| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Black Widow | $105,761,671 | $80,366,312 | 76% | $25,395,359 | 24% | 4,160 | 1 | Walt Disney Studios Motion Pictures | - | false |
| 2 | F9: The Fast Saga | $16,773,230 | $11,436,785 | 68.2% | $5,336,445 | 31.8% | 3,649 | 3 | Universal Pictures | - | false |
| 3 | The Boss Baby 2: Family Business | $13,875,165 | $8,876,235 | 64% | $4,998,930 | 36% | 3,688 | 2 | Universal Pictures | - | false |
| 4 | The Forever Purge | $11,015,795 | $7,144,485 | 64.9% | $3,871,310 | 35.1% | 3,058 | 2 | Universal Pictures | - | false |
| 5 | A Quiet Place Part II | $5,033,575 | $3,155,430 | 62.7% | $1,878,145 | 37.3% | 2,359 | 7 | Paramount Pictures | - | false |
| 6 | Cruella | $3,750,852 | $2,370,111 | 63.2% | $1,380,741 | 36.8% | 1,875 | 7 | Walt Disney Studios Motion Pictures | - | false |
| 7 | Hitman's Wife's Bodyguard | $2,488,284 | $1,630,927 | 65.5% | $857,357 | 34.5% | 1,904 | 5 | Lionsgate | - | false |
| 8 | Peter Rabbit 2: The Runaway | $2,242,315 | $1,262,805 | 56.3% | $979,510 | 43.7% | 1,958 | 5 | Sony Pictures Releasing | - | false |
| 9 | Zola | $1,094,075 | $636,564 | 58.2% | $457,511 | 41.8% | 1,401 | 3 | A24 | - | false |
| 10 | The Conjuring: The Devil Made Me Do It | $1,046,787 | $655,324 | 62.6% | $391,463 | 37.4% | 1,716 | 6 | Warner Bros. | - | false |
| 11 | In the Heights | $1,030,966 | $612,520 | 59.4% | $418,446 | 40.6% | 1,405 | 5 | Warner Bros. | - | false |
| 12 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $638,842 | $377,634 | 59.1% | $261,208 | 40.9% | 752 | 3 | Searchlight Pictures | - | false |
| 13 | Spirit Untamed | $224,515 | $140,020 | 62.4% | $84,495 | 37.6% | 968 | 6 | Universal Pictures | - | false |
| 14 | 12 Mighty Orphans | $213,159 | $136,569 | 64.1% | $76,590 | 35.9% | 185 | 5 | Sony Pictures Releasing | - | false |
| 15 | Queen Bees | $123,735 | $73,500 | 59.4% | $50,235 | 40.6% | 163 | 5 | Gravitas Ventures | - | false |
| 16 | The House Next Door: Meet the Blacks 2 | $64,913 | $41,997 | 64.7% | $22,916 | 35.3% | 44 | 5 | Hidden Empire Film Group (HEFG) | - | false |
| 17 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $64,338 | $34,980 | 54.4% | $29,358 | 45.6% | 42 | 12 | FUNimation Entertainment | - | false |
| 18 | The Loneliest Whale: The Search for 52 | $64,298 | $41,131 | 64% | $23,167 | 36% | 71 | 1 | Bleecker Street Media | - | false |
| 19 | I Carry You with Me | $47,011 | $30,857 | 65.6% | $16,154 | 34.4% | 57 | 3 | Sony Pictures Classics | - | false |
| 20 | Raya and the Last Dragon | $45,681 | $33,591 | 73.5% | $12,090 | 26.5% | 55 | 19 | Walt Disney Studios Motion Pictures | - | false |
| 21 | Werewolves Within | $43,615 | $25,023 | 57.4% | $18,592 | 42.6% | 63 | 3 | IFC Films | - | false |
| 22 | Witnesses | $43,431 | $20,118 | 46.3% | $23,313 | 53.7% | 28 | 6 | Purdie Distribution | - | false |
| 23 | Dream Horse | $26,242 | $15,800 | 60.2% | $10,442 | 39.8% | 44 | 8 | Bleecker Street Media | - | false |
| 24 | Wrath of Man | $19,650 | $12,435 | 63.3% | $7,215 | 36.7% | 50 | 10 | United Artists Releasing | - | false |
| 25 | The Truffle Hunters | $18,529 | $11,496 | 62% | $7,033 | 38% | 18 | 19 | Sony Pictures Classics | - | false |
| 26 | The Red Circle 2021 Re-release | $11,771 | $5,942 | 50.5% | $5,829 | 49.5% | 4 | 3 | Rialto Pictures | - | false |
| 27 | Rita Moreno: Just a Girl Who Decided to Go for It | $9,591 | $5,838 | 60.9% | $3,753 | 39.1% | 23 | 4 | Roadside Attractions | - | false |
| 28 | Summer of 85 | $8,503 | $5,108 | 60.1% | $3,395 | 39.9% | 13 | 4 | Music Box Films | - | false |
| 29 | The God Committee | $8,471 | $4,838 | 57.1% | $3,633 | 42.9% | 25 | 2 | Vertical Entertainment | - | false |
| 30 | Truman & Tennessee: An Intimate Conversation | $7,004 | - | - | - | - | 13 | 4 | Kino Lorber | - | false |
| 31 | The Swimming Pool 2021 Re-release | $6,928 | $3,813 | 55% | $3,115 | 45% | 8 | 9 | Rialto Distribution | - | false |
| 32 | Scales | $4,617 | $3,090 | 66.9% | $1,527 | 33.1% | 2 | 1 | Variance Films | - | false |
| 33 | First Date | $3,026 | $2,108 | 69.7% | $918 | 30.3% | 13 | 2 | Magnolia Pictures | - | false |
| 34 | Shiva Baby | $2,700 | $2,158 | 79.9% | $542 | 20.1% | 5 | 15 | Utopia | - | false |
| 35 | Censor | $2,610 | $1,054 | 40.4% | $1,556 | 59.6% | 6 | 5 | Magnolia Pictures | - | false |
| 36 | The Ladykillers 2021 Re-release | $1,585 | $1,094 | 69% | $491 | 31% | 3 | 6 | Rialto Pictures | - | false |
| 37 | Lydia Lunch: The War Is Never Over | $1,329 | - | - | - | - | 4 | 3 | Kino Lorber | - | false |
| 38 | Casanova, Last Love | $964 | - | - | - | - | 4 | 1 | Cohen Media Group | - | false |
| 39 | A Soldier's Story 2: Return from the Dead | $436 | $1,724 | 395.4% | $-1,288 | - | 2 | 3 | Indican Pictures | - | false |
| 40 | About Endlessness | $202 | $202 | 100% | $0 | - | 1 | 11 | Magnolia Pictures | - | false |
| 41 | The Perfect Candidate | $114 | $114 | 100% | $0 | - | 1 | 9 | Music Box Films | - | false |
