| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | F9: The Fast Saga | $37,341,765 | $23,008,860 | 61.6% | $14,332,905 | 38.4% | 4,203 | 2 | Universal Pictures | - | false |
| 2 | The Boss Baby 2: Family Business | $26,046,510 | $16,000,665 | 61.4% | $10,045,845 | 38.6% | 3,644 | 1 | Universal Pictures | - | false |
| 3 | The Forever Purge | $20,734,915 | $12,551,220 | 60.5% | $8,183,695 | 39.5% | 3,051 | 1 | Universal Pictures | - | false |
| 4 | A Quiet Place Part II | $7,482,636 | $4,101,048 | 54.8% | $3,381,588 | 45.2% | 2,826 | 6 | Paramount Pictures | - | false |
| 5 | Hitman's Wife's Bodyguard | $5,031,680 | $3,002,155 | 59.7% | $2,029,525 | 40.3% | 3,361 | 4 | Lionsgate | - | false |
| 6 | Cruella | $4,527,681 | $2,386,652 | 52.7% | $2,141,029 | 47.3% | 2,380 | 6 | Walt Disney Studios Motion Pictures | - | false |
| 7 | Peter Rabbit 2: The Runaway | $4,283,522 | $2,189,910 | 51.1% | $2,093,612 | 48.9% | 2,954 | 4 | Sony Pictures Releasing | - | false |
| 8 | The Conjuring: The Devil Made Me Do It | $2,242,090 | $1,260,000 | - | - | - | 1,716 | 5 | Warner Bros. | - | true |
| 9 | Zola | $2,114,311 | $1,200,013 | 56.8% | $914,298 | 43.2% | 1,468 | 2 | A24 | - | false |
| 10 | In the Heights | $2,075,528 | $1,185,000 | - | - | - | 1,405 | 4 | Warner Bros. | - | true |
| 11 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $1,052,524 | $647,634 | 61.5% | $404,890 | 38.5% | 752 | 2 | Searchlight Pictures | - | false |
| 12 | Spirit Untamed | $648,210 | $353,690 | 54.6% | $294,520 | 45.4% | 1,296 | 5 | Universal Pictures | - | false |
| 13 | 12 Mighty Orphans | $439,649 | $204,709 | 46.6% | $234,940 | 53.4% | 338 | 4 | Sony Pictures Releasing | - | false |
| 14 | Nobody | $349,250 | $278,310 | 79.7% | $70,940 | 20.3% | 224 | 15 | Universal Pictures | - | false |
| 15 | Queen Bees | $164,007 | $81,919 | 50% | $82,088 | 50% | 170 | 4 | Gravitas Ventures | - | false |
| 16 | Werewolves Within | $140,917 | $86,100 | 61.1% | $54,817 | 38.9% | 209 | 2 | IFC Films | - | false |
| 17 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $123,039 | $58,568 | 47.6% | $64,471 | 52.4% | 81 | 11 | FUNimation Entertainment | - | false |
| 18 | Wrath of Man | $78,025 | $56,158 | 72% | $21,867 | 28% | 82 | 9 | United Artists Releasing | - | false |
| 19 | Witnesses | $75,923 | $30,290 | 39.9% | $45,633 | 60.1% | 36 | 5 | Purdie Distribution | - | false |
| 20 | Raya and the Last Dragon | $63,156 | $42,510 | 67.3% | $20,646 | 32.7% | 75 | 18 | Walt Disney Studios Motion Pictures | - | false |
| 21 | The Sparks Brothers | $46,745 | $24,950 | 53.4% | $21,795 | 46.6% | 130 | 3 | Focus Features | - | false |
| 22 | Spiral | $39,585 | $23,725 | 59.9% | $15,860 | 40.1% | 102 | 8 | Lionsgate | - | false |
| 23 | I Carry You with Me | $38,239 | $21,624 | 56.6% | $16,615 | 43.4% | 24 | 2 | Sony Pictures Classics | - | false |
| 24 | Dream Horse | $25,527 | $14,996 | 58.8% | $10,531 | 41.2% | 73 | 7 | Bleecker Street Media | - | false |
| 25 | Rita Moreno: Just a Girl Who Decided to Go for It | $25,498 | $15,644 | 61.4% | $9,854 | 38.6% | 56 | 3 | Roadside Attractions | - | false |
| 26 | The God Committee | $24,463 | $12,237 | 50% | $12,226 | 50% | 28 | 1 | Vertical Entertainment | - | false |
| 27 | The Truffle Hunters | $22,490 | $13,852 | 61.6% | $8,638 | 38.4% | 25 | 18 | Sony Pictures Classics | - | false |
| 28 | Lansky | $21,260 | $13,614 | 64% | $7,646 | 36% | 42 | 2 | Vertical Entertainment | - | false |
| 29 | Summer of 85 | $14,034 | $7,961 | 56.7% | $6,073 | 43.3% | 19 | 3 | Music Box Films | - | false |
| 30 | The Swimming Pool 2021 Re-release | $13,321 | $6,875 | 51.6% | $6,446 | 48.4% | 9 | 8 | Rialto Distribution | - | false |
| 31 | Truman & Tennessee: An Intimate Conversation | $13,055 | $8,872 | 68% | $4,183 | 32% | 21 | 3 | Kino Lorber | - | false |
| 32 | First Date | $12,948 | $8,882 | 68.6% | $4,066 | 31.4% | 21 | 1 | Magnolia Pictures | - | false |
| 33 | The Red Circle 2021 Re-release | $11,392 | $5,925 | 52% | $5,467 | 48% | 1 | 2 | Rialto Pictures | - | false |
| 34 | The Dry | $7,564 | $4,670 | 61.7% | $2,894 | 38.3% | 7 | 7 | IFC Films | - | false |
| 35 | Shiva Baby | $5,125 | - | - | - | - | 7 | 14 | Utopia | - | false |
| 36 | A Soldier's Story 2: Return from the Dead | $4,232 | - | - | - | - | 4 | 2 | Indican Pictures | - | false |
| 37 | The Ladykillers 2021 Re-release | $4,145 | $2,524 | 60.9% | $1,621 | 39.1% | 3 | 5 | Rialto Pictures | - | false |
| 38 | Undine | $3,829 | $1,981 | 51.7% | $1,848 | 48.3% | 6 | 5 | IFC Films | - | false |
| 39 | Lydia Lunch: The War Is Never Over | $3,486 | $1,710 | 49% | $1,776 | 51% | 1 | 2 | Kino Lorber | - | false |
| 40 | Censor | $2,943 | $1,976 | 67.1% | $967 | 32.9% | 4 | 4 | Magnolia Pictures | - | false |
| 41 | Our Ladies | $2,552 | $1,112 | 43.6% | $1,440 | 56.4% | 12 | 3 | Sony Pictures Releasing | - | false |
| 42 | About Endlessness | $2,222 | $1,419 | 63.9% | $803 | 36.1% | 1 | 10 | Magnolia Pictures | - | false |
| 43 | Operation Portugal | $1,096 | $733 | 66.9% | $363 | 33.1% | 10 | 1 | Sony Pictures Releasing | - | false |
| 44 | Together Together | $666 | $476 | 71.5% | $190 | 28.5% | 4 | 11 | Bleecker Street Media | - | false |
| 45 | Holler | $650 | $253 | 38.9% | $397 | 61.1% | 4 | 4 | IFC Films | - | false |
| 46 | The Evil Next Door | $466 | $128 | 27.5% | $338 | 72.5% | 2 | 2 | Magnolia Pictures | - | false |
| 47 | Sweat | $303 | - | - | - | - | 2 | 3 | MUBI | - | false |
