| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Jungle Cruise | $49,624,454 | $35,018,731 | 70.6% | $14,605,723 | 29.4% | 4,310 | 1 | Walt Disney Studios Motion Pictures | - | false |
| 2 | Space Jam: A New Legacy | $11,808,175 | $4,325,673 | - | - | - | 3,501 | 3 | Warner Bros. | - | true |
| 3 | Old | $10,529,890 | $6,862,425 | 65.2% | $3,667,465 | 34.8% | 3,379 | 2 | Universal Pictures | - | false |
| 4 | Black Widow | $9,710,922 | $6,471,183 | 66.6% | $3,239,739 | 33.4% | 3,360 | 4 | Walt Disney Studios Motion Pictures | - | false |
| 5 | The Green Knight | $9,571,727 | $6,790,917 | 71% | $2,780,810 | 29% | 2,790 | 1 | A24 | - | false |
| 6 | Stillwater | $7,140,070 | $5,188,150 | 72.7% | $1,951,920 | 27.3% | 2,531 | 1 | Focus Features | - | false |
| 7 | Snake Eyes | $6,094,428 | $4,064,394 | 66.7% | $2,030,034 | 33.3% | 3,540 | 2 | Paramount Pictures | - | false |
| 8 | F9: The Fast Saga | $3,909,530 | $2,663,925 | 68.1% | $1,245,605 | 31.9% | 2,348 | 6 | Universal Pictures | - | false |
| 9 | Escape Room: Tournament of Champions | $3,438,638 | $2,236,652 | 65% | $1,201,986 | 35% | 2,086 | 3 | Sony Pictures Releasing | - | false |
| 10 | The Boss Baby 2: Family Business | $2,253,475 | $1,377,390 | 61.1% | $876,085 | 38.9% | 1,865 | 5 | Universal Pictures | - | false |
| 11 | The Forever Purge | $1,659,935 | $1,143,285 | 68.9% | $516,650 | 31.1% | 1,166 | 5 | Universal Pictures | - | false |
| 12 | A Quiet Place Part II | $936,020 | $615,779 | 65.8% | $320,241 | 34.2% | 779 | 10 | Paramount Pictures | - | false |
| 13 | Roadrunner: A Film About Anthony Bourdain | $570,925 | $365,995 | 64.1% | $204,930 | 35.9% | 537 | 3 | Focus Features | - | false |
| 14 | Cruella | $527,117 | $340,242 | 64.6% | $186,875 | 35.4% | 235 | 10 | Walt Disney Studios Motion Pictures | - | false |
| 15 | Pig | $392,467 | $240,812 | 61.4% | $151,655 | 38.6% | 336 | 3 | Neon | - | false |
| 16 | Joe Bell | $274,310 | $178,495 | 65.1% | $95,815 | 34.9% | 1,053 | 2 | Roadside Attractions | - | false |
| 17 | Hitman's Wife's Bodyguard | $248,926 | $156,391 | 62.8% | $92,535 | 37.2% | 260 | 8 | Lionsgate | - | false |
| 18 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $88,835 | $51,975 | 58.5% | $36,860 | 41.5% | 85 | 6 | Searchlight Pictures | - | false |
| 19 | Zola | $86,308 | $55,262 | 64% | $31,046 | 36% | 114 | 6 | A24 | - | false |
| 20 | Peter Rabbit 2: The Runaway | $84,516 | $84,516 | 100% | $0 | - | 180 | 8 | Sony Pictures Releasing | - | false |
| 21 | Once I Was Engaged | $41,095 | $17,345 | 42.2% | $23,750 | 57.8% | 30 | 3 | Excel Entertainment | - | false |
| 22 | Raya and the Last Dragon | $38,405 | $26,202 | 68.2% | $12,203 | 31.8% | 30 | 22 | Walt Disney Studios Motion Pictures | - | false |
| 23 | Spirit Untamed | $36,630 | $21,825 | 59.6% | $14,805 | 40.4% | 738 | 9 | Universal Pictures | - | false |
| 24 | 12 Mighty Orphans | $33,880 | $25,350 | 74.8% | $8,530 | 25.2% | 50 | 8 | Sony Pictures Releasing | - | false |
| 25 | Queen Bees | $28,133 | $15,605 | 55.5% | $12,528 | 44.5% | 47 | 8 | Gravitas Ventures | - | false |
| 26 | Nine Days | $25,597 | $15,700 | 61.3% | $9,897 | 38.7% | 4 | 1 | Sony Pictures Classics | - | false |
| 27 | Without Getting Killed or Caught | $17,111 | $14,430 | - | - | - | 7 | 2 | mTuckman Media | - | true |
| 28 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $16,934 | $9,069 | 53.6% | $7,865 | 46.4% | 21 | 15 | FUNimation Entertainment | - | false |
| 29 | Witnesses | $13,911 | $5,787 | 41.6% | $8,124 | 58.4% | 12 | 9 | Purdie Distribution | - | false |
| 30 | Settlers | $13,358 | $8,646 | 64.7% | $4,712 | 35.3% | 7 | 2 | IFC Films | - | false |
| 31 | The Truffle Hunters | $11,564 | $8,694 | 75.2% | $2,870 | 24.8% | 14 | 22 | Sony Pictures Classics | - | false |
| 32 | Lorelei | $10,127 | - | - | - | - | 11 | 1 | Freestyle Releasing | - | false |
| 33 | Ailey | $10,021 | $4,857 | 48.5% | $5,164 | 51.5% | 2 | 2 | Neon | - | false |
| 34 | Enemies of the State | $7,290 | $4,142 | 56.8% | $3,148 | 43.2% | 13 | 1 | IFC Films | - | false |
| 35 | The Swimming Pool 2021 Re-release | $5,216 | $2,948 | 56.5% | $2,268 | 43.5% | 3 | 12 | Rialto Distribution | - | false |
| 36 | I Carry You with Me | $5,212 | $2,322 | 44.6% | $2,890 | 55.4% | 18 | 6 | Sony Pictures Classics | - | false |
| 37 | The Loneliest Whale: The Search for 52 | $4,728 | $2,742 | 58% | $1,986 | 42% | 20 | 4 | Bleecker Street Media | - | false |
| 38 | CatVideoFest 2021 | $4,326 | - | - | - | - | 8 | 2 | Oscilloscope | - | false |
| 39 | Never Gonna Snow Again | $4,270 | $2,828 | 66.2% | $1,442 | 33.8% | 5 | 1 | Kino Lorber | - | false |
| 40 | Sabaya | $3,658 | - | - | - | - | 1 | 1 | MTV Documentary Films | - | false |
| 41 | Mandibles | $3,557 | $2,500 | 70.3% | $1,057 | 29.7% | 14 | 2 | Magnet Releasing | - | false |
| 42 | No Ordinary Man | $3,519 | - | - | - | - | 9 | 3 | Oscilloscope | - | false |
| 43 | Mama Weed | $3,474 | $2,270 | 65.3% | $1,204 | 34.7% | 8 | 3 | Music Box Films | - | false |
| 44 | Werewolves Within | $3,371 | $1,779 | 52.8% | $1,592 | 47.2% | 11 | 6 | IFC Films | - | false |
| 45 | Casanova, Last Love | $3,124 | $2,051 | 65.6% | $1,073 | 34.4% | 6 | 4 | Cohen Media Group | - | false |
| 46 | Summertime | $2,960 | - | - | - | - | 10 | 4 | Good Deed Entertainment | - | false |
| 47 | Lydia Lunch: The War Is Never Over | $1,740 | - | - | - | - | 2 | 6 | Kino Lorber | - | false |
| 48 | Dream Horse | $1,335 | $878 | 65.8% | $457 | 34.2% | 17 | 11 | Bleecker Street Media | - | false |
| 49 | Can You Bring It: Bill T. Jones and D-Man in the Waters | $1,057 | $357 | 33.8% | $700 | 66.2% | 4 | 3 | Kino Lorber | - | false |
| 50 | The Dry | $667 | $453 | 67.9% | $214 | 32.1% | 2 | 11 | IFC Films | - | false |
| 51 | Secret Agent Dingledorf and His Trusty Dog Splat | $460 | $200 | 43.5% | $260 | 56.5% | 3 | 5 | Integrity Releasing | - | false |
| 52 | The Ladykillers 2021 Re-release | $433 | $265 | 61.2% | $168 | 38.8% | 1 | 9 | Rialto Pictures | - | false |
| 53 | The Red Circle 2021 Re-release | $412 | $121 | 29.4% | $291 | 70.6% | 1 | 6 | Rialto Pictures | - | false |
| 54 | The Perfect Candidate | $207 | $60 | 29% | $147 | 71% | 1 | 12 | Music Box Films | - | false |
| 55 | Summer of 85 | $148 | $93 | 62.8% | $55 | 37.2% | 2 | 7 | Music Box Films | - | false |
| 56 | Shiva Baby | $32 | $32 | 100% | $0 | - | 1 | 18 | Utopia | - | false |
