| Rank | Release | Genre | Budget | Running Time | Gross | Theaters | Total Gross | Release Date | Distributor | Estimated | 
|---|
| 1 | Pirates of the Caribbean: Dead Man's Chest | - | - | - | $36,609,592 | 787 | $36,609,592 | Aug 11 | Buena Vista International | false | 
| 2 | The Da Vinci Code | - | - | - | $34,543,406 | 752 | $34,543,406 | May 19 | Sony Pictures Releasing | false | 
| 3 | Ice Age 2: The Meltdown | - | - | - | $24,248,139 | 451 | $24,248,139 | Mar 31 | 20th Century Fox International | false | 
| 4 | Captain Alatriste: The Spanish Musketeer | - | - | - | $20,900,190 | 450 | $21,215,090 | Sep 1 | 20th Century Fox International | false | 
| 5 | Cars | - | - | - | $15,867,176 | 556 | $16,342,337 | Jul 7 | Buena Vista International | false | 
| 6 | Memoirs of a Geisha | - | - | - | $14,739,365 | 240 | $14,289,365 | Jan 20 | Sony Pictures Releasing | false | 
| 7 | X-Men: The Last Stand | - | - | - | $12,132,233 | 454 | $12,315,946 | May 26 | 20th Century Fox International | false | 
| 8 | Volver | - | - | - | $12,067,236 | 239 | $12,241,181 | Mar 17 | Warner Bros. | false | 
| 9 | The Departed | - | - | - | $11,500,865 | 375 | $13,905,443 | Oct 27 | Warner Bros. | false | 
| 10 | Casino Royale | - | - | - | $11,360,331 | 500 | $12,149,464 | Nov 24 | Sony Pictures Releasing | false | 
| 11 | Eragon | - | - | - | $10,324,917 | 498 | $14,236,082 | Dec 15 | 20th Century Fox International | false | 
| 12 | Crash | - | - | - | $10,270,180 | 176 | $10,270,180 | Jan 13 | Manga Entertainment | false | 
| 13 | Superman Returns | - | - | - | $10,230,027 | 560 | $11,721,291 | Jul 12 | Warner Bros. | false | 
| 14 | Deja Vu | - | - | - | $9,419,882 | 432 | $11,083,441 | Dec 1 | Buena Vista International | false | 
| 15 | Mission: Impossible III | - | - | - | $9,190,665 | 529 | $9,190,665 | May 5 | United International Pictures | false | 
| 16 | The Illusionist | - | - | - | $9,106,618 | 206 | $12,775,508 | Nov 17 | Aurum Films | false | 
| 17 | Perfume: The Story of a Murderer | - | - | - | $8,936,244 | 309 | $9,906,765 | Nov 24 | Filmax | false | 
| 18 | Brokeback Mountain | - | - | - | $8,527,730 | 190 | $8,527,730 | Jan 20 | United International Pictures | false | 
| 19 | The Pink Panther | - | - | - | $8,477,526 | 350 | $8,477,526 | Feb 24 | 20th Century Fox International | false | 
| 20 | Pan's Labyrinth | - | - | - | $8,331,806 | 302 | $11,774,227 | Oct 11 | Warner Bros. | false | 
| 21 | The Borgia | - | - | - | $8,299,543 | 325 | $8,299,543 | Oct 6 | DeAPlaneta | false | 
| 22 | The Devil Wears Prada | - | - | - | $8,025,373 | 302 | $8,126,592 | Oct 6 | 20th Century Fox International | false | 
| 23 | Over the Hedge | - | - | - | $7,988,251 | 479 | $7,988,251 | Jun 16 | United International Pictures | false | 
| 24 | Poseidon | - | - | - | $7,614,284 | 429 | $8,550,398 | Jul 28 | Warner Bros. | false | 
| 25 | Scoop | - | - | - | $7,350,548 | 161 | $7,559,594 | Oct 27 | On Pictures | false | 
| 26 | Munich | - | - | - | $7,308,697 | 228 | $7,308,697 | Jan 27 | United International Pictures | false | 
| 27 | Inside Man | - | - | - | $7,301,916 | 256 | $7,821,983 | Apr 12 | United International Pictures | false | 
| 28 | Garfield: A Tail of Two Kitties | - | - | - | $7,267,984 | 415 | $8,584,642 | Aug 25 | 20th Century Fox International | false | 
| 29 | Flushed Away | - | - | - | $7,141,715 | 441 | $8,244,798 | Dec 1 | United International Pictures | false | 
| 30 | Saw III | - | - | - | $6,637,970 | 300 | $6,740,743 | Nov 10 | Buena Vista International | false | 
| 31 | Big Momma's House 2 | - | - | - | $6,460,617 | 300 | $6,460,617 | Jan 27 | 20th Century Fox International | false | 
| 32 | Little Man | - | - | - | $6,398,603 | 250 | $6,398,603 | Sep 15 | Sony Pictures Releasing | false | 
| 33 | Happy Feet | - | - | - | $6,261,252 | 480 | $10,057,345 | Dec 5 | Warner Bros. | false | 
| 34 | World Trade Center | - | - | - | $6,160,013 | 334 | $5,958,708 | Sep 29 | United International Pictures | false | 
| 35 | The Sentinel | - | - | - | $6,116,344 | 285 | $6,255,372 | Jul 21 | 20th Century Fox International | false | 
| 36 | The Chronicles of Narnia: The Lion, the Witch and the Wardrobe | - | - | - | $6,100,377 | 455 | $22,545,083 | Dec 7 | Buena Vista International | false | 
| 37 | Miami Vice | - | - | - | $5,793,660 | 292 | $4,417,672 | Sep 8 | United International Pictures | false | 
| 38 | Lady in the Water | - | - | - | $5,728,908 | 328 | $5,728,908 | Aug 25 | Warner Bros. | false | 
| 39 | Click | - | - | - | $5,511,461 | 324 | $5,511,461 | Sep 29 | Sony Pictures Releasing | false | 
| 40 | Monster House | - | - | - | $5,456,949 | 350 | $5,456,949 | Sep 1 | Sony Pictures Releasing | false | 
| 41 | V for Vendetta | - | - | - | $5,435,193 | 302 | $5,435,193 | Apr 7 | Warner Bros. | false | 
| 42 | Open Season | - | - | - | $5,213,071 | 400 | $5,901,402 | Nov 10 | Sony Pictures Releasing | false | 
| 43 | Scary Movie 4 | - | - | - | $5,120,124 | 400 | $5,193,603 | Jun 23 | Buena Vista International | false | 
| 44 | Underworld: Evolution | - | - | - | $4,858,974 | 326 | $4,858,974 | Feb 3 | Filmax | false | 
| 45 | The Wild | - | - | - | $4,745,144 | 382 | $5,305,708 | Apr 12 | Buena Vista International | false | 
| 46 | The 2 Sides of the Bed | - | - | - | $4,740,244 | 382 | $9,391,218 | Dec 23 | Buena Vista International | false | 
| 47 | The Fast and the Furious: Tokyo Drift | - | - | - | $4,738,552 | 225 | $4,738,552 | Jul 21 | United International Pictures | false | 
| 48 | Lucky Number Slevin | - | - | - | $4,535,108 | 405 | $4,535,108 | Apr 7 | TriPictures | false | 
| 49 | Fun with Dick and Jane | - | - | - | $4,472,511 | 317 | $4,472,511 | Feb 10 | Sony Pictures Releasing | false | 
| 50 | King Kong | - | - | - | $4,470,785 | 513 | $15,149,112 | Dec 14 | United International Pictures | false | 
| 51 | Silent Hill | - | - | - | $4,403,940 | 180 | $4,403,940 | Jul 28 | United International Pictures | false | 
| 52 | The Family Stone | - | - | - | $4,378,866 | 251 | $4,510,592 | Jan 5 | 20th Century Fox International | false | 
| 53 | Bandidas | - | - | - | $4,370,015 | 250 | $4,370,015 | Aug 4 | 20th Century Fox International | false | 
| 54 | Good Night, and Good Luck. | - | - | - | $4,329,211 | 118 | $4,329,211 | Feb 10 | Manga Entertainment | false | 
| 55 | A Good Year | - | - | - | $4,307,577 | 300 | $4,307,577 | Nov 3 | 20th Century Fox International | false | 
| 56 | Date Movie | - | - | - | $4,252,866 | 275 | $4,252,866 | Mar 17 | 20th Century Fox International | false | 
| 57 | The Omen | - | - | - | $4,185,702 | 282 | $4,723,369 | Jun 9 | 20th Century Fox International | false | 
| 58 | Hoodwinked | - | - | - | $4,161,423 | 258 | $4,161,423 | Sep 22 | Manga Entertainment | false | 
| 59 | The Break-Up | - | - | - | $4,154,697 | 228 | $4,154,697 | Sep 15 | United International Pictures | false | 
| 60 | Æon Flux | - | - | - | $4,074,727 | 311 | $4,256,221 | Jan 6 | Filmax | false | 
| 61 | The Lake House | - | - | - | $3,922,500 | 227 | $3,922,500 | Jun 30 | Warner Bros. | false | 
| 62 | The Holiday | - | - | - | $3,906,948 | 295 | $6,154,701 | Dec 5 | United International Pictures | false | 
| 63 | Failure to Launch | - | - | - | $3,806,731 | 222 | $3,806,731 | Apr 21 | United International Pictures | false | 
| 64 | Pride & Prejudice | - | - | - | $3,726,496 | 194 | $3,726,496 | Feb 10 | United International Pictures | false | 
| 65 | Syriana | - | - | - | $3,702,318 | 206 | $3,702,318 | Mar 3 | Warner Bros. | false | 
| 66 | The Black Dahlia | - | - | - | $3,579,354 | 240 | $3,741,193 | Oct 20 | TriPictures | false | 
| 67 | Lord of War | - | - | - | $3,543,503 | 200 | $3,543,503 | Jun 30 | Sony Pictures Releasing | false | 
| 68 | Firewall | - | - | - | $3,471,324 | 302 | $3,471,324 | Mar 24 | Warner Bros. | false | 
| 69 | Nobody Is Perfect | - | - | - | $3,463,230 | 201 | $3,463,230 | Oct 27 | Sony Pictures Releasing | false | 
| 70 | Cheaper by the Dozen 2 | - | - | - | $3,373,499 | 305 | $6,588,656 | Dec 23 | 20th Century Fox International | false | 
| 71 | Eight Below | - | - | - | $3,360,543 | 225 | $3,360,543 | Apr 28 | Buena Vista International | false | 
| 72 | United 93 | - | - | - | $3,308,836 | 134 | $3,579,543 | Aug 23 | United International Pictures | false | 
| 73 | Sky High | - | - | - | $3,298,866 | 252 | $3,298,866 | Feb 24 | Buena Vista International | false | 
| 74 | Salvador | - | - | - | $3,235,528 | 190 | $3,235,528 | Sep 15 | Warner Bros. | false | 
| 75 | An American Haunting | - | - | - | $3,103,045 | 242 | $3,103,045 | Aug 18 | DeAPlaneta | false | 
| 76 | Take the Lead | - | - | - | $3,066,028 | 260 | $3,066,028 | Apr 28 | TriPictures | false | 
| 77 | My Name Is Juani | - | - | - | $2,971,263 | 186 | $2,971,263 | Oct 20 | Manga Entertainment | false | 
| 78 | Basic Instinct 2 | - | - | - | $2,923,255 | 348 | $2,923,255 | Mar 31 | United International Pictures | false | 
| 79 | Borat | - | - | - | $2,826,970 | 289 | $2,882,312 | Nov 17 | 20th Century Fox International | false | 
| 80 | Bambi II | - | - | - | $2,810,462 | 200 | $2,810,462 | Feb 3 | Buena Vista International | false | 
| 81 | Arthur and the Invisibles | - | - | - | $2,797,959 | 378 | $4,918,398 | Dec 15 | New World Pictures | false | 
| 82 | The Shaggy Dog | - | - | - | $2,795,617 | 350 | $2,795,617 | Jul 21 | Buena Vista International | false | 
| 83 | Rumor Has It... | - | - | - | $2,736,483 | 278 | $2,736,483 | Feb 17 | Warner Bros. | false | 
| 84 | Nanny McPhee | - | - | - | $2,730,090 | 229 | $2,730,090 | Apr 7 | United International Pictures | false | 
| 85 | Little Miss Sunshine | - | - | - | $2,660,350 | 179 | $4,688,542 | Oct 20 | 20th Century Fox International | false | 
| 86 | Just My Luck | - | - | - | $2,647,114 | 250 | $2,647,114 | Jun 16 | 20th Century Fox International | false | 
| 87 | The Hills Have Eyes | - | - | - | $2,642,854 | 285 | $2,642,854 | Jun 30 | 20th Century Fox International | false | 
| 88 | Casanova | - | - | - | $2,637,661 | 250 | $2,637,661 | Feb 17 | Buena Vista International | false | 
| 89 | The Guardian | - | - | - | $2,618,265 | 406 | $3,210,794 | Oct 11 | Buena Vista International | false | 
| 90 | The Tiger and the Snow | - | - | - | $2,590,529 | 160 | $2,590,529 | Jul 7 | 20th Century Fox International | false | 
| 91 | Los mánagers | - | - | - | $2,473,455 | 215 | $2,498,903 | Jul 7 | Filmax | false | 
| 92 | Prime | - | - | - | $2,453,321 | 241 | $2,453,321 | Feb 3 | Aurum Films | false | 
| 93 | Bee Season | - | - | - | $2,342,463 | 225 | $2,342,463 | Apr 28 | 20th Century Fox International | false | 
| 94 | Zathura: A Space Adventure | - | - | - | $2,340,597 | 225 | $2,340,597 | Mar 10 | Sony Pictures Releasing | false | 
| 95 | The New World 2005 Re-release | - | - | - | $2,317,758 | 185 | $2,317,758 | Feb 24 | TriPictures | false | 
| 96 | Barnyard | - | - | - | $2,302,952 | 238 | $2,302,952 | Oct 27 | United International Pictures | false | 
| 97 | The Jacket | - | - | - | $2,249,954 | 202 | $2,334,033 | Jan 6 | TriPictures | false | 
| 98 | Tristan + Isolde | - | - | - | $2,230,527 | 260 | $2,230,527 | Mar 10 | 20th Century Fox International | false | 
| 99 | Final Destination 3 | - | - | - | $2,225,496 | 255 | $2,225,496 | Mar 17 | TriPictures | false | 
| 100 | Hostel | - | - | - | $2,220,513 | 250 | $2,220,513 | Mar 24 | Sony Pictures Releasing | false | 
| 101 | Isi/Disi: Alto voltaje | - | - | - | $2,194,607 | 301 | $2,194,607 | Dec 1 | Azteca Films | false | 
| 102 | The Ant Bully | - | - | - | $2,181,265 | 265 | $2,181,265 | Sep 8 | Warner Bros. | false | 
| 103 | Goya's Ghosts | - | - | - | $2,119,985 | 363 | $2,198,929 | Nov 10 | Warner Bros. | false | 
| 104 | Summer Rain | - | - | - | $2,116,769 | 289 | $2,119,424 | Dec 1 | 20th Century Fox International | false | 
| 105 | GAL | - | - | - | $2,079,303 | 350 | $2,079,303 | Nov 3 | 20th Century Fox International | false | 
| 106 | Capote | - | - | - | $2,058,336 | 107 | $2,058,336 | Feb 24 | Sony Pictures Releasing | false | 
| 107 | Harry Potter and the Goblet of Fire | - | - | - | $2,045,927 | 527 | $24,156,390 | Nov 24 | Warner Bros. | false | 
| 108 | Jarhead | - | - | - | $2,042,640 | 217 | $2,122,937 | Jan 5 | United International Pictures | false | 
| 109 | 16 Blocks | - | - | - | $2,027,957 | 240 | $2,362,372 | Apr 12 | Filmax | false | 
| 110 | My Super Ex-Girlfriend | - | - | - | $2,027,732 | 299 | $2,027,732 | Sep 22 | 20th Century Fox International | false | 
| 111 | Children of Men | - | - | - | $1,998,110 | 165 | $2,180,299 | Oct 20 | United International Pictures | false | 
| 112 | The Education of Fairies | - | - | - | $1,991,758 | 229 | $1,991,758 | Jun 23 | Alta Films | false | 
| 113 | The Queen | - | - | - | $1,943,732 | 185 | $2,887,973 | Nov 10 | Vértigo Films | false | 
| 114 | The Maidens' Conspiracy | - | - | - | $1,917,353 | 261 | $1,917,353 | Apr 7 | DeAPlaneta | false | 
| 115 | Chaos | - | - | - | $1,795,554 | 169 | $1,795,554 | May 12 | TriPictures | false | 
| 116 | The Covenant | - | - | - | $1,744,091 | 250 | $3,041,464 | Dec 22 | Sony Pictures Releasing | false | 
| 117 | Manual of Love | - | - | - | $1,724,574 | 78 | $1,907,699 | Dec 30 | Notro Films | false | 
| 118 | Match Point | - | - | - | $1,724,153 | 151 | $9,142,118 | Nov 4 | On Pictures | false | 
| 119 | Alone in the Dark | - | - | - | $1,716,320 | 218 | $1,716,320 | Jan 20 | New World Pictures | false | 
| 120 | The Fog | - | - | - | $1,655,587 | 210 | $1,655,587 | Jan 27 | Sony Pictures Releasing | false | 
| 121 | Crossing Borders | - | - | - | $1,630,615 | 198 | $1,630,859 | May 5 | Alta Films | false | 
| 122 | Yours, Mine & Ours | - | - | - | $1,628,768 | 100 | $1,778,306 | Apr 12 | Sony Pictures Releasing | false | 
| 123 | Edison | - | - | - | $1,623,929 | 144 | $1,623,929 | Sep 1 | Filmax | false | 
| 124 | Proof | - | - | - | $1,597,931 | 123 | $1,597,931 | Mar 17 | Buena Vista International | false | 
| 125 | The Wind that Shakes the Barley | - | - | - | $1,570,172 | 109 | $1,570,172 | Sep 15 | Alta Films | false | 
| 126 | Welcome Home | - | - | - | $1,565,855 | 150 | $1,565,855 | Apr 7 | 20th Century Fox International | false | 
| 127 | RV | - | - | - | $1,545,613 | 200 | $1,545,613 | Jun 30 | Sony Pictures Releasing | false | 
| 128 | Derailed | - | - | - | $1,488,122 | 200 | $1,488,122 | Jan 16 | Buena Vista International | false | 
| 129 | The Constant Gardener | - | - | - | $1,436,197 | 195 | $7,418,017 | Nov 4 | United International Pictures | false | 
| 130 | When a Stranger Calls | - | - | - | $1,402,767 | 250 | $1,402,767 | Jun 2 | Sony Pictures Releasing | false | 
| 131 | Babel | - | - | - | $1,297,997 | 214 | $13,981,232 | Dec 29 | United International Pictures | false | 
| 132 | You, Me and Dupree | - | - | - | $1,283,785 | 218 | $1,637,599 | Oct 11 | United International Pictures | false | 
| 133 | Crank | - | - | - | $1,272,001 | 259 | $1,607,281 | Oct 11 | Aurum Films | false | 
| 134 | Half Light | - | - | - | $1,260,584 | 165 | $1,260,584 | Jun 9 | Filmax | false | 
| 135 | Ultraviolet | - | - | - | $1,241,998 | 190 | $1,241,998 | Jun 16 | Sony Pictures Releasing | false | 
| 136 | The Texas Chainsaw Massacre: The Beginning | - | - | - | $1,237,205 | 161 | $1,291,909 | Nov 3 | TriPictures | false | 
| 137 | Cándida | - | - | - | $1,225,212 | 249 | $2,175,947 | Dec 22 | 20th Century Fox International | false | 
| 138 | Just Friends | - | - | - | $1,224,533 | 240 | $1,224,533 | Feb 17 | Aurum Films | false | 
| 139 | My Quick Way Out | - | - | - | $1,220,200 | 140 | $1,220,523 | Jan 13 | Warner Sogefilms A.I.E. | false | 
| 140 | Domino | - | - | - | $1,192,373 | 264 | $1,192,373 | Jul 21 | Aurum Films | false | 
| 141 | Walk the Line | - | - | - | $1,185,249 | 206 | $1,185,249 | Feb 3 | 20th Century Fox International | false | 
| 142 | The Night of the Sunflowers | - | - | - | $1,123,189 | 90 | $1,123,189 | Aug 25 | Alta Films | false | 
| 143 | Snakes on a Plane | - | - | - | $1,108,743 | 274 | $1,108,743 | Oct 6 | TriPictures | false | 
| 144 | Doom | - | - | - | $1,083,387 | 190 | $1,749,594 | Dec 30 | United International Pictures | false | 
| 145 | The Wicker Man | - | - | - | $1,068,550 | 251 | $1,068,550 | Oct 20 | Filmax | false | 
| 146 | Curious George | - | - | - | $1,054,847 | 189 | $1,054,847 | Aug 4 | United International Pictures | false | 
| 147 | The Protector | - | - | - | $1,041,077 | 178 | $1,041,077 | Mar 10 | Manga Entertainment | false | 
| 148 | Open Water 2: Adrift | - | - | - | $1,034,542 | 153 | $1,034,542 | Aug 18 | On Pictures | false | 
| 149 | The Cave | - | - | - | $1,031,864 | 100 | $1,067,257 | Jan 6 | Sony Pictures Releasing | false | 
| 150 | On Probation | - | - | - | $1,026,514 | 94 | $1,026,514 | May 26 | - | false | 
| 151 | The Lazarus Child | - | - | - | $1,020,226 | 145 | $1,020,226 | Sep 22 | Aurum Films | false | 
| 152 | Doogal | - | - | - | $982,405 | 213 | $1,171,969 | Dec 30 | Aurum Films | false | 
| 153 | Unknown | - | - | - | $980,678 | 212 | $1,657,995 | Dec 22 | DeAPlaneta | false | 
| 154 | Keeping Mum | - | - | - | $971,806 | 215 | $971,806 | Jan 27 | TriPictures | false | 
| 155 | Water Canadian Release | - | - | - | $959,510 | 21 | $1,339,332 | Mar 3 | Golem Distribución | false | 
| 156 | She's the Man | - | - | - | $951,247 | 152 | $951,247 | Jul 12 | Filmax | false | 
| 157 | Dark Blue Almost Black | - | - | - | $931,354 | 67 | $931,354 | Mar 31 | Alta Films | false | 
| 158 | The Nativity Story | - | - | - | $923,887 | 220 | $1,103,856 | Dec 1 | TriPictures | false | 
| 159 | Chicken Little | - | - | - | $892,442 | 394 | $11,077,762 | Nov 18 | Buena Vista International | false | 
| 160 | Man-Thing | - | - | - | $887,002 | 156 | $887,002 | Mar 3 | Flins & Piniculas | false | 
| 161 | Hard Candy | - | - | - | $860,120 | 84 | $860,120 | May 12 | Aurum Films | false | 
| 162 | Luther | - | - | - | $850,415 | 86 | $1,798,095 | Dec 16 | Karma Films | false | 
| 163 | The Santa Clause 3: The Escape Clause | - | - | - | $846,591 | 194 | $1,239,447 | Dec 22 | Buena Vista International | false | 
| 164 | Caché | - | - | - | $830,950 | 38 | $830,950 | Jan 20 | Golem Distribución | false | 
| 165 | Copying Beethoven | - | - | - | $830,351 | 91 | $1,356,221 | Oct 20 | Notro Films | false | 
| 166 | The Three Burials of Melquiades Estrada | - | - | - | $810,975 | 105 | $812,026 | Feb 17 | Alta Films | false | 
| 167 | The Assassination of Richard Nixon | - | - | - | $810,056 | 111 | $810,056 | Jun 9 | Manga Entertainment | false | 
| 168 | The Valet | - | - | - | $785,765 | 96 | $785,765 | Jun 9 | On Pictures | false | 
| 169 | The Near East | - | - | - | $775,228 | 106 | $775,228 | Aug 18 | 20th Century Fox International | false | 
| 170 | Asterix and the Vikings | - | - | - | $772,456 | 201 | $772,456 | Jun 30 | DeAPlaneta | false | 
| 171 | Howl's Moving Castle | - | - | - | $730,865 | 104 | $730,865 | Mar 3 | Aurum Films | false | 
| 172 | Man About Town | - | - | - | $727,246 | 226 | $727,246 | Jun 9 | DeAPlaneta | false | 
| 173 | Nine Lives | - | - | - | $698,093 | 23 | $698,093 | Sep 22 | Versus Entertainment | false | 
| 174 | Empire of the Wolves | - | - | - | $692,343 | 158 | $1,011,040 | Dec 30 | On Pictures | false | 
| 175 | Unaccompanied Minors | - | - | - | $658,628 | 198 | $882,134 | Dec 15 | Warner Bros. | false | 
| 176 | La máquina de bailar | - | - | - | $653,124 | 249 | $653,124 | Sep 22 | United International Pictures | false | 
| 177 | The Breed | - | - | - | $625,095 | 178 | $625,095 | Aug 4 | New World Pictures | false | 
| 178 | C.R.A.Z.Y. | - | - | - | $622,932 | 30 | $622,932 | Aug 4 | Golem Distribución | false | 
| 179 | Talladega Nights: The Ballad of Ricky Bobby | - | - | - | $612,801 | 250 | $612,801 | Aug 18 | Sony Pictures Releasing | false | 
| 180 | Cabeza de perro | - | - | - | $611,525 | 200 | $611,525 | Oct 6 | Alta Films | false | 
| 181 | The Weather Man | - | - | - | $588,069 | 53 | $588,069 | Jan 13 | United International Pictures | false | 
| 182 | The Secret Life of Words | - | - | - | $585,105 | 107 | $4,092,793 | Oct 21 | Warner Bros. | false | 
| 183 | Nacho Libre | - | - | - | $560,650 | 152 | $560,650 | Aug 18 | United International Pictures | false | 
| 184 | Waiting... | - | - | - | $527,905 | 175 | $527,905 | Aug 4 | Aurum Films | false | 
| 185 | One Missed Call 2 | - | - | - | $521,941 | 71 | $521,941 | Apr 7 | United International Pictures | false | 
| 186 | Two for the Money | - | - | - | $514,178 | 100 | $514,178 | Feb 24 | United International Pictures | false | 
| 187 | Mrs. Henderson Presents | - | - | - | $509,933 | 99 | $509,933 | Mar 3 | Vértigo Films | false | 
| 188 | Shutter | - | - | - | $493,341 | 129 | $493,341 | Jun 23 | Manga Entertainment | false | 
| 189 | DOA: Dead or Alive | - | - | - | $492,579 | 244 | $492,579 | Nov 17 | Filmax | false | 
| 190 | What the #$*! Do We (K)now!? 2005 Re-release | - | - | - | $471,242 | 15 | $646,626 | May 5 | Karma Films | false | 
| 191 | Vete de mí | - | - | - | $459,324 | 72 | $459,324 | Sep 29 | United International Pictures | false | 
| 192 | You Are So Beautiful | - | - | - | $448,048 | 76 | $448,048 | Apr 21 | On Pictures | false | 
| 193 | Fearless | - | - | - | $442,179 | 150 | $442,179 | Jun 2 | United International Pictures | false | 
| 194 | Jackass Number Two | - | - | - | $440,436 | 100 | $440,436 | Nov 3 | United International Pictures | false | 
| 195 | Summer in Berlin | - | - | - | $434,761 | 40 | $434,761 | Aug 4 | Alta Films | false | 
| 196 | The Matador | - | - | - | $432,182 | 133 | $488,518 | Apr 12 | Manga Entertainment | false | 
| 197 | La semana que viene (sin falta) | - | - | - | $409,773 | 164 | $409,773 | Mar 3 | DeAPlaneta | false | 
| 198 | Breakfast on Pluto | - | - | - | $408,071 | 49 | $408,071 | Aug 25 | Vértigo Films | false | 
| 199 | Clerks II | - | - | - | $397,603 | 124 | $397,603 | Sep 8 | DeAPlaneta | false | 
| 200 | North Country | - | - | - | $396,154 | 34 | $396,154 | Mar 31 | Warner Bros. | false |