| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Ghostbusters: Afterlife | $63,314,511 | $44,008,406 | 69.5% | $19,306,105 | 30.5% | 4,315 | 1 | Sony Pictures Releasing | - | false |
| 2 | Eternals | $17,818,082 | $11,084,855 | 62.2% | $6,733,227 | 37.8% | 4,055 | 3 | Walt Disney Studios Motion Pictures | - | false |
| 3 | Encanto | $13,360,779 | - | - | - | - | 3,980 | 1 | Walt Disney Studios Motion Pictures | - | false |
| 4 | Clifford the Big Red Dog | $12,596,384 | $8,121,777 | 64.5% | $4,474,607 | 35.5% | 3,628 | 3 | Paramount Pictures | - | false |
| 5 | King Richard | $8,073,542 | $5,406,033 | 67% | $2,667,509 | 33% | 3,302 | 1 | Warner Bros. | - | false |
| 6 | House of Gucci | $7,590,504 | - | - | - | - | 3,441 | 1 | United Artists Releasing | - | false |
| 7 | Dune: Part One | $4,944,986 | $3,174,916 | 64.2% | $1,770,070 | 35.8% | 2,467 | 5 | Warner Bros. | - | false |
| 8 | No Time to Die | $4,390,641 | $2,765,272 | 63% | $1,625,369 | 37% | 2,407 | 7 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 9 | Venom: Let There Be Carnage | $4,237,025 | $2,910,607 | 68.7% | $1,326,418 | 31.3% | 2,538 | 8 | Sony Pictures Releasing | - | false |
| 10 | Resident Evil: Welcome to Raccoon City | $3,531,339 | - | - | - | - | 2,803 | 1 | Screen Gems | - | false |
| 11 | The French Dispatch | $1,544,858 | $1,000,091 | 64.7% | $544,767 | 35.3% | 805 | 5 | Searchlight Pictures | - | false |
| 12 | Belfast | $1,513,825 | $945,425 | 62.4% | $568,400 | 37.6% | 1,128 | 2 | Focus Features | - | false |
| 13 | Ron's Gone Wrong | $1,338,412 | $942,066 | 70.4% | $396,346 | 29.6% | 1,520 | 5 | 20th Century Studios | - | false |
| 14 | Spencer | $1,016,639 | $709,589 | 69.8% | $307,050 | 30.2% | 954 | 3 | Neon | - | false |
| 15 | Antlers | $488,262 | $371,644 | 76.1% | $116,618 | 23.9% | 690 | 4 | Searchlight Pictures | - | false |
| 16 | My Hero Academia: World Heroes' Mission | $391,930 | $268,984 | 68.6% | $122,946 | 31.4% | 382 | 4 | FUNimation Entertainment | - | false |
| 17 | Sooryavanshi | $362,958 | $244,761 | 67.4% | $118,197 | 32.6% | 215 | 3 | Reliance Entertainment | - | false |
| 18 | Last Night in Soho | $319,875 | $234,110 | 73.2% | $85,765 | 26.8% | 389 | 4 | Focus Features | - | false |
| 19 | L'Arracheuse de temps | $301,372 | $188,790 | 62.6% | $112,582 | 37.4% | 68 | 1 | Entertainment One | - | false |
| 20 | Halloween Kills | $262,970 | $212,880 | 81% | $50,090 | 19% | 627 | 6 | Universal Pictures | - | false |
| 21 | The Addams Family 2 | $237,902 | $168,215 | 70.7% | $69,687 | 29.3% | 507 | 8 | United Artists Releasing | - | false |
| 22 | India Sweets and Spices | $236,984 | $170,629 | 72% | $66,355 | 28% | 343 | 1 | Bleecker Street Media | - | false |
| 23 | C'mon C'mon | $234,968 | $134,447 | - | - | - | 5 | 1 | A24 | - | true |
| 24 | Anita | $189,536 | $102,766 | 54.2% | $86,770 | 45.8% | 15 | 2 | CMC Pictures | - | false |
| 25 | The Battle at Lake Changjin | $182,713 | $105,768 | 57.9% | $76,945 | 42.1% | 20 | 1 | CMC Pictures | - | false |
| 26 | Julia | $101,951 | $42,335 | 41.5% | $59,616 | 58.5% | 288 | 2 | Sony Pictures Classics | - | false |
| 27 | For the Love of Money | $74,669 | - | - | - | - | 519 | 1 | Freestyle Releasing | - | false |
| 28 | Shang-Chi and the Legend of the Ten Rings | $68,886 | $48,964 | 71.1% | $19,922 | 28.9% | 120 | 12 | Walt Disney Studios Motion Pictures | - | false |
| 29 | The Last Duel | $68,507 | $42,436 | 61.9% | $26,071 | 38.1% | 165 | 6 | 20th Century Studios | - | false |
| 30 | The First Wave | $62,376 | $60,511 | 97% | $1,865 | 3% | 11 | 1 | Neon | - | false |
| 31 | Kurt Vonnegut: Unstuck in Time | $41,863 | $27,427 | 65.5% | $14,436 | 34.5% | 69 | 1 | IFC Films | - | false |
| 32 | The Youngest Evangelist | $35,750 | $27,300 | 76.4% | $8,450 | 23.6% | 233 | 1 | Atlas Distribution Company | - | false |
| 33 | Free Guy | $27,986 | $17,880 | 63.9% | $10,106 | 36.1% | 65 | 15 | 20th Century Studios | - | false |
| 34 | A Revision | $22,657 | $14,483 | 63.9% | $8,174 | 36.1% | 38 | 3 | Entertainment One | - | false |
| 35 | The Rescue | $13,934 | $10,056 | 72.2% | $3,878 | 27.8% | 25 | 7 | Greenwich Entertainment | - | false |
| 36 | Bad Luck Banging or Loony Porn | $12,087 | $7,672 | 63.5% | $4,415 | 36.5% | 2 | 1 | Magnolia Pictures | - | false |
| 37 | I Was a Simple Man | $10,217 | $7,525 | 73.6% | $2,692 | 26.4% | 6 | 1 | Strand Releasing | - | false |
| 38 | Jungle Cruise | $8,000 | $8,000 | - | - | - | 38 | 17 | Walt Disney Studios Motion Pictures | - | true |
| 39 | Unoponchash Batash | $6,033 | $4,206 | 69.7% | $1,827 | 30.3% | 15 | 1 | Swapna Scarecrow | - | false |
| 40 | The Feast | $6,015 | $3,620 | 60.2% | $2,395 | 39.8% | 22 | 1 | IFC Films | - | false |
| 41 | The Incredibly True Adventure of Two Girls in Love 2021 Re-release | $1,802 | - | - | - | - | 1 | 1 | Strand Releasing | - | false |
| 42 | Cicada | $1,698 | $1,447 | 85.2% | $251 | 14.8% | 2 | 4 | Strand Releasing | - | false |
| 43 | I'm Your Man | $1,286 | $763 | 59.3% | $523 | 40.7% | 3 | 9 | Bleecker Street Media | - | false |
| 44 | Christmas vs. The Walters | $1,077 | $913 | 84.8% | $164 | 15.2% | 7 | 3 | Safier Entertainment | - | false |
| 45 | Mass | $946 | $778 | 82.2% | $168 | 17.8% | 37 | 7 | Bleecker Street Media | - | false |
| 46 | The Beta Test | $913 | $638 | 69.9% | $275 | 30.1% | 6 | 3 | IFC Films | - | false |
| 47 | Breathless 2021 Re-release | $728 | $728 | 100% | $0 | - | 1 | 9 | Rialto Pictures | - | false |
| 48 | Wife of a Spy | $536 | $536 | 100% | $0 | - | 1 | 10 | Kino Lorber | - | false |
| 49 | Luzzu | $293 | $186 | 63.5% | $107 | 36.5% | 2 | 6 | Kino Lorber | - | false |
| 50 | Little Girl | $201 | $103 | 51.2% | $98 | 48.8% | 1 | 10 | Music Box Films | - | false |
| 51 | The Laws of the Universe: The Age of Elohim | $94 | $62 | 66% | $32 | 34% | 1 | 5 | Freestyle Releasing | - | false |
