| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Max Th | Opening | % of Total
| Open Th | Open | Close | Distributor
| Estimated
|
|---|
| 1 | Spider-Man 3 | - | - | - | $5,216,902 | - | - | - | - | May 2 | - | - | false |
| 2 | Harry Potter and the Order of the Phoenix | - | - | - | $3,275,264 | - | - | - | - | Jul 11 | - | - | false |
| 3 | Transformers | - | - | - | $2,486,545 | - | - | - | - | Jun 28 | - | - | false |
| 4 | Pirates of the Caribbean: At World's End | - | - | - | $2,138,791 | - | - | - | - | May 23 | - | - | false |
| 5 | Fantastic Four: Rise of the Silver Surfer | - | - | - | $1,844,603 | - | - | - | - | Jun 13 | - | - | false |
| 6 | Rush Hour 3 | - | - | - | $1,827,826 | - | - | - | - | Aug 18 | - | - | false |
| 7 | Live Free or Die Hard | - | - | - | $1,756,831 | - | - | - | - | Jul 4 | - | - | false |
| 8 | Mr. Bean's Holiday | - | - | - | $1,572,348 | - | - | - | - | Mar 28 | - | - | false |
| 9 | National Treasure: Book of Secrets | - | - | - | $1,512,975 | - | - | - | - | Dec 21 | - | - | false |
| 10 | I Am Legend | - | - | - | $1,381,969 | - | - | - | - | Dec 12 | - | - | false |
| 11 | 300 | - | - | - | $1,357,394 | - | - | - | - | Mar 16 | - | - | false |
| 12 | Ghost Rider | - | - | - | $1,326,850 | - | - | - | - | Feb 14 | - | - | false |
| 13 | The Bourne Ultimatum | - | - | - | $1,224,974 | - | - | - | - | Aug 10 | - | - | false |
| 14 | Ocean's Thirteen | - | - | - | $747,062 | - | - | - | - | Jun 6 | - | - | false |
| 15 | Shrek the Third | - | - | - | $676,110 | - | - | - | - | Jun 14 | - | - | false |
| 16 | Beowulf | - | - | - | $657,798 | - | - | - | - | Nov 14 | - | - | false |
| 17 | Ratatouille | - | - | - | $629,399 | - | - | - | - | Aug 15 | - | - | false |
| 18 | Enchanted | - | - | - | $530,896 | - | - | - | - | Nov 21 | - | - | false |
| 19 | The Simpsons Movie | - | - | - | $523,701 | - | - | - | - | Jul 25 | - | - | false |
| 20 | Hitman | - | - | - | $464,201 | - | - | - | - | Nov 23 | - | - | false |
| 21 | The Kingdom | - | - | - | $444,672 | - | - | - | - | Nov 28 | - | - | false |
| 22 | Bee Movie | - | - | - | $383,992 | - | - | - | - | Dec 19 | - | - | false |
| 23 | The Game Plan | - | - | - | $381,843 | - | - | - | - | Nov 8 | - | - | false |
| 24 | The Invasion | - | - | - | $333,298 | - | - | - | - | Aug 29 | - | - | false |
| 25 | The Reaping | - | - | - | $314,255 | - | - | - | - | Apr 11 | - | - | false |
| 26 | The Brave One | - | - | - | $308,246 | - | - | - | - | Sep 12 | - | - | false |
| 27 | The Seeker: The Dark Is Rising | - | - | - | $306,652 | - | - | - | - | Oct 24 | - | - | false |
| 28 | Shooter | - | - | - | $304,371 | - | - | - | - | Apr 18 | - | - | false |
| 29 | Pathfinder | - | - | - | $304,111 | - | - | - | - | Jan 10 | - | - | false |
| 30 | Wild Hogs | - | - | - | $297,475 | - | - | - | - | Apr 13 | - | - | false |
| 31 | Stardust | - | - | - | $289,079 | - | - | - | - | Nov 9 | - | - | false |
| 32 | Disturbia | - | - | - | $273,637 | - | - | - | - | Sep 5 | - | - | false |
| 33 | No Reservations | - | - | - | $269,566 | - | - | - | - | Sep 19 | - | - | false |
| 34 | Underdog | - | - | - | $256,371 | - | - | - | - | Sep 14 | - | - | false |
| 35 | Surf's Up | - | - | - | $248,404 | - | - | - | - | Aug 3 | - | - | false |
| 36 | Norbit | - | - | - | $230,553 | - | - | - | - | Apr 12 | - | - | false |
| 37 | 28 Weeks Later | - | - | - | $229,157 | - | - | - | - | May 9 | - | - | false |
| 38 | The Holiday | - | - | - | $224,379 | - | - | - | - | Feb 8 | - | - | false |
| 39 | Music and Lyrics | - | - | - | $221,709 | - | - | - | - | Feb 28 | - | - | false |
| 40 | The Pursuit of Happyness | - | - | - | $207,160 | - | - | - | - | Mar 2 | - | - | false |
| 41 | Flushed Away | - | - | - | $196,087 | - | - | - | - | Jan 3 | - | - | false |
| 42 | The Heartbreak Kid | - | - | - | $189,291 | - | - | - | - | Dec 5 | - | - | false |
| 43 | The Number 23 | - | - | - | $178,652 | - | - | - | - | May 31 | - | - | false |
| 44 | Epic Movie | - | - | - | $164,322 | - | - | - | - | Feb 7 | - | - | false |
| 45 | Lions for Lambs | - | - | - | $163,500 | - | - | - | - | Nov 7 | - | - | false |
| 46 | License to Wed | - | - | - | $162,593 | - | - | - | - | Oct 31 | - | - | false |
| 47 | Sunshine | - | - | - | $151,149 | - | - | - | - | Apr 20 | - | - | false |
| 48 | Meet the Robinsons | - | - | - | $145,696 | - | - | - | - | Mar 29 | - | - | false |
| 49 | TMNT | - | - | - | $139,929 | - | - | - | - | Apr 5 | - | - | false |
| 50 | 30 Days of Night | - | - | - | $132,431 | - | - | - | - | Dec 7 | - | - | false |
| 51 | Fred Claus | - | - | - | $89,911 | - | - | - | - | Dec 27 | - | - | false |
| 52 | Charlotte's Web | - | - | - | $86,131 | - | - | - | - | Mar 8 | - | - | false |
| 53 | Dreamgirls | - | - | - | $72,889 | - | - | - | - | Mar 15 | - | - | false |
| 54 | Lust, Caution | - | - | - | $72,726 | - | - | - | - | Oct 25 | - | - | false |
| 55 | A Good Year | - | - | - | $72,671 | - | - | - | - | Jan 24 | - | - | false |
| 56 | Flags of Our Fathers | - | - | - | $57,554 | - | - | - | - | Feb 7 | - | - | false |
| 57 | Rocky Balboa | - | - | - | $49,274 | - | - | - | - | Mar 2 | - | - | false |
| 58 | The Last Mimzy | - | - | - | $44,448 | - | - | - | - | Jun 23 | - | - | false |
| 59 | The Hitcher | - | - | - | $20,362 | - | - | - | - | Jun 22 | - | - | false |
| 60 | Saawariya | - | - | - | $11,954 | - | - | - | - | Nov 16 | - | - | false |
