| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Old | $23,853,255 | $16,854,735 | 70.7% | $6,998,520 | 29.3% | 3,355 | 1 | Universal Pictures | - | false |
| 2 | Snake Eyes | $18,282,544 | $13,367,853 | 73.1% | $4,914,691 | 26.9% | 3,521 | 1 | Paramount Pictures | - | false |
| 3 | Black Widow | $17,434,179 | $11,618,898 | 66.6% | $5,815,281 | 33.4% | 4,250 | 3 | Walt Disney Studios Motion Pictures | - | false |
| 4 | Space Jam: A New Legacy | $14,666,838 | $9,580,220 | 65.3% | $5,086,618 | 34.7% | 4,002 | 2 | Warner Bros. | - | false |
| 5 | F9: The Fast Saga | $7,197,790 | $4,820,075 | 67% | $2,377,715 | 33% | 2,850 | 5 | Universal Pictures | - | false |
| 6 | Escape Room: Tournament of Champions | $5,703,462 | $3,516,543 | 61.7% | $2,186,919 | 38.3% | 2,815 | 2 | Sony Pictures Releasing | - | false |
| 7 | The Boss Baby 2: Family Business | $4,734,605 | $2,858,880 | 60.4% | $1,875,725 | 39.6% | 2,773 | 4 | Universal Pictures | - | false |
| 8 | The Forever Purge | $3,572,605 | $2,379,775 | 66.6% | $1,192,830 | 33.4% | 2,113 | 4 | Universal Pictures | - | false |
| 9 | A Quiet Place Part II | $1,896,907 | $1,205,122 | 63.5% | $691,785 | 36.5% | 1,397 | 9 | Paramount Pictures | - | false |
| 10 | Roadrunner: A Film About Anthony Bourdain | $1,358,675 | $879,630 | 64.7% | $479,045 | 35.3% | 954 | 2 | Focus Features | - | false |
| 11 | Joe Bell | $1,095,444 | $749,635 | 68.4% | $345,809 | 31.6% | 1,094 | 1 | Roadside Attractions | - | false |
| 12 | Pig | $945,280 | $587,853 | 62.2% | $357,427 | 37.8% | 588 | 2 | Neon | - | false |
| 13 | Cruella | $811,542 | $500,584 | 61.7% | $310,958 | 38.3% | 495 | 9 | Walt Disney Studios Motion Pictures | - | false |
| 14 | Hitman's Wife's Bodyguard | $485,897 | $316,620 | 65.2% | $169,277 | 34.8% | 476 | 7 | Lionsgate | - | false |
| 15 | Peter Rabbit 2: The Runaway | $454,949 | $265,465 | 58.4% | $189,484 | 41.6% | 578 | 7 | Sony Pictures Releasing | - | false |
| 16 | In the Heights | $315,704 | $194,223 | 61.5% | $121,481 | 38.5% | 305 | 7 | Warner Bros. | - | false |
| 17 | The Conjuring: The Devil Made Me Do It | $276,272 | - | - | - | - | 1,716 | 8 | Warner Bros. | - | false |
| 18 | Weathering with You | $257,893 | $93,984 | 36.4% | $163,909 | 63.6% | 644 | 81 | GKIDS | - | false |
| 19 | Zola | $194,445 | $119,584 | 61.5% | $74,861 | 38.5% | 229 | 5 | A24 | - | false |
| 20 | Kaamelott: First Installment | $188,000 | $188,000 | 100% | $0 | - | 26 | 1 | Paramount Pictures | - | false |
| 21 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $167,180 | $104,392 | 62.4% | $62,788 | 37.6% | 150 | 5 | Searchlight Pictures | - | false |
| 22 | 12 Mighty Orphans | $85,368 | $59,940 | 70.2% | $25,428 | 29.8% | 74 | 7 | Sony Pictures Releasing | - | false |
| 23 | Once I Was Engaged | $78,474 | $35,304 | 45% | $43,170 | 55% | 32 | 2 | Excel Entertainment | - | false |
| 24 | Spirit Untamed | $68,705 | $39,615 | 57.7% | $29,090 | 42.3% | 895 | 8 | Universal Pictures | - | false |
| 25 | CatVideoFest 2021 | $50,467 | $39,519 | 78.3% | $10,948 | 21.7% | 40 | 1 | Oscilloscope | - | false |
| 26 | Queen Bees | $46,335 | $27,470 | 59.3% | $18,865 | 40.7% | 83 | 7 | Gravitas Ventures | - | false |
| 27 | Raya and the Last Dragon | $35,481 | $29,571 | 83.3% | $5,910 | 16.7% | 35 | 21 | Walt Disney Studios Motion Pictures | - | false |
| 28 | Witnesses | $22,050 | $10,915 | 49.5% | $11,135 | 50.5% | 17 | 8 | Purdie Distribution | - | false |
| 29 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $21,595 | $12,166 | 56.3% | $9,429 | 43.7% | 24 | 14 | FUNimation Entertainment | - | false |
| 30 | Ailey | $21,545 | $15,091 | 70% | $6,454 | 30% | 2 | 1 | Neon | - | false |
| 31 | Settlers | $15,825 | $13,045 | 82.4% | $2,780 | 17.6% | 30 | 1 | IFC Films | - | false |
| 32 | Mandibles | $13,779 | $7,346 | 53.3% | $6,433 | 46.7% | 24 | 1 | Magnet Releasing | - | false |
| 33 | Secret Agent Dingledorf and His Trusty Dog Splat | $13,300 | $8,865 | 66.6% | $4,435 | 33.4% | 30 | 4 | Integrity Releasing | - | false |
| 34 | How It Ends | $10,036 | $5,792 | 57.7% | $4,244 | 42.3% | 10 | 2 | United Artists | - | false |
| 35 | I Carry You with Me | $9,689 | $8,332 | 86% | $1,357 | 14% | 44 | 5 | Sony Pictures Classics | - | false |
| 36 | Without Getting Killed or Caught | $9,463 | $6,350 | - | - | - | 1 | 1 | mTuckman Media | - | true |
| 37 | The Truffle Hunters | $8,676 | $5,503 | 63.4% | $3,173 | 36.6% | 12 | 21 | Sony Pictures Classics | - | false |
| 38 | Wrath of Man | $8,188 | $5,536 | 67.6% | $2,652 | 32.4% | 37 | 12 | United Artists Releasing | - | false |
| 39 | Werewolves Within | $8,025 | $5,397 | 67.2% | $2,628 | 32.8% | 17 | 5 | IFC Films | - | false |
| 40 | The Swimming Pool 2021 Re-release | $7,864 | $4,947 | 62.9% | $2,917 | 37.1% | 3 | 11 | Rialto Distribution | - | false |
| 41 | The Loneliest Whale: The Search for 52 | $7,239 | $4,626 | 63.9% | $2,613 | 36.1% | 20 | 3 | Bleecker Street Media | - | false |
| 42 | The Red Circle 2021 Re-release | $7,018 | $4,146 | 59.1% | $2,872 | 40.9% | 4 | 5 | Rialto Pictures | - | false |
| 43 | Summertime | $6,760 | - | - | - | - | 29 | 3 | Good Deed Entertainment | - | false |
| 44 | Dream Horse | $6,010 | $3,930 | 65.4% | $2,080 | 34.6% | 17 | 10 | Bleecker Street Media | - | false |
| 45 | Here After | $5,612 | $5,612 | 100% | $0 | - | 1 | 1 | Vertical Entertainment | - | false |
| 46 | Mama Weed | $4,666 | $3,104 | 66.5% | $1,562 | 33.5% | 10 | 2 | Music Box Films | - | false |
| 47 | No Ordinary Man | $4,013 | $2,513 | 62.6% | $1,500 | 37.4% | 9 | 2 | Oscilloscope | - | false |
| 48 | Rita Moreno: Just a Girl Who Decided to Go for It | $3,943 | $2,466 | 62.5% | $1,477 | 37.5% | 12 | 6 | Roadside Attractions | - | false |
| 49 | Can You Bring It: Bill T. Jones and D-Man in the Waters | $3,712 | $2,752 | 74.1% | $960 | 25.9% | 7 | 2 | Kino Lorber | - | false |
| 50 | The Ladykillers 2021 Re-release | $2,564 | $1,404 | 54.8% | $1,160 | 45.2% | 3 | 8 | Rialto Pictures | - | false |
| 51 | Victim of Love | $2,393 | $1,958 | 81.8% | $435 | 18.2% | 1 | 1 | Indican Pictures | - | false |
| 52 | Casanova, Last Love | $2,132 | $1,627 | 76.3% | $505 | 23.7% | 4 | 3 | Cohen Media Group | - | false |
| 53 | Summer of 85 | $1,900 | $1,206 | 63.5% | $694 | 36.5% | 5 | 6 | Music Box Films | - | false |
| 54 | Together Together | $1,602 | $138 | 8.6% | $1,464 | 91.4% | 2 | 14 | Bleecker Street Media | - | false |
| 55 | Rock Paper Scissors | $1,471 | $969 | 65.9% | $502 | 34.1% | 1 | 2 | Indican Pictures | - | false |
| 56 | Truman & Tennessee: An Intimate Conversation | $1,093 | $425 | 38.9% | $668 | 61.1% | 4 | 6 | Kino Lorber | - | false |
| 57 | The Dry | $1,019 | $412 | 40.4% | $607 | 59.6% | 3 | 10 | IFC Films | - | false |
| 58 | Undine | $481 | $198 | 41.2% | $283 | 58.8% | 2 | 8 | IFC Films | - | false |
| 59 | Shiva Baby | $150 | $32 | 21.3% | $118 | 78.7% | 1 | 17 | Utopia | - | false |
| 60 | Mission Stories | $146 | $96 | 65.8% | $50 | 34.2% | 1 | 12 | Excel Entertainment | - | false |
| 61 | The Perfect Candidate | $56 | $56 | 100% | $0 | - | 1 | 11 | Music Box Films | - | false |
| - | This Is My Desire | - | - | - | - | - | 1 | 1 | Janus Films | - | false |
