| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | The Suicide Squad | $35,134,747 | $26,205,415 | 74.6% | $8,929,332 | 25.4% | 4,002 | 1 | Warner Bros. | - | false |
| 2 | Jungle Cruise | $23,518,100 | $15,818,590 | 67.3% | $7,699,510 | 32.7% | 4,310 | 2 | Walt Disney Studios Motion Pictures | - | false |
| 3 | Old | $6,174,495 | $4,115,605 | 66.6% | $2,058,890 | 33.4% | 3,138 | 3 | Universal Pictures | - | false |
| 4 | Black Widow | $5,847,747 | $3,928,252 | 67.2% | $1,919,495 | 32.8% | 3,100 | 5 | Walt Disney Studios Motion Pictures | - | false |
| 5 | Stillwater | $4,102,625 | $2,828,690 | 69% | $1,273,935 | 31% | 2,611 | 2 | Focus Features | - | false |
| 6 | The Green Knight | $4,003,128 | $2,597,185 | 64.9% | $1,405,943 | 35.1% | 2,798 | 2 | A24 | - | false |
| 7 | Space Jam: A New Legacy | $3,796,957 | $2,433,878 | 64.1% | $1,363,079 | 35.9% | 2,869 | 4 | Warner Bros. | - | false |
| 8 | Snake Eyes | $2,527,233 | $1,682,463 | 66.6% | $844,770 | 33.4% | 2,080 | 3 | Paramount Pictures | - | false |
| 9 | Escape Room: Tournament of Champions | $2,032,468 | $1,303,320 | 64.1% | $729,148 | 35.9% | 1,303 | 4 | Sony Pictures Releasing | - | false |
| 10 | F9: The Fast Saga | $1,744,920 | $1,200,620 | 68.8% | $544,300 | 31.2% | 1,715 | 7 | Universal Pictures | - | false |
| 11 | The Boss Baby 2: Family Business | $1,215,580 | $750,090 | 61.7% | $465,490 | 38.3% | 1,405 | 6 | Universal Pictures | - | false |
| 12 | The Forever Purge | $748,030 | $526,350 | 70.4% | $221,680 | 29.6% | 779 | 6 | Universal Pictures | - | false |
| 13 | A Quiet Place Part II | $506,489 | $323,758 | 63.9% | $182,731 | 36.1% | 520 | 11 | Paramount Pictures | - | false |
| 14 | Nine Days | $382,509 | $232,509 | 60.8% | $150,000 | 39.2% | 443 | 2 | Sony Pictures Classics | - | false |
| 15 | Roadrunner: A Film About Anthony Bourdain | $266,880 | $176,225 | 66% | $90,655 | 34% | 268 | 4 | Focus Features | - | false |
| 16 | The Conjuring: The Devil Made Me Do It | $253,768 | $170,063 | 67% | $83,705 | 33% | 100 | 10 | Warner Bros. | - | false |
| 17 | Cruella | $203,441 | $135,996 | 66.8% | $67,445 | 33.2% | 148 | 11 | Walt Disney Studios Motion Pictures | - | false |
| 18 | Pig | $175,588 | $103,551 | 59% | $72,037 | 41% | 170 | 4 | Neon | - | false |
| 19 | Hitman's Wife's Bodyguard | $133,012 | $82,871 | 62.3% | $50,141 | 37.7% | 179 | 9 | Lionsgate | - | false |
| 20 | Ailey | $81,079 | $47,236 | 58.3% | $33,843 | 41.7% | 88 | 3 | Neon | - | false |
| 21 | In the Heights | $71,835 | $45,330 | 63.1% | $26,505 | 36.9% | 191 | 9 | Warner Bros. | - | false |
| 22 | Peter Rabbit 2: The Runaway | $61,191 | $61,191 | 100% | $0 | - | 119 | 9 | Sony Pictures Releasing | - | false |
| 23 | Once I Was Engaged | $53,045 | $30,261 | 57% | $22,784 | 43% | 30 | 4 | Excel Entertainment | - | false |
| 24 | Dream Horse | $47,684 | $24,196 | 50.7% | $23,488 | 49.3% | 56 | 12 | Bleecker Street Media | - | false |
| 25 | Zola | $42,919 | $25,745 | 60% | $17,174 | 40% | 35 | 7 | A24 | - | false |
| 26 | Swan Song | $42,124 | $26,855 | 63.8% | $15,269 | 36.2% | 37 | 1 | Magnolia Pictures | - | false |
| 27 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $37,035 | $23,867 | 64.4% | $13,168 | 35.6% | 42 | 7 | Searchlight Pictures | - | false |
| 28 | 12 Mighty Orphans | $30,430 | $18,376 | 60.4% | $12,054 | 39.6% | 42 | 9 | Sony Pictures Releasing | - | false |
| 29 | Joe Bell | $29,564 | $19,353 | 65.5% | $10,211 | 34.5% | 113 | 3 | Roadside Attractions | - | false |
| 30 | Queen Bees | $24,435 | $14,113 | 57.8% | $10,322 | 42.2% | 47 | 9 | Gravitas Ventures | - | false |
| 31 | John and the Hole | $22,162 | $16,658 | 75.2% | $5,504 | 24.8% | 42 | 1 | IFC Films | - | false |
| 32 | Raya and the Last Dragon | $18,188 | $14,039 | 77.2% | $4,149 | 22.8% | 24 | 23 | Walt Disney Studios Motion Pictures | - | false |
| 33 | Bring Your Own Brigade | $13,375 | $8,334 | 62.3% | $5,041 | 37.7% | 27 | 1 | Paramount Pictures | - | false |
| 34 | Witnesses | $12,546 | $5,554 | 44.3% | $6,992 | 55.7% | 10 | 10 | Purdie Distribution | - | false |
| 35 | CatVideoFest 2021 | $12,484 | - | - | - | - | 12 | 3 | Oscilloscope | - | false |
| 36 | Without Getting Killed or Caught | $11,391 | - | - | - | - | 6 | 3 | mTuckman Media | - | false |
| 37 | Even in Dreams | $8,264 | $6,368 | 77.1% | $1,896 | 22.9% | 5 | 1 | Purdie Distribution | - | false |
| 38 | Sabaya | $6,792 | - | - | - | - | 14 | 2 | MTV Documentary Films | - | false |
| 39 | Never Gonna Snow Again | $4,812 | - | - | - | - | 8 | 2 | Kino Lorber | - | false |
| 40 | The Swimming Pool 2021 Re-release | $4,744 | $2,497 | 52.6% | $2,247 | 47.4% | 3 | 13 | Rialto Distribution | - | false |
| 41 | The Loneliest Whale: The Search for 52 | $3,458 | $1,659 | 48% | $1,799 | 52% | 20 | 5 | Bleecker Street Media | - | false |
| 42 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $3,398 | $3,398 | 100% | $0 | - | 11 | 16 | FUNimation Entertainment | - | false |
| 43 | Lorelei | $2,515 | - | - | - | - | 5 | 2 | Freestyle Releasing | - | false |
| 44 | Summertime | $2,414 | - | - | - | - | 14 | 5 | Good Deed Entertainment | - | false |
| 45 | Lydia Lunch: The War Is Never Over | $2,316 | - | - | - | - | 4 | 7 | Kino Lorber | - | false |
| 46 | The Truffle Hunters | $2,245 | $1,423 | 63.4% | $822 | 36.6% | 4 | 23 | Sony Pictures Classics | - | false |
| 47 | Mandibles | $1,968 | $1,022 | 51.9% | $946 | 48.1% | 6 | 3 | Magnet Releasing | - | false |
| 48 | Mama Weed | $1,276 | $981 | 76.9% | $295 | 23.1% | 3 | 4 | Music Box Films | - | false |
| 49 | I Carry You with Me | $1,255 | $831 | 66.2% | $424 | 33.8% | 4 | 7 | Sony Pictures Classics | - | false |
| 50 | The Incredible 25th Year of Mitzi Bearclaw | $1,160 | $896 | 77.2% | $264 | 22.8% | 1 | 26 | Indican Pictures | - | false |
| 51 | Can You Bring It: Bill T. Jones and D-Man in the Waters | $1,017 | - | - | - | - | 3 | 4 | Kino Lorber | - | false |
| 52 | Enemies of the State | $784 | $400 | 51% | $384 | 49% | 5 | 2 | IFC Films | - | false |
| 53 | Werewolves Within | $628 | $459 | 73.1% | $169 | 26.9% | 11 | 7 | IFC Films | - | false |
| 54 | No Ordinary Man | $515 | - | - | - | - | 3 | 4 | Oscilloscope | - | false |
| 55 | Casanova, Last Love | $288 | $195 | 67.7% | $93 | 32.3% | 2 | 5 | Cohen Media Group | - | false |
| 56 | The Red Circle 2021 Re-release | $190 | - | - | - | - | 1 | 7 | Rialto Pictures | - | false |
| 57 | Shiva Baby | $69 | $69 | 100% | $0 | - | 1 | 19 | Utopia | - | false |
