | Prince of Persia: The Sands of Time | - | - | - | $290,238 | 15 | $290,238 | May 20 | Saturn Enternainment | false |
| 17 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $281,772 | 16 | $281,772 | Aug 5 | Continental Film | false |
| 18 | Eat Pray Love | - | - | - | $279,186 | 15 | $279,186 | Oct 21 | Sony Pictures Releasing | false |
| 19 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $249,842 | 14 | $249,842 | Oct 7 | Continental Film | false |
| 20 | Saw 3D | - | - | - | $242,080 | 15 | $292,098 | Oct 28 | Continental Film | false |
| 21 | Women in Temptation | - | - | - | $236,191 | 13 | $304,100 | Jun 10 | - | false |
| 22 | Resident Evil: Afterlife | - | - | - | $221,284 | 15 | $221,284 | Sep 23 | Sony Pictures Releasing | false |
| 23 | The Princess and the Frog | - | - | - | $208,840 | 12 | $208,840 | Feb 18 | Saturn Enternainment | false |
| 24 | Iron Man 2 | - | - | - | $202,047 | 16 | $202,047 | Apr 29 | Tatrafilm | false |
| 25 | The Bounty Hunter | - | - | - | $197,442 | 9 | $197,442 | Apr 1 | Sony Pictures Releasing | false |
| 26 | Robin Hood | - | - | - | $189,364 | 16 | $189,364 | May 13 | Tatrafilm | false |
| 27 | The Last Airbender | - | - | - | $188,675 | 19 | $188,675 | Aug 26 | Tatrafilm | false |
| 28 | Alpha and Omega | - | - | - | $187,811 | 15 | $187,811 | Nov 4 | - | false |
| 29 | Deadline | - | - | - | $181,695 | 10 | $181,695 | Nov 4 | Continental Film | false |
| 30 | The Chronicles of Narnia: The Voyage of the Dawn Treader | - | - | - | $180,722 | 21 | $334,282 | Dec 9 | Tatrafilm | false |
| 31 | Legenda o Lietajúcom Cypriánovi | - | - | - | $169,797 | 15 | $169,797 | Jul 29 | SPI International | false |
| 32 | Alvin and the Chipmunks: The Squeakquel | - | - | - | $165,999 | 11 | $242,887 | Dec 24 | Tatrafilm | false |
| 33 | Salt | - | - | - | $151,522 | 15 | $151,522 | Aug 12 | Sony Pictures Releasing | false |
| 34 | Doktor od jezera hrochu | - | - | - | $149,222 | 12 | $149,222 | Mar 4 | SPI International | false |
| 35 | Shutter Island | - | - | - | $147,446 | 12 | $147,446 | Feb 25 | Tatrafilm | false |
| 36 | Valentine's Day | - | - | - | $139,263 | 10 | $139,275 | Feb 18 | Continental Film | false |
| 37 | Law Abiding Citizen | - | - | - | $139,155 | 10 | $139,155 | Jan 7 | - | false |
| 38 | The Sorcerer's Apprentice | - | - | - | $131,528 | 17 | $131,528 | Sep 16 | Saturn Enternainment | false |
| 39 | Grown Ups | - | - | - | $127,825 | 8 | $127,825 | Aug 26 | Sony Pictures Releasing | false |
| 40 | Garfield's Pet Force | - | - | - | $119,671 | 15 | $137,470 | Jun 3 | - | false |
| 41 | The Social Network | - | - | - | $106,945 | 13 | $124,007 | Nov 4 | Sony Pictures Releasing | false |
| 42 | The Expendables | - | - | - | $105,265 | 14 | $112,730 | Sep 30 | Continental Film | false |
| 43 | Tangled | - | - | - | $96,241 | 19 | $895,433 | Dec 19 | Saturn Enternainment | false |
| 44 | Wall Street: Money Never Sleeps | - | - | - | $93,572 | 10 | $93,572 | Sep 30 | Tatrafilm | false |
| 45 | Megamind | - | - | - | $90,517 | 19 | $90,517 | Dec 2 | Tatrafilm | false |
| 46 | The Back-up Plan | - | - | - | $90,272 | 12 | $90,272 | Jun 17 | Sony Pictures Releasing | false |
| 47 | StreetDance 2 | - | - | - | $81,292 | 15 | $81,292 | May 27 | Tatrafilm | false |
| 48 | It's Complicated | - | - | - | $80,787 | 8 | $132,094 | Jan 21 | Tatrafilm | false |
| 49 | The Book of Eli | - | - | - | $76,762 | 9 | $76,762 | Mar 4 | Sony Pictures Releasing | false |
| 50 | Knight and Day Original Release | - | - | - | $68,759 | 12 | $68,759 | Jul 29 | Tatrafilm | false |
| 51 | Did You Hear About the Morgans? | - | - | - | $68,598 | 9 | $68,598 | Feb 4 | Sony Pictures Releasing | false |
| 52 | The Wolfman | - | - | - | $63,495 | 10 | $63,495 | Feb 18 | Tatrafilm | false |
| 53 | Kawasaki's Rose | - | - | - | $62,844 | 11 | $62,844 | Feb 11 | - | false |
| 54 | The Other Guys | - | - | - | $55,977 | 9 | $55,977 | Oct 7 | Sony Pictures Releasing | false |
| 55 | The Karate Kid | - | - | - | $54,707 | 15 | $62,048 | Sep 9 | Sony Pictures Releasing | false |
| 56 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $54,477 | 10 | $54,477 | Feb 11 | Tatrafilm | false |
| 57 | Couples Retreat | - | - | - | $49,639 | 7 | $49,639 | Dec 31 | Tatrafilm | false |
| 58 | Legion | - | - | - | $49,302 | 9 | $49,302 | Mar 18 | Sony Pictures Releasing | false |
| 59 | RED | - | - | - | $48,416 | 15 | $48,416 | Nov 26 | - | false |
| 60 | Desert Flower 2009 Re-release | - | - | - | $47,141 | 13 | $113,579 | Jun 17 | Continental Film | false |
| 61 | Heartbreaker | - | - | - | $39,819 | 8 | $39,819 | Oct 14 | - | false |
| 62 | The Twilight Saga: New Moon | - | - | - | $38,326 | 15 | $603,395 | Nov 26 | SPI International | false |
| 63 | Planet 51 | - | - | - | $37,709 | 13 | $104,623 | Jan 14 | - | false |
| 64 | Brothers | - | - | - | $33,396 | 10 | $33,396 | Apr 8 | - | false |
| 65 | Up in the Air | - | - | - | $25,588 | 9 | $25,588 | Jan 28 | Tatrafilm | false |
| 66 | Remember Me | - | - | - | $24,090 | 8 | $24,090 | May 6 | Continental Film | false |
| 67 | Machete | - | - | - | $22,002 | 10 | $22,002 | Nov 11 | - | false |
| 68 | Killers | - | - | - | $21,567 | 12 | $21,567 | Aug 26 | - | false |
| 69 | Paranormal Activity 2 | - | - | - | $21,141 | 9 | $21,141 | Dec 16 | Tatrafilm | false |
| 70 | Edge of Darkness | - | - | - | $20,754 | 12 | $45,644 | Apr 22 | - | false |
| 71 | Predators | - | - | - | $18,862 | 10 | $63,605 | Jul 8 | Tatrafilm | false |
| 72 | Life as We Know It | - | - | - | $18,438 | 7 | $28,162 | Dec 9 | Continental Film | false |
| 73 | The Fourth Kind | - | - | - | $14,703 | 8 | $38,454 | Jan 21 | - | false |
| 74 | Going the Distance | - | - | - | $12,537 | 8 | $12,537 | Sep 9 | Continental Film | false |
| 75 | The Imaginarium of Doctor Parnassus | - | - | - | $11,245 | 8 | $41,555 | Mar 25 | Continental Film | false |
| 76 | Daybreakers | - | - | - | $11,048 | 6 | $11,048 | May 6 | - | false |
| 77 | The Ghost Writer | - | - | - | $9,477 | 8 | $9,477 | Oct 7 | SPI International | false |
| 78 | Zombieland | - | - | - | $2,036 | 9 | $36,974 | Dec 10 | Sony Pictures Releasing | false |
