| Rank | Release Group
             | Worldwide | Domestic | % | Foreign | % | 
|---|
| 1 | Avatar | $2,743,577,587 | $749,766,139 | 27.3% | $1,993,811,448 | 72.7% | 
| 2 | Harry Potter and the Half-Blood Prince | $933,959,197 | $301,959,197 | 32.3% | $632,000,000 | 67.7% | 
| 3 | Ice Age: Dawn of the Dinosaurs | $886,686,817 | $196,573,705 | 22.2% | $690,113,112 | 77.8% | 
| 4 | Transformers: Revenge of the Fallen | $836,303,693 | $402,111,870 | 48.1% | $434,191,823 | 51.9% | 
| 5 | 2012 | $769,679,473 | $166,112,167 | 21.6% | $603,567,306 | 78.4% | 
| 6 | Up | $735,099,082 | $293,004,164 | 39.9% | $442,094,918 | 60.1% | 
| 7 | The Twilight Saga: New Moon | $709,827,462 | $296,623,634 | 41.8% | $413,203,828 | 58.2% | 
| 8 | Sherlock Holmes | $524,028,679 | $209,028,679 | 39.9% | $315,000,000 | 60.1% | 
| 9 | Angels & Demons | $485,930,816 | $133,375,846 | 27.4% | $352,554,970 | 72.6% | 
| 10 | The Hangover | $468,812,930 | $277,322,503 | 59.2% | $191,490,290 | 40.8% | 
| 11 | Alvin and the Chipmunks: The Squeakquel | $443,140,005 | $219,614,612 | 49.6% | $223,525,393 | 50.4% | 
| 12 | Night at the Museum: Battle of the Smithsonian | $413,106,170 | $177,243,721 | 42.9% | $235,862,449 | 57.1% | 
| 13 | Star Trek | $385,680,446 | $257,730,019 | 66.8% | $127,950,427 | 33.2% | 
| 14 | Monsters vs. Aliens | $381,509,870 | $198,351,526 | 52% | $183,158,344 | 48% | 
| 15 | X-Men Origins: Wolverine | $373,062,864 | $179,883,157 | 48.2% | $193,179,707 | 51.8% | 
| 16 | Terminator Salvation | $371,353,001 | $125,322,469 | 33.7% | $246,030,532 | 66.3% | 
| 17 | Fast & Furious | $360,364,265 | $155,064,265 | 43% | $205,300,000 | 57% | 
| 18 | Prince of Persia: The Sands of Time | $336,365,676 | $90,759,676 | 27% | $245,606,000 | 73% | 
| 19 | A Christmas Carol | $325,286,646 | $137,855,863 | 42.4% | $187,430,783 | 57.6% | 
| 20 | Inglourious Basterds | $321,455,689 | $120,540,719 | 37.5% | $200,914,970 | 62.5% | 
| 21 | The Proposal | $317,375,031 | $163,958,031 | 51.7% | $153,417,000 | 48.3% | 
| 22 | The Blind Side | $309,208,309 | $255,959,475 | 82.8% | $53,248,834 | 17.2% | 
| 23 | G.I. Joe: The Rise of Cobra | $302,469,017 | $150,201,498 | 49.7% | $152,267,519 | 50.3% | 
| 24 | G-Force | $292,817,841 | $119,436,770 | 40.8% | $173,381,071 | 59.2% | 
| 25 | This Is It | $267,983,588 | $72,091,016 | 26.9% | $195,892,572 | 73.1% | 
| 26 | The Princess and the Frog | $267,045,765 | $104,400,899 | 39.1% | $162,644,866 | 60.9% | 
| 27 | Cloudy with a Chance of Meatballs | $243,006,126 | $124,870,275 | 51.4% | $118,135,851 | 48.6% | 
| 28 | It's Complicated | $219,103,655 | $112,735,375 | 51.5% | $106,368,280 | 48.5% | 
| 29 | Public Enemies | $214,104,620 | $97,104,620 | 45.4% | $117,000,000 | 54.6% | 
| 30 | District 9 | $210,889,681 | $115,646,235 | 54.8% | $95,242,715 | 45.2% | 
| 31 | The Ugly Truth | $205,298,907 | $88,915,214 | 43.3% | $116,383,693 | 56.7% | 
| 32 | Paranormal Activity | $193,355,800 | $107,918,810 | 55.8% | $85,436,990 | 44.2% | 
| 33 | The Final Destination | $186,167,139 | $66,477,700 | 35.7% | $119,689,439 | 64.3% | 
| 34 | Watchmen | $185,382,813 | $107,509,799 | 58% | $77,873,014 | 42% | 
| 35 | Paul Blart: Mall Cop | $183,348,429 | $146,336,178 | 79.8% | $37,012,251 | 20.2% | 
| 36 | He's Just Not That Into You | $178,866,158 | $93,953,653 | 52.5% | $84,912,505 | 47.5% | 
| 37 | Couples Retreat | $171,844,840 | $109,204,945 | 63.5% | $62,639,895 | 36.5% | 
| 38 | Up in the Air | $166,842,739 | $83,823,381 | 50.2% | $83,019,358 | 49.8% | 
| 39 | Hannah Montana: The Movie | $155,545,279 | $79,576,189 | 51.2% | $75,969,090 | 48.8% | 
| 40 | The Taking of Pelham 123 | $150,166,126 | $65,452,312 | 43.6% | $84,713,814 | 56.4% | 
| 41 | Brüno | $138,805,831 | $60,054,530 | 43.3% | $78,751,301 | 56.7% | 
| 42 | 17 Again | $136,316,880 | $64,167,069 | 47.1% | $72,149,811 | 52.9% | 
| 43 | Julie & Julia | $129,540,522 | $94,125,426 | 72.7% | $35,415,096 | 27.3% | 
| 44 | The Fighter | $129,190,869 | $93,617,009 | 72.5% | $35,573,860 | 27.5% | 
| 45 | Law Abiding Citizen | $127,944,208 | $73,357,727 | 57.3% | $54,586,481 | 42.7% | 
| 46 | Coraline | $125,881,736 | $75,286,229 | 59.8% | $50,595,507 | 40.2% | 
| 47 | Surrogates | $122,444,772 | $38,577,772 | 31.5% | $83,867,000 | 68.5% | 
| 48 | Invictus | $122,233,971 | $37,491,364 | 30.7% | $84,742,607 | 69.3% | 
| 49 | Red Cliff II | $120,432,178 | - | - | $120,432,178 | 100% | 
| 50 | Hotel for Dogs | $117,252,578 | $73,034,460 | 62.3% | $44,218,118 | 37.7% | 
| 51 | Bride Wars | $115,375,850 | $58,715,510 | 50.9% | $56,660,340 | 49.1% | 
| 52 | Confessions of a Shopaholic | $108,394,089 | $44,277,350 | 40.8% | $64,116,739 | 59.2% | 
| 53 | Race to Witch Mountain | $106,387,141 | $67,172,594 | 63.1% | $39,214,547 | 36.9% | 
| 54 | Planet 51 | $105,647,102 | $42,194,060 | 39.9% | $63,453,042 | 60.1% | 
| 55 | The Girl with the Dragon Tattoo | $104,414,200 | $10,095,170 | 9.7% | $94,319,030 | 90.3% | 
| 56 | Zombieland | $102,392,080 | $75,590,286 | 73.8% | $26,801,794 | 26.2% | 
| 57 | Ghosts of Girlfriends Past | $102,366,815 | $55,250,026 | 54% | $47,116,789 | 46% | 
| 58 | The Time Traveler's Wife | $101,344,412 | $63,414,846 | 62.6% | $37,929,566 | 37.4% | 
| 59 | My Bloody Valentine | $100,734,718 | $51,545,952 | 51.2% | $49,188,766 | 48.8% | 
| 60 | Where the Wild Things Are | $100,140,096 | $77,233,467 | 77.1% | $22,906,629 | 22.9% | 
| 61 | Old Dogs | $96,753,696 | $49,492,060 | 51.2% | $47,261,636 | 48.8% | 
| 62 | My Sister's Keeper | $95,714,875 | $49,200,230 | 51.4% | $46,514,645 | 48.6% | 
| 63 | Green Zone | $94,882,549 | $35,053,660 | 36.9% | $59,828,889 | 63.1% | 
| 64 | The Lovely Bones | $93,621,340 | $44,114,232 | 47.1% | $49,507,108 | 52.9% | 
| 65 | Underworld: Rise of the Lycans | $92,158,961 | $45,802,315 | 49.7% | $46,356,646 | 50.3% | 
| 66 | I Love You, Man | $91,980,359 | $71,440,011 | 77.7% | $20,540,348 | 22.3% | 
| 67 | Friday the 13th | $91,509,154 | $65,002,019 | 71% | $26,507,135 | 29% | 
| 68 | Drag Me to Hell | $90,842,646 | $42,100,625 | 46.3% | $48,742,021 | 53.7% | 
| 69 | Madea Goes to Jail | $90,508,336 | $90,508,336 | 100% | - | - | 
| 70 | Rookies the Movie: Graduation | $88,055,243 | - | - | $88,055,243 | 100% | 
| 71 | State of Play | $87,812,371 | $37,017,955 | 42.2% | $50,794,416 | 57.8% | 
| 72 | Did You Hear About the Morgans? | $85,280,250 | $29,580,087 | 34.7% | $55,700,163 | 65.3% | 
| 73 | Duplicity | $78,176,181 | $40,572,825 | 51.9% | $37,603,356 | 48.1% | 
| 74 | Orphan | $77,912,251 | $41,596,251 | 53.4% | $36,316,000 | 46.6% | 
| 75 | The Haunting in Connecticut | $77,536,359 | $55,389,516 | 71.4% | $22,146,843 | 28.6% | 
| 76 | Fame | $77,211,836 | $22,455,510 | 29.1% | $54,756,326 | 70.9% | 
| 77 | The Unborn | $76,514,050 | $42,670,410 | 55.8% | $33,843,640 | 44.2% | 
| 78 | The Pink Panther 2 | $76,025,134 | $35,922,978 | 47.3% | $40,102,156 | 52.7% | 
| 79 | Obsessed | $73,830,347 | $68,261,644 | 92.5% | $5,568,703 | 7.5% | 
| 80 | Funny People | $71,585,235 | $51,855,045 | 72.4% | $19,730,190 | 27.6% | 
| 81 | Tidal Wave | $71,283,278 | - | - | $71,283,278 | 100% | 
| 82 | The Men Who Stare at Goats | $69,095,771 | $32,428,195 | 46.9% | $36,667,576 | 53.1% | 
| 83 | Land of the Lost | $68,777,554 | $49,438,370 | 71.9% | $19,339,184 | 28.1% | 
| 84 | Saw VI | $68,234,154 | $27,693,292 | 40.6% | $40,540,862 | 59.4% | 
| 85 | The Girl Who Played with Fire | $67,153,225 | $7,638,241 | 11.4% | $59,514,984 | 88.6% | 
| 86 | Precious | $63,649,529 | $47,566,524 | 74.7% | $16,083,005 | 25.3% | 
| 87 | Little Nicholas | $62,792,067 | - | - | $62,792,067 | 100% | 
| 88 | Year One | $62,357,900 | $43,337,279 | 69.5% | $19,020,621 | 30.5% | 
| 89 | The Imaginarium of Doctor Parnassus | $61,808,775 | $7,689,607 | 12.4% | $54,119,168 | 87.6% | 
| 90 | Ninja Assassin | $61,601,280 | $38,122,883 | 61.9% | $23,478,397 | 38.1% | 
| 91 | 500 Days of Summer | $60,722,734 | $32,391,374 | 53.3% | $28,331,360 | 46.7% | 
| 92 | 3 Idiots | $60,262,836 | $6,532,874 | 10.8% | $53,729,962 | 89.2% | 
| 93 | The International | $60,253,843 | $25,450,527 | 42.2% | $34,803,316 | 57.8% | 
| 94 | Aliens in the Attic | $57,881,056 | $25,200,412 | 43.5% | $32,680,644 | 56.5% | 
| 95 | Vicky the Viking | $56,390,258 | - | - | $56,390,258 | 100% | 
| 96 | Under the Sea 3D | $55,902,624 | $36,262,926 | 64.9% | $19,639,698 | 35.1% | 
| 97 | Dragonball Evolution | $55,720,772 | $9,362,785 | 16.8% | $46,357,987 | 83.2% | 
| 98 | Nine | $54,004,950 | $19,676,965 | 36.4% | $34,327,985 | 63.6% | 
| 99 | Arthur and the Revenge of Maltazard | $52,377,611 | - | - | $52,377,611 | 100% | 
| 100 | Take Off | $52,141,043 | - | - | $52,141,043 | 100% | 
| 101 | Pokémon: Arceus and the Jewel of Life | $52,119,081 | - | - | $52,119,081 | 100% | 
| 102 | I Can Do Bad All by Myself | $51,733,921 | $51,733,921 | 100% | - | - | 
| 103 | Coco Before Chanel | $50,812,934 | $6,113,834 | 12% | $44,699,100 | 88% | 
| 104 | One Piece: Strong World | $49,271,461 | - | - | $49,271,461 | 100% | 
| 105 | Push | $48,858,618 | $31,811,527 | 65.1% | $17,047,091 | 34.9% | 
| 106 | 9 | $48,428,063 | $31,749,894 | 65.6% | $16,678,169 | 34.4% | 
| 107 | 20th Century Boys 3: Redemption | $48,397,818 | - | - | $48,397,818 | 100% | 
| 108 | The Fourth Kind | $47,709,193 | $25,486,040 | 53.4% | $22,223,153 | 46.6% | 
| 109 | Crazy Heart | $47,405,566 | $39,464,306 | 83.2% | $7,941,260 | 16.8% | 
| 110 | Hachi: A Dog's Tale | $46,748,131 | - | - | $46,748,131 | 100% | 
| 111 | Fantastic Mr. Fox | $46,471,023 | $21,002,919 | 45.2% | $25,468,104 | 54.8% | 
| 112 | Rabbit Without Ears 2 | $46,439,905 | - | - | $46,439,905 | 100% | 
| 113 | The Last House on the Left | $45,289,053 | $32,752,215 | 72.3% | $12,536,838 | 27.7% | 
| 114 | The Spy Next Door | $45,236,543 | $24,307,086 | 53.7% | $20,929,457 | 46.3% | 
| 115 | Nodame Cantabile: The Movie II | $44,879,450 | - | - | $44,879,450 | 100% | 
| 116 | Notorious | $44,420,316 | $36,843,682 | 82.9% | $7,576,485 | 17.1% | 
| 117 | The Girl Who Kicked the Hornet's Nest | $44,276,335 | $5,190,196 | 11.7% | $39,086,139 | 88.3% | 
| 118 | Brothers | $43,474,578 | $28,544,157 | 65.7% | $14,930,421 | 34.3% | 
| 119 | The Informant! | $41,771,168 | $33,316,821 | 79.8% | $8,454,347 | 20.2% | 
| 120 | The Uninvited | $41,633,384 | $28,596,818 | 68.7% | $13,036,566 | 31.3% | 
| 121 | Toy Story 2009 Re-release | $41,258,298 | $30,702,446 | 74.4% | $10,555,852 | 25.6% | 
| 122 | Evangelion: 2.0 You Can (Not) Advance | $41,162,041 | $133,640 | 0.3% | $41,028,401 | 99.7% | 
| 123 | The Concert | $41,146,351 | $657,986 | 1.6% | $40,488,365 | 98.4% | 
| 124 | Gamer | $40,828,540 | $20,534,907 | 50.3% | $20,293,633 | 49.7% | 
| 125 | All About Steve | $40,105,542 | $33,862,903 | 84.4% | $6,242,639 | 15.6% | 
| 126 | Astro Boy | $39,886,986 | $19,551,067 | 49% | $20,335,919 | 51% | 
| 127 | Detective Conan: The Raven Chaser | $39,664,359 | - | - | $39,664,359 | 100% | 
| 128 | Agora | $39,457,342 | $619,423 | 1.6% | $38,837,919 | 98.4% | 
| 129 | Halloween II | $39,421,467 | $33,392,973 | 84.7% | $6,028,494 | 15.3% | 
| 130 | Cirque du Freak: The Vampire's Assistant | $39,291,383 | $13,869,515 | 35.3% | $25,421,868 | 64.7% | 
| 131 | Jeon Woochi | $38,681,926 | - | - | $38,681,926 | 100% | 
| 132 | The Soloist | $38,332,994 | $31,720,158 | 82.7% | $6,612,836 | 17.3% | 
| 133 | Amalfi: Rewards of the Goddess | $37,840,539 | - | - | $37,840,539 | 100% | 
| 134 | Broken Embraces | $37,472,507 | $5,014,305 | 13.4% | $32,458,202 | 86.6% | 
| 135 | Brooklyn's Finest | $36,440,201 | $27,163,593 | 74.5% | $9,276,608 | 25.5% | 
| 136 | The Boat That Rocked | $36,348,784 | $8,017,917 | 22.1% | $28,330,867 | 77.9% | 
| 137 | Love Happens | $36,088,028 | $22,965,110 | 63.6% | $13,122,918 | 36.4% | 
| 138 | Whatever Works | $36,020,534 | $5,306,706 | 14.7% | $30,713,828 | 85.3% | 
| 139 | The Secret in Their Eyes | $35,079,650 | $6,391,436 | 18.2% | $28,688,214 | 81.8% | 
| 140 | Crank: High Voltage | $34,572,541 | $13,684,249 | 39.6% | $20,888,292 | 60.4% | 
| 141 | Gokusen: The Movie | $34,117,482 | - | - | $34,117,482 | 100% | 
| 142 | The Box | $33,333,531 | $15,051,977 | 45.2% | $18,281,554 | 54.8% | 
| 143 | LOL (Laughing Out Loud) | $32,764,784 | - | - | $32,764,784 | 100% | 
| 144 | Fighting | $32,482,728 | $23,091,010 | 71.1% | $9,391,718 | 28.9% | 
| 145 | The Invention of Lying | $32,406,507 | $18,451,251 | 56.9% | $13,955,256 | 43.1% | 
| 146 | April Bride | $32,112,343 | - | - | $32,112,343 | 100% | 
| 147 | Jennifer's Body | $31,556,061 | $16,204,793 | 51.4% | $15,351,268 | 48.6% | 
| 148 | Dance Flick | $31,439,140 | $25,662,155 | 81.6% | $5,776,985 | 18.4% | 
| 149 | A Serious Man | $31,430,334 | $9,228,768 | 29.4% | $22,201,566 | 70.6% | 
| 150 | The Stepfather | $31,198,531 | $29,062,561 | 93.2% | $2,135,970 | 6.8% | 
| 151 | Yatterman | $30,365,792 | - | - | $30,365,792 | 100% | 
| 152 | Natale a Beverly Hills | $29,976,481 | - | - | $29,976,481 | 100% | 
| 153 | Crows Zero II | $29,893,636 | - | - | $29,893,636 | 100% | 
| 154 | 20th Century Boys 2: The Last Hope | $29,502,213 | - | - | $29,502,213 | 100% | 
| 155 | The Young Victoria | $29,181,829 | $11,001,272 | 37.7% | $18,180,557 | 62.3% | 
| 156 | New in Town | $29,010,817 | $16,734,283 | 57.7% | $12,276,534 | 42.3% | 
| 157 | The Unbroken | $29,000,322 | - | - | $29,000,322 | 100% | 
| 158 | Shorts | $28,972,508 | $20,919,166 | 72.2% | $8,053,342 | 27.8% | 
| 159 | Pope Joan | $28,748,076 | - | - | $28,748,076 | 100% | 
| 160 | Case 39 | $28,190,603 | $13,261,851 | 47% | $14,928,752 | 53% | 
| 161 | Recep Ivedik 2 | $27,699,692 | - | - | $27,699,692 | 100% | 
| 162 | The Road | $27,639,579 | $8,117,000 | 29.4% | $19,522,579 | 70.6% | 
| 163 | Sorority Row | $27,206,120 | $11,965,282 | 44% | $15,240,838 | 56% | 
| 164 | Observe and Report | $26,973,554 | $24,007,324 | 89% | $2,966,230 | 11% | 
| 165 | An Education | $26,096,852 | $12,574,914 | 48.2% | $13,521,938 | 51.8% | 
| 166 | Coco | $25,593,707 | - | - | $25,593,707 | 100% | 
| 167 | Doraemon the Movie: The New Records of Nobita's Spaceblazer | $25,422,212 | - | - | $25,422,212 | 100% | 
| 168 | Mt. Tsurugidake | $25,134,437 | - | - | $25,134,437 | 100% | 
| 169 | A Single Man | $24,964,890 | $9,176,000 | 36.8% | $15,788,890 | 63.2% | 
| 170 | Kaiji: The Ultimate Gambler | $24,709,016 | - | - | $24,709,016 | 100% | 
| 171 | If I Were You 2 | $24,415,116 | - | - | $24,415,116 | 100% | 
| 172 | I Give My First Love to You | $24,051,386 | - | - | $24,051,386 | 100% | 
| 173 | Mao's Last Dancer | $23,914,731 | $4,817,770 | 20.1% | $19,096,961 | 79.9% | 
| 174 | Dark Planet | $23,772,559 | - | - | $23,772,559 | 100% | 
| 175 | Jonas Brothers: The 3D Concert Experience | $23,186,960 | $19,162,740 | 82.6% | $4,024,220 | 17.4% | 
| 176 | Imagine That | $22,985,194 | $16,123,323 | 70.1% | $6,861,871 | 29.9% | 
| 177 | Armored | $22,942,221 | $15,988,876 | 69.7% | $6,953,345 | 30.3% | 
| 178 | A Perfect Getaway | $22,938,329 | $15,515,460 | 67.6% | $7,422,869 | 32.4% | 
| 179 | Dorian Gray | $22,873,653 | - | - | $22,873,653 | 100% | 
| 180 | Men in the City | $22,420,615 | - | - | $22,420,615 | 100% | 
| 181 | Neuilly Yo Mama! | $22,243,482 | - | - | $22,243,482 | 100% | 
| 182 | OSS 117: Lost in Rio | $21,924,245 | $89,375 | 0.4% | $21,834,870 | 99.6% | 
| 183 | The Rebound | $21,791,288 | - | - | $21,791,288 | 100% | 
| 184 | My Girlfriend Is an Agent | $21,056,256 | - | - | $21,056,256 | 100% | 
| 185 | Black Lightning | $20,984,902 | - | - | $20,984,902 | 100% | 
| 186 | Love Aaj Kal | $20,794,985 | $2,430,083 | 11.7% | $18,364,902 | 88.3% | 
| 187 | I Love You Phillip Morris | $20,768,906 | $2,037,459 | 9.8% | $18,731,447 | 90.2% | 
| 188 | Pandemic | $20,712,567 | - | - | $20,712,567 | 100% | 
| 189 | Pandorum | $20,648,328 | $10,330,853 | 50% | $10,317,475 | 50% | 
| 190 | My Life in Ruins | $20,455,482 | $8,665,206 | 42.4% | $11,790,276 | 57.6% | 
| 191 | Cado dalle nubi | $20,123,466 | - | - | $20,123,466 | 100% | 
| 192 | Solomon Kane | $19,652,185 | - | - | $19,652,185 | 100% | 
| 193 | Amelia | $19,643,086 | $14,246,488 | 72.5% | $5,396,598 | 27.5% | 
| 194 | Drop | $19,611,028 | - | - | $19,611,028 | 100% | 
| 195 | High Security Vacation | $19,487,557 | - | - | $19,487,557 | 100% | 
| 196 | Kamen Rider Decade: All Riders vs. Dai-Shocker | $19,418,091 | - | - | $19,418,091 | 100% | 
| 197 | The White Ribbon | $19,340,126 | $2,222,862 | 11.5% | $17,117,264 | 88.5% | 
| 198 | Ballad | $19,328,678 | - | - | $19,328,678 | 100% | 
| 199 | Cell 211 | $19,300,483 | - | - | $19,300,483 | 100% | 
| 200 | Taras Bulba | $18,874,808 | - | - | $18,874,808 | 100% |