| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | The Twilight Saga: Eclipse | $92,744,978 | - | - | - | - | 4,416 | 1 | Summit Entertainment | - | false |
| 2 | Toy Story 3 | $91,274,487 | $59,337,669 | 65% | $31,936,818 | 35% | 4,028 | 2 | Walt Disney Studios Motion Pictures | - | false |
| 3 | Grown Ups | $58,581,515 | $40,506,562 | 69.2% | $18,074,953 | 30.8% | 3,534 | 1 | Sony Pictures Releasing | - | false |
| 4 | Knight and Day 2010 Re-release | $28,020,086 | $20,139,985 | 71.9% | $7,880,101 | 28.1% | 3,098 | 2 | Twentieth Century Fox | - | false |
| 5 | The Karate Kid | $23,281,958 | $15,547,421 | 66.8% | $7,734,537 | 33.2% | 3,291 | 3 | Sony Pictures Releasing | - | false |
| 6 | The Last Airbender | $17,511,097 | - | - | - | - | 3,169 | 1 | Paramount Pictures | - | false |
| 7 | The A-Team | $9,247,972 | $6,204,454 | 67.1% | $3,043,518 | 32.9% | 2,162 | 3 | Twentieth Century Fox | - | false |
| 8 | Shrek Forever After | $4,950,751 | $3,101,365 | 62.6% | $1,849,386 | 37.4% | 2,340 | 6 | DreamWorks | - | false |
| 9 | Get Him to the Greek | $4,765,880 | $3,140,780 | 65.9% | $1,625,100 | 34.1% | 990 | 4 | Universal Pictures | - | false |
| 10 | Prince of Persia: The Sands of Time | $4,077,975 | $2,845,684 | 69.8% | $1,232,291 | 30.2% | 869 | 5 | Walt Disney Studios Motion Pictures | - | false |
| 11 | Killers | $2,695,256 | $1,938,681 | 71.9% | $756,575 | 28.1% | 838 | 4 | Lionsgate | - | false |
| 12 | Twilight/New Moon Double Bill | $2,385,237 | - | - | - | - | 2,037 | 1 | Summit Entertainment | - | false |
| 13 | Jonah Hex | $2,270,185 | $1,627,442 | 71.7% | $642,743 | 28.3% | 540 | 2 | Warner Bros. | - | false |
| 14 | Iron Man 2 | $2,147,194 | $1,436,378 | 66.9% | $710,816 | 33.1% | 1,169 | 8 | Paramount Pictures | - | false |
| 15 | Sex and the City 2 | $1,841,499 | $1,219,345 | 66.2% | $622,154 | 33.8% | 401 | 6 | Warner Bros. | - | false |
| 16 | Marmaduke | $1,424,486 | $977,386 | 68.6% | $447,100 | 31.4% | 385 | 4 | Twentieth Century Fox | - | false |
| 17 | Letters to Juliet | $991,424 | $406,548 | 41% | $584,876 | 59% | 509 | 7 | Summit Entertainment | - | false |
| 18 | Robin Hood | $932,230 | $648,925 | 69.6% | $283,305 | 30.4% | 372 | 7 | Universal Pictures | - | false |
| 19 | How to Train Your Dragon | $870,205 | $477,499 | 54.9% | $392,706 | 45.1% | 333 | 14 | DreamWorks | - | false |
| 20 | Solitary Man | $664,695 | $480,070 | 72.2% | $184,625 | 27.8% | 177 | 6 | Anchor Bay Films | - | false |
| 21 | Winter's Bone | $654,938 | $437,378 | 66.8% | $217,560 | 33.2% | 70 | 3 | Roadside Attractions | - | false |
| 22 | Joan Rivers: A Piece of Work | $557,758 | $362,553 | 65% | $195,205 | 35% | 86 | 3 | IFC Films | - | false |
| 23 | Hubble | $499,407 | $233,822 | 46.8% | $265,585 | 53.2% | 50 | 15 | Warner Bros. | - | false |
| 24 | Cyrus | $452,842 | $301,227 | 66.5% | $151,615 | 33.5% | 17 | 2 | Fox Searchlight Pictures | - | false |
| 25 | Please Give | $406,377 | $276,398 | 68% | $129,979 | 32% | 219 | 9 | Sony Pictures Classics | - | false |
| 26 | Splice 2010 Re-release | $382,469 | $240,365 | 62.8% | $142,104 | 37.2% | 155 | 4 | Warner Bros. | - | false |
| 27 | I Am Love | $376,605 | $248,120 | 65.9% | $128,485 | 34.1% | 27 | 2 | Magnolia Pictures | - | false |
| 28 | Date Night | $368,254 | $241,385 | 65.6% | $126,869 | 34.4% | 286 | 12 | Twentieth Century Fox | - | false |
| 29 | The Girl with the Dragon Tattoo | $358,802 | $222,990 | 62.2% | $135,812 | 37.8% | 139 | 15 | Music Box Films | - | false |
| 30 | The Secret in Their Eyes | $337,897 | $217,193 | 64.3% | $120,704 | 35.7% | 143 | 11 | Sony Pictures Classics | - | false |
| 31 | Clash of the Titans | $267,848 | $164,383 | 61.4% | $103,465 | 38.6% | 216 | 13 | Warner Bros. | - | false |
| 32 | Furry Vengeance | $207,552 | $123,352 | 59.4% | $84,200 | 40.6% | 157 | 9 | Summit Entertainment | - | false |
| 33 | City Island | $190,831 | $131,342 | 68.8% | $59,489 | 31.2% | 105 | 15 | Anchor Bay Films | - | false |
| 34 | The Back-up Plan | $188,161 | $124,579 | 66.2% | $63,582 | 33.8% | 147 | 10 | CBS Films | - | false |
| 35 | Mother and Child | $156,463 | $94,751 | 60.6% | $61,712 | 39.4% | 119 | 8 | Sony Pictures Classics | - | false |
| 36 | The Bounty Hunter | $148,881 | $99,460 | 66.8% | $49,421 | 33.2% | 104 | 15 | Sony Pictures Releasing | - | false |
| 37 | Death at a Funeral | $141,926 | $141,926 | 100% | $0 | - | 156 | 11 | Screen Gems | - | false |
| 38 | The Last Song | $136,837 | $85,334 | 62.4% | $51,503 | 37.6% | 123 | 14 | Walt Disney Studios Motion Pictures | - | false |
| 39 | Micmacs | $132,872 | $79,381 | 59.7% | $53,491 | 40.3% | 52 | 5 | Sony Pictures Classics | - | false |
| 40 | Oceans | $130,871 | $77,336 | 59.1% | $53,535 | 40.9% | 127 | 11 | Walt Disney Studios Motion Pictures | - | false |
| 41 | A Nightmare on Elm Street | $130,371 | $80,064 | 61.4% | $50,307 | 38.6% | 155 | 9 | Warner Bros. | - | false |
| 42 | Coco Chanel & Igor Stravinsky | $129,176 | $78,281 | 60.6% | $50,895 | 39.4% | 20 | 3 | Sony Pictures Classics | - | false |
| 43 | Exit Through the Gift Shop | $125,717 | $74,791 | 59.5% | $50,926 | 40.5% | 36 | 11 | Producers Distribution Agency (PDA) | - | false |
| 44 | Raavan | $116,970 | $89,972 | 76.9% | $26,998 | 23.1% | 115 | 2 | Reliance Big Pictures | - | false |
| 45 | Diary of a Wimpy Kid | $114,011 | $61,842 | 54.2% | $52,169 | 45.8% | 105 | 15 | Twentieth Century Fox | - | false |
| 46 | Just Wright | $111,562 | $74,184 | 66.5% | $37,378 | 33.5% | 111 | 7 | Fox Searchlight Pictures | - | false |
| 47 | Ondine | $100,896 | $63,606 | 63% | $37,290 | 37% | 39 | 4 | Magnolia Pictures | - | false |
| 48 | Harry Brown | $89,731 | $65,150 | 72.6% | $24,581 | 27.4% | 56 | 9 | The Samuel Goldwyn Company | - | false |
| 49 | Babies | $87,948 | $45,041 | 51.2% | $42,907 | 48.8% | 64 | 8 | Focus Features | - | false |
| 50 | I Hate Luv Storys | $86,771 | - | - | - | - | 85 | 1 | UTV Motion Pictures | - | false |
| 51 | Under the Sea 3D | $85,830 | $32,781 | 38.2% | $53,049 | 61.8% | 13 | 72 | Warner Bros. | - | false |
| 52 | Avatar | $77,156 | $44,572 | 57.8% | $32,584 | 42.2% | 15 | 28 | Twentieth Century Fox | - | false |
| 53 | Magnificent Desolation: Walking on the Moon | $68,509 | $25,090 | 36.6% | $43,419 | 63.4% | 2 | 249 | IMAX | - | false |
| 54 | Wild Grass | $66,678 | $39,162 | 58.7% | $27,516 | 41.3% | 5 | 1 | Sony Pictures Classics | - | false |
| 55 | Kick-Ass | $62,724 | $34,926 | 55.7% | $27,798 | 44.3% | 102 | 11 | Lionsgate | - | false |
| 56 | Restrepo | $60,623 | $35,581 | 58.7% | $25,042 | 41.3% | 2 | 1 | National Geographic Entertainment | - | false |
| 57 | Alice in Wonderland | $43,783 | $27,399 | 62.6% | $16,384 | 37.4% | 65 | 17 | Walt Disney Studios Motion Pictures | - | false |
| 58 | Raajneeti | $41,439 | $29,933 | 72.2% | $11,506 | 27.8% | 30 | 4 | UTV Motion Pictures | - | false |
| 59 | The Killer Inside Me | $32,295 | $19,248 | 59.6% | $13,047 | 40.4% | 4 | 2 | IFC Films | - | false |
| 60 | South of the Border | $29,938 | $21,545 | 72% | $8,393 | 28% | 1 | 1 | Cinema Libre Studio | - | false |
| 61 | The City of Your Final Destination | $29,031 | $20,151 | 69.4% | $8,880 | 30.6% | 16 | 11 | Screen Media Films | - | false |
| 62 | Mademoiselle Chambon | $28,940 | $19,486 | 67.3% | $9,454 | 32.7% | 9 | 5 | Lorber Films | - | false |
| 63 | Stonewall Uprising | $28,146 | $16,238 | 57.7% | $11,908 | 42.3% | 6 | 3 | First Run | - | false |
| 64 | The Square 2010 Re-release | $25,390 | $17,804 | 70.1% | $7,586 | 29.9% | 8 | 12 | Apparition | - | false |
| 65 | Mid-August Lunch | $25,233 | $14,785 | 58.6% | $10,448 | 41.4% | 13 | 16 | Zeitgeist Films | - | false |
| 66 | Let it Rain | $24,467 | $15,660 | 64% | $8,807 | 36% | 5 | 2 | IFC Films | - | false |
| 67 | 8: The Mormon Proposition | $22,983 | $14,093 | 61.3% | $8,890 | 38.7% | 12 | 2 | Red Flag Releasing (RFR) | - | false |
| 68 | Deep Sea | $22,445 | $11,501 | 51.2% | $10,944 | 48.8% | 2 | 226 | Warner Bros. | - | false |
| 69 | Holy Rollers | $18,503 | $12,956 | 70% | $5,547 | 30% | 13 | 6 | First Independent Pictures | - | false |
| 70 | Agora | $16,990 | $12,565 | 74% | $4,425 | 26% | 3 | 5 | Newmarket Films | - | false |
| 71 | The Secret of Kells | $16,632 | $9,438 | 56.8% | $7,194 | 43.2% | 15 | 17 | GKIDS | - | false |
| 72 | Percy Jackson & the Olympians: The Lightning Thief | $15,466 | $8,883 | 57.4% | $6,583 | 42.6% | 19 | 20 | Twentieth Century Fox | - | false |
| 73 | La Mission | $14,691 | $9,066 | 61.7% | $5,625 | 38.3% | 11 | 12 | Screen Media Films | - | false |
| 74 | Love Ranch | $14,423 | - | - | - | - | 11 | 1 | Entertainment One | - | false |
| 75 | The Lottery | $13,696 | $10,064 | 73.5% | $3,632 | 26.5% | 3 | 3 | Variance Films | - | false |
| 76 | Breathless 2010 Re-release | $13,561 | $7,935 | 58.5% | $5,626 | 41.5% | 3 | 5 | Rialto Pictures | - | false |
| 77 | Dogtooth | $12,712 | $6,686 | 52.6% | $6,026 | 47.4% | 2 | 1 | Kino International | - | false |
| 78 | Kings of the Evening | $12,504 | $8,936 | 71.5% | $3,568 | 28.5% | 4 | 3 | Indican Pictures | - | false |
| 79 | Princess Kaiulani | $10,558 | $6,253 | 59.2% | $4,305 | 40.8% | 10 | 7 | Roadside Attractions | - | false |
| 80 | Only the Brave | $9,170 | $6,232 | 68% | $2,938 | 32% | 2 | 5 | Indican Pictures | - | false |
| 81 | Sea Monsters: A Prehistoric Adventure | $6,945 | $4,395 | 63.3% | $2,550 | 36.7% | 5 | 143 | National Geographic Entertainment | - | false |
| 82 | Ajami | $6,720 | $5,179 | 77.1% | $1,541 | 22.9% | 5 | 22 | Kino International | - | false |
| 83 | OSS 117: Lost in Rio | $6,585 | $4,595 | 69.8% | $1,990 | 30.2% | 3 | 8 | Music Box Films | - | false |
| 84 | A Prophet | $6,285 | $3,202 | 51% | $3,083 | 49% | 2 | 18 | Sony Pictures Classics | - | false |
| 85 | Survival of the Dead | $5,686 | $3,988 | 70.1% | $1,698 | 29.9% | 10 | 5 | Magnolia Pictures | - | false |
| 86 | The Joneses | $5,596 | $3,799 | 67.9% | $1,797 | 32.1% | 3 | 11 | Roadside Attractions | - | false |
| 87 | The Sun Behind the Clouds: Tibet's Struggle for Freedom | $5,284 | $2,619 | 49.6% | $2,665 | 50.4% | 4 | 14 | Balcony Releasing | - | false |
| 88 | The Cremaster Cycle 2010 Re-release | $5,122 | $2,335 | 45.6% | $2,787 | 54.4% | 1 | 12 | International Film Circuit | - | false |
| 89 | John Rabe | $4,609 | $2,998 | 65% | $1,611 | 35% | 3 | 6 | Strand Releasing | - | false |
| 90 | Father of My Children | $3,723 | $3,723 | 100% | $0 | - | 3 | 6 | IFC Films | - | false |
| 91 | Sweetgrass | $3,577 | $2,800 | 78.3% | $777 | 21.7% | 1 | 26 | The Cinema Guild | - | false |
| 92 | The Oath | $3,383 | $2,154 | 63.7% | $1,229 | 36.3% | 2 | 8 | Zeitgeist Films | - | false |
| 93 | Best Worst Movie | $3,291 | $2,610 | 79.3% | $681 | 20.7% | 1 | 10 | Abramorama | - | false |
| 94 | Chloe | $3,218 | $1,631 | 50.7% | $1,587 | 49.3% | 3 | 14 | Sony Pictures Classics | - | false |
| 95 | Racing Dreams | $3,007 | $1,190 | 39.6% | $1,817 | 60.4% | 3 | 6 | Hannover House | - | false |
| 96 | Cropsey | $2,937 | $1,680 | 57.2% | $1,257 | 42.8% | 2 | 4 | Cinema Purgatorio | - | false |
| 97 | Looking for Eric | $2,935 | $2,935 | 100% | $0 | - | 9 | 7 | IFC Films | - | false |
| 98 | The Good the Bad the Weird | $2,857 | $2,857 | 100% | $0 | - | 8 | 10 | IFC Films | - | false |
| 99 | Rosencrantz and Guildenstern Are Undead | $2,810 | $1,132 | 40.3% | $1,678 | 59.7% | 1 | 4 | Indican Pictures | - | false |
| 100 | Metropolis 2010 Re-release | $2,707 | $2,899 | 107.1% | $-192 | - | 1 | 8 | Kino International | - | false |
| 101 | Casino Jack and the United States of Money | $2,466 | $1,888 | 76.6% | $578 | 23.4% | 4 | 8 | Magnolia Pictures | - | false |
| 102 | The Human Centipede (First Sequence) | $2,307 | $2,307 | 100% | $0 | - | 7 | 9 | IFC Films | - | false |
| 103 | When You're Strange | $2,292 | - | - | - | - | 1 | 12 | Abramorama | - | false |
| 104 | Here and There | $2,247 | $2,028 | 90.2% | $219 | 9.8% | 2 | 7 | Cinema Purgatorio | - | false |
| 105 | Space Station 3D | $1,743 | $934 | 53.6% | $809 | 46.4% | 2 | 428 | IMAX | - | false |
| 106 | Dancing Across Borders | $1,106 | - | - | - | - | 1 | 14 | First Run | - | false |
| 107 | Touching Home | $885 | $648 | 73.2% | $237 | 26.8% | 2 | 9 | CFI Releasing | - | false |
| 108 | House | $797 | $797 | 100% | $0 | - | 1 | 24 | Janus Films | - | false |
| 109 | Breath Made Visible: Anna Halprin | $787 | $446 | 56.7% | $341 | 43.3% | 1 | 13 | Argot Pictures | - | false |
| 110 | Le Amiche | $752 | - | - | - | - | 1 | 2 | The Film Desk | - | false |
| 111 | Everyone Else | $723 | $535 | 74% | $188 | 26% | 1 | 12 | The Cinema Guild | - | false |
| 112 | Whiz Kids | $670 | $300 | 44.8% | $370 | 55.2% | 2 | 4 | Shadow Distribution | - | false |
| 113 | American Grindhouse | $666 | - | - | - | - | 1 | 2 | Lorber Films | - | false |
| 114 | Letters to God | $461 | $461 | 100% | $0 | - | 2 | 12 | Vivendi Entertainment | - | false |
| 115 | Dream Boy | $388 | $173 | 44.6% | $215 | 55.4% | 1 | 14 | Regent Releasing | - | false |
| - | U2 3D | - | - | - | - | - | - | 128 | National Geographic Entertainment | - | false |
| - | Off and Running | - | - | - | - | - | - | 22 | First Run | - | false |
| - | 2012: Time for Change | - | - | - | - | - | - | 12 | Mangusta Productions | - | false |
| - | Monsieur Verdoux | - | - | - | - | - | - | 120 | The Film Desk | - | false |
| - | The Nature of Existence | - | - | - | - | - | - | 2 | Walking Shadows | - | false |
| - | A Town Called Panic | - | - | - | - | - | - | 29 | Zeitgeist Films | - | false |
| - | Ran 2010 Re-release | - | - | - | - | - | - | 21 | Rialto Pictures | - | false |
| - | Behind the Burly Q | - | - | - | - | - | - | 10 | First Run | - | false |
| - | Small Change | - | - | - | - | - | - | 32 | The Film Desk | - | false |
