| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Pirates of the Caribbean: Dead Man's Chest | - | - | - | $423,317,154 | 4,133 | $423,315,812 | Jul 7 | Walt Disney Studios Motion Pictures | false |
| 2 | Cars | - | - | - | $244,082,982 | 3,988 | $244,082,982 | Jun 9 | Walt Disney Studios Motion Pictures | false |
| 3 | X-Men: The Last Stand | - | - | - | $234,362,462 | 3,714 | $234,362,462 | May 26 | Twentieth Century Fox | false |
| 4 | The Da Vinci Code | - | - | - | $217,536,138 | 3,757 | $217,536,138 | May 19 | Sony Pictures Entertainment (SPE) | false |
| 5 | Superman Returns | - | - | - | $200,081,192 | 4,065 | $200,081,192 | Jun 28 | Warner Bros. | false |
| 6 | Ice Age: The Meltdown | - | - | - | $195,330,621 | 3,969 | $195,330,621 | Mar 31 | Twentieth Century Fox | false |
| 7 | Happy Feet | - | - | - | $175,967,627 | 3,804 | $198,000,317 | Nov 17 | Warner Bros. | false |
| 8 | Over the Hedge | - | - | - | $155,019,340 | 4,093 | $155,019,340 | May 19 | DreamWorks | false |
| 9 | Casino Royale | - | - | - | $153,531,944 | 3,443 | $167,445,960 | Nov 17 | Sony Pictures Entertainment (SPE) | false |
| 10 | Talladega Nights: The Ballad of Ricky Bobby | - | - | - | $148,213,377 | 3,807 | $148,213,377 | Aug 4 | Sony Pictures Entertainment (SPE) | false |
| 11 | Click | - | - | - | $137,355,633 | 3,764 | $137,355,633 | Jun 23 | Revolution Studios | false |
| 12 | Mission: Impossible III | - | - | - | $134,029,801 | 4,059 | $134,029,801 | May 5 | Paramount Pictures | false |
| 13 | Borat: Cultural Learnings of America for Make Benefit Glorious Nation of Kazakhstan | - | - | - | $125,601,414 | 2,611 | $128,505,958 | Nov 3 | Twentieth Century Fox | false |
| 14 | The Devil Wears Prada | - | - | - | $124,740,460 | 2,882 | $124,740,460 | Jun 30 | Twentieth Century Fox | false |
| 15 | The Departed | - | - | - | $120,359,613 | 3,017 | $132,384,315 | Oct 6 | Warner Bros. | false |
| 16 | The Break-Up | - | - | - | $118,703,275 | 3,146 | $118,703,275 | Jun 2 | Universal Pictures | false |
| 17 | Night at the Museum | - | - | - | $115,822,154 | 3,768 | $250,863,268 | Dec 22 | Twentieth Century Fox | false |
| 18 | The Pursuit of Happyness | - | - | - | $98,411,670 | 3,169 | $163,566,459 | Dec 15 | Sony Pictures Entertainment (SPE) | false |
| 19 | Scary Movie 4 | - | - | - | $90,710,620 | 3,674 | $90,710,620 | Apr 14 | - | false |
| 20 | Failure to Launch | - | - | - | $88,715,192 | 3,202 | $88,715,192 | Mar 10 | Paramount Pictures | false |
| 21 | Inside Man | - | - | - | $88,513,495 | 2,867 | $88,513,495 | Mar 24 | Universal Pictures | false |
| 22 | Open Season | - | - | - | $84,303,558 | 3,833 | $85,105,259 | Sep 29 | Sony Pictures Entertainment (SPE) | false |
| 23 | The Santa Clause 3: The Escape Clause | - | - | - | $83,549,047 | 3,458 | $84,500,122 | Nov 3 | Walt Disney Studios Motion Pictures | false |
| 24 | The Chronicles of Narnia: The Lion, the Witch and the Wardrobe | - | - | - | $82,270,870 | 3,853 | $291,710,957 | Dec 9 | Walt Disney Studios Motion Pictures | false |
| 25 | The Pink Panther | - | - | - | $82,226,474 | 3,477 | $82,226,474 | Feb 10 | Sony Pictures Entertainment (SPE) | false |
| 26 | Eight Below | - | - | - | $81,612,565 | 3,122 | $81,612,565 | Feb 17 | Walt Disney Studios Motion Pictures | false |
| 27 | Saw III | - | - | - | $80,238,724 | 3,167 | $80,238,724 | Oct 27 | Lionsgate | false |
| 28 | Nacho Libre | - | - | - | $80,197,993 | 3,083 | $80,197,993 | Jun 16 | Paramount Pictures | false |
| 29 | You, Me and Dupree | - | - | - | $75,628,110 | 3,137 | $75,628,110 | Jul 14 | Universal Pictures | false |
| 30 | Monster House | - | - | - | $73,661,010 | 3,553 | $73,661,010 | Jul 21 | Sony Pictures Entertainment (SPE) | false |
| 31 | Jackass Number Two | - | - | - | $72,778,712 | 3,063 | $72,778,712 | Sep 22 | Paramount Pictures | false |
| 32 | Barnyard | - | - | - | $72,637,803 | 3,311 | $72,637,803 | Aug 4 | Paramount Pictures | false |
| 33 | RV | - | - | - | $71,726,025 | 3,651 | $71,726,025 | Apr 28 | Sony Pictures Entertainment (SPE) | false |
| 34 | Brokeback Mountain | - | - | - | $70,612,954 | 2,089 | $83,043,761 | Dec 9 | Focus Features | false |
| 35 | V for Vendetta | - | - | - | $70,511,035 | 3,365 | $70,511,035 | Mar 17 | Warner Bros. | false |
| 36 | World Trade Center | - | - | - | $70,278,893 | 3,021 | $70,278,893 | Aug 9 | Paramount Pictures | false |
| 37 | Big Momma's House 2 | - | - | - | $70,165,972 | 3,261 | $70,165,972 | Jan 27 | Twentieth Century Fox | false |
| 38 | Step Up | - | - | - | $65,326,375 | 2,647 | $65,328,121 | Aug 11 | Walt Disney Studios Motion Pictures | false |
| 39 | Miami Vice | - | - | - | $63,450,470 | 3,026 | $63,450,470 | Jul 28 | Universal Pictures | false |
| 40 | Madea's Family Reunion | - | - | - | $63,257,940 | 2,194 | $63,257,940 | Feb 24 | Lionsgate | false |
| 41 | The Fast and the Furious: Tokyo Drift | - | - | - | $62,514,415 | 3,030 | $62,514,415 | Jun 16 | Universal Pictures | false |
| 42 | Underworld: Evolution | - | - | - | $62,318,875 | 3,207 | $62,318,875 | Jan 20 | Screen Gems | false |
| 43 | Flushed Away | - | - | - | $61,733,119 | 3,707 | $64,665,672 | Nov 3 | DreamWorks | false |
| 44 | Deja Vu | - | - | - | $61,574,479 | 3,108 | $64,038,616 | Nov 22 | Walt Disney Studios Motion Pictures | false |
| 45 | The Shaggy Dog | - | - | - | $61,123,569 | 3,501 | $61,123,569 | Mar 10 | Walt Disney Studios Motion Pictures | false |
| 46 | Poseidon | - | - | - | $60,674,817 | 3,555 | $60,674,817 | May 12 | Warner Bros. | false |
| 47 | The Benchwarmers | - | - | - | $59,843,754 | 3,282 | $59,843,754 | Apr 7 | Revolution Studios | false |
| 48 | Little Miss Sunshine | - | - | - | $59,489,083 | 1,602 | $59,891,098 | Jul 26 | Fox Searchlight Pictures | false |
| 49 | King Kong | - | - | - | $59,370,190 | 3,627 | $218,080,025 | Dec 14 | Universal Pictures | false |
| 50 | Little Man | - | - | - | $58,645,052 | 2,537 | $58,645,052 | Jul 14 | Revolution Studios | false |
| 51 | Curious George | - | - | - | $58,360,760 | 2,609 | $58,360,760 | Feb 10 | Universal Pictures | false |
| 52 | Invincible | - | - | - | $57,806,056 | 2,987 | $57,806,952 | Aug 25 | Walt Disney Studios Motion Pictures | false |
| 53 | Eragon | - | - | - | $56,420,434 | 3,030 | $75,030,163 | Dec 15 | Twentieth Century Fox | false |
| 54 | Fun with Dick and Jane | - | - | - | $56,270,199 | 3,239 | $110,332,737 | Dec 21 | Sony Pictures Entertainment (SPE) | false |
| 55 | The Guardian | - | - | - | $54,957,777 | 3,241 | $55,011,732 | Sep 29 | Walt Disney Studios Motion Pictures | false |
| 56 | The Omen | - | - | - | $54,607,383 | 2,723 | $54,607,383 | Jun 6 | Twentieth Century Fox | false |
| 57 | Final Destination 3 | - | - | - | $54,097,021 | 2,880 | $54,098,051 | Feb 10 | New Line Cinema | false |
| 58 | Charlotte's Web | - | - | - | $52,532,601 | 3,745 | $82,985,708 | Dec 15 | Paramount Pictures | false |
| 59 | The Prestige | - | - | - | $52,455,154 | 2,305 | $53,089,891 | Oct 20 | Walt Disney Studios Motion Pictures | false |
| 60 | The Lake House | - | - | - | $52,330,111 | 2,645 | $52,330,111 | Jun 16 | Warner Bros. | false |
| 61 | Hoodwinked | - | - | - | $51,386,611 | 3,020 | $51,386,611 | Dec 16 | The Weinstein Company | false |
| 62 | The Holiday | - | - | - | $50,029,085 | 2,698 | $63,224,849 | Dec 8 | Sony Pictures Entertainment (SPE) | false |
| 63 | Firewall | - | - | - | $48,751,189 | 2,840 | $48,751,189 | Feb 10 | Warner Bros. | false |
| 64 | Date Movie | - | - | - | $48,548,426 | 2,898 | $48,548,426 | Feb 17 | Twentieth Century Fox | false |
| 65 | Rocky Balboa | - | - | - | $47,940,632 | 3,019 | $70,270,943 | Dec 20 | Metro-Goldwyn-Mayer (MGM) | false |
| 66 | When a Stranger Calls | - | - | - | $47,860,214 | 3,004 | $47,860,214 | Feb 3 | Screen Gems | false |
| 67 | Hostel | - | - | - | $47,326,473 | 2,337 | $47,326,473 | Jan 6 | Lionsgate | false |
| 68 | Nanny McPhee | - | - | - | $47,144,110 | 2,148 | $47,144,110 | Jan 27 | Universal Pictures | false |
| 69 | Silent Hill | - | - | - | $46,982,632 | 2,932 | $46,982,632 | Apr 21 | Sony Pictures Entertainment (SPE) | false |
| 70 | Apocalypto | - | - | - | $42,654,236 | 2,465 | $50,866,635 | Dec 8 | Walt Disney Studios Motion Pictures | false |
| 71 | Glory Road | - | - | - | $42,647,449 | 2,397 | $42,647,449 | Jan 13 | Walt Disney Studios Motion Pictures | false |
| 72 | Lady in the Water | - | - | - | $42,285,169 | 3,235 | $42,285,169 | Jul 21 | Warner Bros. | false |
| 73 | The Hills Have Eyes | - | - | - | $41,778,863 | 2,621 | $41,778,863 | Mar 10 | Fox Searchlight Pictures | false |
| 74 | John Tucker Must Die | - | - | - | $41,011,711 | 2,566 | $41,011,711 | Jul 28 | Twentieth Century Fox | false |
| 75 | Stranger Than Fiction | - | - | - | $40,435,190 | 2,270 | $40,660,952 | Nov 10 | Sony Pictures Entertainment (SPE) | false |
| 76 | The Illusionist | - | - | - | $39,770,667 | 1,438 | $39,868,642 | Aug 18 | Yari Film Group Releasing | false |
| 77 | The Texas Chainsaw Massacre: The Beginning | - | - | - | $39,505,863 | 2,820 | $39,517,763 | Oct 6 | New Line Cinema | false |
| 78 | The Grudge 2 | - | - | - | $39,143,839 | 3,214 | $39,143,839 | Oct 13 | Sony Pictures Entertainment (SPE) | false |
| 79 | Gridiron Gang | - | - | - | $38,432,823 | 3,510 | $38,432,823 | Sep 15 | Sony Pictures Entertainment (SPE) | false |
| 80 | Last Holiday | - | - | - | $38,399,961 | 2,514 | $38,399,961 | Jan 13 | Paramount Pictures | false |
| 81 | The Wild | - | - | - | $37,384,046 | 2,854 | $37,384,046 | Apr 14 | Walt Disney Studios Motion Pictures | false |
| 82 | Man of the Year | - | - | - | $37,327,390 | 2,626 | $37,327,390 | Oct 13 | Universal Pictures | false |
| 83 | Dreamgirls | - | - | - | $37,064,395 | 2,797 | $103,365,956 | Dec 15 | DreamWorks | false |
| 84 | 16 Blocks | - | - | - | $36,895,141 | 2,706 | $36,895,141 | Mar 3 | Warner Bros. | false |
| 85 | Cheaper by the Dozen 2 | - | - | - | $36,612,259 | 3,211 | $82,571,173 | Dec 21 | Twentieth Century Fox | false |
| 86 | The Nativity Story | - | - | - | $36,418,000 | 3,083 | $37,629,831 | Dec 1 | New Line Cinema | false |
| 87 | Accepted | - | - | - | $36,323,505 | 2,917 | $36,323,505 | Aug 18 | Universal Pictures | false |
| 88 | The Sentinel | - | - | - | $36,280,697 | 2,851 | $36,280,697 | Apr 21 | Twentieth Century Fox | false |
| 89 | Blood Diamond | - | - | - | $35,726,534 | 1,920 | $57,377,916 | Dec 8 | Warner Bros. | false |
| 90 | Munich | - | - | - | $35,128,025 | 1,498 | $47,403,685 | Dec 23 | Universal Pictures | false |
| 91 | The Good Shepherd | - | - | - | $35,066,495 | 2,250 | $59,952,835 | Dec 22 | Universal Pictures | false |
| 92 | Deck the Halls | - | - | - | $34,753,961 | 3,205 | $35,093,569 | Nov 22 | Twentieth Century Fox | false |
| 93 | Take the Lead | - | - | - | $34,741,730 | 3,009 | $34,742,066 | Apr 7 | New Line Cinema | false |
| 94 | Snakes on a Plane | - | - | - | $34,020,741 | 3,555 | $34,020,814 | Aug 18 | New Line Cinema | false |
| 95 | She's the Man | - | - | - | $33,741,133 | 2,631 | $33,741,133 | Mar 17 | DreamWorks | false |
| 96 | Flags of Our Fathers | - | - | - | $33,602,376 | 2,375 | $33,602,376 | Oct 20 | DreamWorks | false |
| 97 | Memoirs of a Geisha | - | - | - | $32,166,624 | 1,654 | $57,490,508 | Dec 9 | Sony Pictures Entertainment (SPE) | false |
| 98 | United 93 | - | - | - | $31,483,450 | 1,871 | $31,483,450 | Apr 28 | Universal Pictures | false |
| 99 | Walk the Line | - | - | - | $28,668,398 | 3,160 | $119,519,402 | Nov 18 | Twentieth Century Fox | false |
| 100 | Employee of the Month | - | - | - | $28,444,855 | 2,579 | $28,444,855 | Oct 6 | Lionsgate | false |
| 101 | Garfield: A Tail of Two Kitties | - | - | - | $28,426,747 | 2,981 | $28,426,747 | Jun 16 | Twentieth Century Fox | false |
| 102 | The Queen | - | - | - | $28,191,739 | 1,850 | $56,441,711 | Sep 30 | Miramax | false |
| 103 | The Ant Bully | - | - | - | $28,142,535 | 3,050 | $28,142,535 | Jul 28 | Warner Bros. | false |
| 104 | Crank | - | - | - | $27,838,408 | 2,515 | $27,838,408 | Sep 1 | Lionsgate | false |
| 105 | Stick It | - | - | - | $26,910,056 | 2,044 | $26,910,736 | Apr 28 | Walt Disney Studios Motion Pictures | false |
| 106 | The Descent | - | - | - | $26,024,456 | 2,095 | $26,024,456 | Aug 4 | Lionsgate | false |
| 107 | We Are Marshall | - | - | - | $25,128,312 | 2,606 | $43,545,364 | Dec 22 | Warner Bros. | false |
| 108 | Thank You for Smoking | - | - | - | $24,793,509 | 1,020 | $24,793,509 | Mar 17 | Fox Searchlight Pictures | false |
| 109 | Fearless | - | - | - | $24,637,306 | 1,810 | $24,633,730 | Sep 22 | Rogue Pictures | false |
| 110 | Clerks II | - | - | - | $24,148,068 | 2,150 | $24,148,068 | Jul 21 | - | false |
| 111 | An Inconvenient Truth | - | - | - | $23,814,997 | 587 | $24,146,161 | May 24 | Paramount Classics | false |
| 112 | The Wicker Man | - | - | - | $23,649,127 | 2,784 | $23,649,127 | Sep 1 | Warner Bros. | false |
| 113 | The Covenant | - | - | - | $23,380,495 | 2,681 | $23,380,495 | Sep 8 | Screen Gems | false |
| 114 | Stay Alive | - | - | - | $23,086,480 | 2,009 | $23,086,480 | Mar 24 | Walt Disney Studios Motion Pictures | false |
| 115 | Match Point | - | - | - | $22,702,604 | 512 | $23,151,529 | Dec 28 | DreamWorks Distribution | false |
| 116 | The Black Dahlia | - | - | - | $22,545,080 | 2,236 | $22,545,080 | Sep 15 | Universal Pictures | false |
| 117 | My Super Ex-Girlfriend | - | - | - | $22,530,295 | 2,702 | $22,530,295 | Jul 21 | Twentieth Century Fox | false |
| 118 | Lucky Number Slevin | - | - | - | $22,495,466 | 1,989 | $22,495,466 | Apr 7 | - | false |
| 119 | Deep Sea | - | - | - | $21,973,886 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 120 | Rumor Has It... | - | - | - | $21,730,356 | 2,815 | $43,000,262 | Dec 25 | Warner Bros. | false |
| 121 | Waist Deep | - | - | - | $21,331,895 | 1,006 | $21,344,312 | Jun 23 | Rogue Pictures | false |
| 122 | ATL | - | - | - | $21,170,563 | 1,602 | $21,170,563 | Mar 31 | Warner Bros. | false |
| 123 | Flicka | - | - | - | $20,888,606 | 2,877 | $21,000,147 | Oct 20 | Twentieth Century Fox | false |
| 124 | A Prairie Home Companion | - | - | - | $20,342,852 | 767 | $20,342,852 | Jun 9 | Picturehouse | false |
| 125 | Pulse | - | - | - | $20,264,436 | 2,323 | $20,264,436 | Aug 11 | - | false |
| 126 | Babel | - | - | - | $19,825,138 | 1,251 | $34,302,837 | Oct 27 | Paramount Vantage | false |
| 127 | Beerfest | - | - | - | $19,185,184 | 2,964 | $19,185,184 | Aug 25 | Warner Bros. | false |
| 128 | Akeelah and the Bee | - | - | - | $18,848,430 | 2,195 | $18,848,430 | Apr 28 | Lionsgate | false |
| 129 | The Marine | - | - | - | $18,782,953 | 2,545 | $18,844,784 | Oct 13 | Twentieth Century Fox | false |
| 130 | The Family Stone | - | - | - | $18,657,532 | 2,469 | $60,062,868 | Dec 16 | Twentieth Century Fox | false |
| 131 | Aquamarine | - | - | - | $18,597,342 | 2,538 | $18,597,342 | Mar 3 | Twentieth Century Fox | false |
| 132 | Ultraviolet | - | - | - | $18,535,812 | 2,558 | $18,535,812 | Mar 3 | Screen Gems | false |
| 133 | The Ringer | - | - | - | $18,163,047 | 1,853 | $35,428,675 | Dec 23 | Fox Searchlight Pictures | false |
| 134 | School for Scoundrels | - | - | - | $17,807,569 | 3,007 | $17,807,569 | Sep 29 | - | false |
| 135 | Just My Luck | - | - | - | $17,326,650 | 2,543 | $17,326,650 | May 12 | Twentieth Century Fox | false |
| 136 | Annapolis | - | - | - | $17,127,992 | 1,607 | $17,127,992 | Jan 27 | Walt Disney Studios Motion Pictures | false |
| 137 | Capote | - | - | - | $17,018,375 | 1,239 | $28,750,530 | Sep 30 | Sony Pictures Classics | false |
| 138 | Harry Potter and the Goblet of Fire | - | - | - | $16,731,856 | 3,858 | $290,013,036 | Nov 18 | Warner Bros. | false |
| 139 | An American Haunting | - | - | - | $16,290,949 | 1,703 | $16,298,046 | May 5 | Freestyle Releasing | false |
| 140 | Marie Antoinette | - | - | - | $15,962,471 | 870 | $15,962,471 | Oct 20 | Sony Pictures Entertainment (SPE) | false |
| 141 | Larry the Cable Guy: Health Inspector | - | - | - | $15,680,099 | 1,747 | $15,680,099 | Mar 24 | Lionsgate | false |
| 142 | See No Evil | - | - | - | $15,032,800 | 1,270 | $15,032,800 | May 19 | Lionsgate | false |
| 143 | Unaccompanied Minors | - | - | - | $14,993,733 | 2,775 | $16,655,224 | Dec 8 | Warner Bros. | false |
| 144 | Tristan + Isolde | - | - | - | $14,734,633 | 1,845 | $14,734,633 | Jan 13 | Twentieth Century Fox | false |
| 145 | Syriana | - | - | - | $14,676,762 | 1,775 | $50,824,620 | Nov 23 | Warner Bros. | false |
| 146 | Everyone's Hero | - | - | - | $14,523,101 | 2,898 | $14,523,101 | Sep 15 | Twentieth Century Fox | false |
| 147 | Hollywoodland | - | - | - | $14,425,753 | 1,551 | $14,426,251 | Sep 8 | Focus Features | false |
| 148 | One Night with the King | - | - | - | $13,394,029 | 909 | $13,395,961 | Oct 13 | 8x Entertainment | false |
| 149 | Friends with Money | - | - | - | $13,366,989 | 1,010 | $13,368,437 | Apr 7 | Sony Pictures Classics | false |
| 150 | Flyboys | - | - | - | $13,090,630 | 2,033 | $13,090,630 | Sep 22 | Metro-Goldwyn-Mayer (MGM) | false |
| 151 | How to Eat Fried Worms | - | - | - | $13,040,390 | 1,870 | $13,040,527 | Aug 25 | New Line Cinema | false |
| 152 | Bon Cop Bad Cop | - | - | - | $12,665,721 | 260 | $12,665,721 | Aug 4 | Alliance Atlantis Vivafilm | false |
| 153 | The New World 2005 Re-release | - | - | - | $12,588,149 | 811 | $12,712,093 | Dec 25 | New Line Cinema | false |
| 154 | Idlewild | - | - | - | $12,571,185 | 975 | $12,571,185 | Aug 25 | Universal Pictures | false |
| 155 | The Matador | - | - | - | $12,555,022 | 905 | $12,594,698 | Dec 30 | The Weinstein Company | false |
| 156 | Freedomland | - | - | - | $12,512,886 | 2,361 | $12,512,886 | Feb 17 | Revolution Studios | false |
| 157 | The Protector | - | - | - | $12,044,087 | 1,541 | $12,044,087 | Sep 8 | Dragon Dynasty | false |
| 158 | Zoom | - | - | - | $11,989,328 | 2,501 | $11,989,328 | Aug 11 | Revolution Studios | false |
| 159 | End of the Spear | - | - | - | $11,746,686 | 1,163 | $11,967,000 | Jan 20 | Rocky Mountain Pictures | false |
| 160 | Dave Chappelle's Block Party | - | - | - | $11,720,590 | 1,200 | $11,718,595 | Mar 3 | Rogue Pictures | false |
| 161 | The Last Kiss | - | - | - | $11,614,790 | 1,359 | $11,614,790 | Sep 15 | DreamWorks | false |
| 162 | Something New | - | - | - | $11,469,090 | 1,265 | $11,468,568 | Feb 3 | Focus Features | false |
| 163 | Material Girls | - | - | - | $11,449,638 | 1,509 | $11,449,638 | Aug 18 | Metro-Goldwyn-Mayer (MGM) | false |
| 164 | Bobby | - | - | - | $11,034,972 | 1,670 | $11,242,801 | Nov 17 | - | false |
| 165 | Black Christmas | - | - | - | $10,917,918 | 1,544 | $16,273,581 | Dec 25 | - | false |
| 166 | Mrs. Henderson Presents | - | - | - | $10,661,180 | 522 | $11,036,366 | Dec 9 | The Weinstein Company | false |
| 167 | Casanova | - | - | - | $10,579,075 | 1,011 | $11,304,403 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 168 | Magnificent Desolation: Walking on the Moon | - | - | - | $10,571,573 | 82 | $34,137,524 | Sep 23 | IMAX | false |
| 169 | Scoop | - | - | - | $10,526,261 | 541 | $10,525,717 | Jul 28 | Focus Features | false |
| 170 | The Producers | - | - | - | $10,134,990 | 978 | $19,398,532 | Dec 16 | Universal Pictures | false |
| 171 | Facing the Giants | - | - | - | $10,066,143 | 441 | $10,178,331 | Sep 29 | IDP Distribution | false |
| 172 | The Fountain | - | - | - | $9,930,941 | 1,472 | $10,144,010 | Nov 22 | Warner Bros. | false |
| 173 | Transamerica | - | - | - | $8,770,560 | 656 | $9,015,303 | Dec 2 | The Weinstein Company | false |
| 174 | The Nightmare Before Christmas 2006 3D Release | - | - | - | $8,686,272 | 168 | $8,700,869 | Oct 20 | Walt Disney Studios Motion Pictures | false |
| 175 | Tenacious D in the Pick of Destiny | - | - | - | $8,311,739 | 1,919 | $8,334,575 | Nov 22 | New Line Cinema | false |
| 176 | Hoot | - | - | - | $8,118,000 | 3,018 | $8,117,637 | May 5 | New Line Cinema | false |
| 177 | Good Night, and Good Luck. | - | - | - | $8,114,382 | 929 | $31,558,003 | Oct 7 | Warner Independent Pictures (WIP) | false |
| 178 | The Night Listener | - | - | - | $7,835,046 | 1,370 | $7,836,393 | Aug 4 | Miramax | false |
| 179 | Slither | - | - | - | $7,802,450 | 1,946 | $7,802,450 | Mar 31 | Universal Pictures | false |
| 180 | The Return | - | - | - | $7,750,613 | 1,986 | $7,749,851 | Nov 10 | Rogue Pictures | false |
| 181 | Doogal | - | - | - | $7,438,119 | 2,319 | $7,438,000 | Feb 24 | The Weinstein Company | false |
| 182 | A Good Year | - | - | - | $7,430,241 | 2,067 | $7,459,300 | Nov 10 | Twentieth Century Fox | false |
| 183 | All the King's Men | - | - | - | $7,221,458 | 1,520 | $7,221,458 | Sep 22 | Sony Pictures Entertainment (SPE) | false |
| 184 | American Dreamz | - | - | - | $7,191,830 | 1,500 | $7,191,830 | Apr 21 | Universal Pictures | false |
| 185 | Phat Girlz | - | - | - | $7,061,128 | 1,060 | $7,061,128 | Apr 7 | Fox Searchlight Pictures | false |
| 186 | Crossover | - | - | - | $7,009,668 | 1,023 | $7,009,668 | Sep 1 | Sony Pictures Entertainment (SPE) | false |
| 187 | Turistas | - | - | - | $6,947,433 | 1,572 | $7,027,762 | Dec 1 | Fox Atomic | false |
| 188 | Running Scared | - | - | - | $6,845,051 | 1,611 | $6,855,137 | Feb 24 | New Line Cinema | false |
| 189 | Running with Scissors | - | - | - | $6,754,898 | 586 | $7,022,827 | Oct 20 | Sony Pictures Entertainment (SPE) | false |
| 190 | Grandma's Boy | - | - | - | $6,090,172 | 2,016 | $6,090,172 | Jan 6 | Twentieth Century Fox | false |
| 191 | Basic Instinct 2 | - | - | - | $5,971,336 | 1,453 | $5,971,336 | Mar 31 | Sony Pictures Entertainment (SPE) | false |
| 192 | Wild Safari - A South African Adventure | - | - | - | $5,811,433 | 21 | $16,621,530 | Apr 8 | - | false |
| 193 | Wolf Creek | - | - | - | $5,626,960 | 1,761 | $16,188,180 | Dec 25 | - | false |
| 194 | A Scanner Darkly | - | - | - | $5,501,616 | 263 | $5,501,616 | Jul 7 | Warner Independent Pictures (WIP) | false |
| 195 | Roving Mars | - | - | - | $5,461,675 | 27 | $10,407,978 | Jan 27 | Walt Disney Studios Motion Pictures | false |
| 196 | For Your Consideration | - | - | - | $5,414,596 | 625 | $5,549,923 | Nov 17 | Warner Independent Pictures (WIP) | false |
| 197 | Pride & Prejudice | - | - | - | $5,140,796 | 1,335 | $38,405,088 | Nov 11 | Focus Features | false |
| 198 | The Three Burials of Melquiades Estrada | - | - | - | $4,996,040 | 356 | $5,027,684 | Dec 14 | Sony Pictures Classics | false |
| 199 | The World's Fastest Indian | - | - | - | $4,971,721 | 251 | $5,128,124 | Dec 7 | Magnolia Pictures | false |
| 200 | The Libertine | - | - | - | $4,790,603 | 819 | $4,835,065 | Nov 25 | The Weinstein Company | false |
