| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Alice in Wonderland | $146,625,356 | $116,101,023 | 79.2% | $30,524,333 | 20.8% | 3,728 | 1 | Walt Disney Studios Motion Pictures | - | false |
| 2 | Shutter Island | $17,342,918 | $13,225,411 | 76.3% | $4,117,507 | 23.7% | 3,178 | 3 | Paramount Pictures | - | false |
| 3 | Brooklyn's Finest | $17,061,472 | $13,350,299 | 78.2% | $3,711,173 | 21.8% | 1,936 | 1 | Overture Films | - | false |
| 4 | Cop Out | $11,997,367 | $9,289,311 | 77.4% | $2,708,056 | 22.6% | 3,150 | 2 | Warner Bros. | - | false |
| 5 | Avatar | $11,254,680 | $8,118,102 | 72.1% | $3,136,578 | 27.9% | 2,163 | 12 | Twentieth Century Fox | - | false |
| 6 | The Crazies | $9,315,055 | $7,078,851 | 76% | $2,236,204 | 24% | 2,479 | 2 | Overture Films | - | false |
| 7 | Percy Jackson & the Olympians: The Lightning Thief | $6,259,874 | $5,124,623 | 81.9% | $1,135,251 | 18.1% | 2,994 | 4 | Twentieth Century Fox | - | false |
| 8 | Valentine's Day | $5,293,827 | $4,154,110 | 78.5% | $1,139,717 | 21.5% | 3,040 | 4 | Warner Bros. | - | false |
| 9 | Crazy Heart | $4,858,694 | $3,312,591 | 68.2% | $1,546,103 | 31.8% | 1,274 | 13 | Fox Searchlight Pictures | - | false |
| 10 | Dear John | $3,689,052 | $2,782,079 | 75.4% | $906,973 | 24.6% | 2,496 | 5 | Screen Gems | - | false |
| 11 | The Wolfman | $2,238,885 | $1,636,835 | 73.1% | $602,050 | 26.9% | 1,829 | 4 | Universal Pictures | - | false |
| 12 | Tooth Fairy | $2,005,148 | $1,684,408 | 84% | $320,740 | 16% | 1,734 | 7 | Twentieth Century Fox | - | false |
| 13 | The Blind Side | $1,922,310 | $1,257,186 | 65.4% | $665,124 | 34.6% | 822 | 16 | Warner Bros. | - | false |
| 14 | The Ghost Writer | $1,726,134 | $1,287,646 | 74.6% | $438,488 | 25.4% | 147 | 3 | Summit Entertainment | - | false |
| 15 | The Last Station | $1,039,616 | $717,675 | 69% | $321,941 | 31% | 354 | 8 | Sony Pictures Classics | - | false |
| 16 | Up in the Air | $796,292 | $607,465 | 76.3% | $188,827 | 23.7% | 403 | 14 | Paramount Pictures | - | false |
| 17 | When in Rome | $744,078 | $575,254 | 77.3% | $168,824 | 22.7% | 504 | 6 | Walt Disney Studios Motion Pictures | - | false |
| 18 | The Book of Eli | $721,350 | $533,156 | 73.9% | $188,194 | 26.1% | 555 | 8 | Warner Bros. | - | false |
| 19 | Alvin and the Chipmunks: The Squeakquel | $678,851 | $544,451 | 80.2% | $134,400 | 19.8% | 562 | 12 | Twentieth Century Fox | - | false |
| 20 | The Hurt Locker | $611,000 | $439,000 | - | - | - | 274 | 37 | Summit Entertainment | - | true |
| 21 | Sherlock Holmes | $546,727 | $406,338 | 74.3% | $140,389 | 25.7% | 345 | 11 | Warner Bros. | - | false |
| 22 | A Single Man | $524,910 | $376,387 | 71.7% | $148,523 | 28.3% | 354 | 13 | The Weinstein Company | - | false |
| 23 | An Education | $490,731 | $365,603 | 74.5% | $125,128 | 25.5% | 223 | 22 | Sony Pictures Classics | - | false |
| 24 | It's Complicated | $463,725 | $317,670 | 68.5% | $146,055 | 31.5% | 321 | 11 | Universal Pictures | - | false |
| 25 | Edge of Darkness | $410,780 | $289,242 | 70.4% | $121,538 | 29.6% | 483 | 6 | Warner Bros. | - | false |
| 26 | The Princess and the Frog | $405,773 | $307,107 | 75.7% | $98,666 | 24.3% | 360 | 16 | Walt Disney Studios Motion Pictures | - | false |
| 27 | From Paris with Love | $365,368 | $267,682 | 73.3% | $97,686 | 26.7% | 401 | 5 | Lionsgate | - | false |
| 28 | A Prophet | $315,142 | $222,524 | 70.6% | $92,618 | 29.4% | 30 | 2 | Sony Pictures Classics | - | false |
| 29 | Old Dogs | $279,772 | $216,334 | 77.3% | $63,438 | 22.7% | 172 | 16 | Walt Disney Studios Motion Pictures | - | false |
| 30 | Precious | $257,470 | $181,674 | 70.6% | $75,796 | 29.4% | 217 | 18 | Lionsgate | - | false |
| 31 | The Twilight Saga: New Moon | $254,566 | $188,045 | 73.9% | $66,521 | 26.1% | 261 | 16 | Summit Entertainment | - | false |
| 32 | Legion | $251,996 | $176,689 | 70.1% | $75,307 | 29.9% | 245 | 7 | Screen Gems | - | false |
| 33 | The Lovely Bones | $241,989 | $170,986 | 70.7% | $71,003 | 29.3% | 263 | 13 | DreamWorks | - | false |
| 34 | The Young Victoria | $232,944 | $134,896 | 57.9% | $98,048 | 42.1% | 134 | 12 | Apparition | - | false |
| 35 | The White Ribbon | $209,564 | $140,774 | 67.2% | $68,790 | 32.8% | 106 | 11 | Sony Pictures Classics | - | false |
| 36 | The Oscar Nominated Short Films 2010: Live Action | $179,485 | $128,648 | 71.7% | $50,837 | 28.3% | 74 | 3 | Shorts International | - | false |
| 37 | Invictus | $176,133 | $121,276 | 68.8% | $54,857 | 31.2% | 188 | 13 | Warner Bros. | - | false |
| 38 | My Name Is Khan | $163,965 | $129,122 | 78.8% | $34,843 | 21.2% | 90 | 4 | Fox Searchlight Pictures | - | false |
| 39 | To Save a Life | $140,676 | $95,131 | 67.6% | $45,545 | 32.4% | 105 | 7 | The Samuel Goldwyn Company | - | false |
| 40 | Under the Sea 3D | $138,148 | $88,459 | 64% | $49,689 | 36% | 22 | 56 | Warner Bros. | - | false |
| 41 | Planet 51 | $120,843 | $95,314 | 78.9% | $25,529 | 21.1% | 354 | 16 | Sony Pictures Releasing | - | false |
| 42 | Space Station 3D | $80,308 | $41,596 | 51.8% | $38,712 | 48.2% | 6 | 412 | IMAX | - | false |
| 43 | Magnificent Desolation: Walking on the Moon | $75,687 | $31,136 | 41.1% | $44,551 | 58.9% | 5 | 233 | IMAX | - | false |
| 44 | Ajami | $73,366 | $53,241 | 72.6% | $20,125 | 27.4% | 21 | 6 | Kino International | - | false |
| 45 | Karthik Calling Karthik | $66,822 | $54,269 | 81.2% | $12,553 | 18.8% | 70 | 2 | Eros Worldwide | - | false |
| 46 | The Imaginarium of Doctor Parnassus | $59,274 | $37,848 | 63.8% | $21,426 | 36.2% | 71 | 11 | Sony Pictures Classics | - | false |
| 47 | The Secret of Kells | $54,503 | $39,826 | 73.1% | $14,677 | 26.9% | 1 | 1 | GKIDS | - | false |
| 48 | North Face | $49,095 | $34,809 | 70.9% | $14,286 | 29.1% | 25 | 6 | Music Box Films | - | false |
| 49 | Broken Embraces | $46,178 | $28,177 | 61% | $18,001 | 39% | 40 | 16 | Sony Pictures Classics | - | false |
| 50 | The Messenger | $45,294 | $32,118 | 70.9% | $13,176 | 29.1% | 32 | 17 | Oscilloscope | - | false |
| 51 | The Art of the Steal | $43,992 | $30,019 | 68.2% | $13,973 | 31.8% | 9 | 2 | IFC Films | - | false |
| 52 | The Yellow Handkerchief | $42,501 | $29,860 | 70.3% | $12,641 | 29.7% | 16 | 2 | The Samuel Goldwyn Company | - | false |
| 53 | Fantastic Mr. Fox | $38,835 | $26,794 | 69% | $12,041 | 31% | 47 | 17 | Twentieth Century Fox | - | false |
| 54 | The Most Dangerous Man in America: Daniel Ellsberg and the Pentagon Papers | $36,943 | $25,797 | 69.8% | $11,146 | 30.2% | 12 | 6 | First Run | - | false |
| 55 | The Weathered Underground | $34,408 | $32,164 | 93.5% | $2,244 | 6.5% | 22 | 7 | Indican Pictures | - | false |
| 56 | Formosa Betrayed | $30,860 | $21,765 | 70.5% | $9,095 | 29.5% | 16 | 2 | Screen Media Films | - | false |
| 57 | Sea Monsters: A Prehistoric Adventure | $30,668 | $20,611 | 67.2% | $10,057 | 32.8% | 8 | 127 | National Geographic Entertainment | - | false |
| 58 | The Secrets of Jonathan Sperry | $24,126 | $19,117 | 79.2% | $5,009 | 20.8% | 18 | 25 | Five & Two Pictures | - | false |
| 59 | Deep Sea | $23,543 | $17,167 | 72.9% | $6,376 | 27.1% | 4 | 210 | Warner Bros. | - | false |
| 60 | The Good Guy | $19,052 | $12,829 | 67.3% | $6,223 | 32.7% | 6 | 3 | Roadside Attractions | - | false |
| 61 | Fish Tank | $17,188 | $10,523 | 61.2% | $6,665 | 38.8% | 13 | 8 | IFC Films | - | false |
| 62 | Prodigal Sons | $16,146 | $10,827 | 67.1% | $5,319 | 32.9% | 5 | 2 | First Run | - | false |
| 63 | Nine | $15,814 | $9,552 | 60.4% | $6,262 | 39.6% | 46 | 12 | The Weinstein Company | - | false |
| 64 | Creation | $13,981 | $9,670 | 69.2% | $4,311 | 30.8% | 5 | 7 | Newmarket Films | - | false |
| 65 | Harlan: In the Shadow of Jew Suess | $13,782 | $9,258 | 67.2% | $4,524 | 32.8% | 1 | 2 | Zeitgeist Films | - | false |
| 66 | That Evening Sun | $13,331 | $9,069 | 68% | $4,262 | 32% | 7 | 18 | Freestyle Releasing | - | false |
| 67 | Preacher's Kid | $12,464 | $9,936 | 79.7% | $2,528 | 20.3% | 16 | 6 | 8x Entertainment | - | false |
| 68 | U2 3D | $12,289 | $9,641 | 78.4% | $2,648 | 21.6% | 1 | 112 | National Geographic Entertainment | - | false |
| 69 | Youth in Revolt | $11,810 | $8,082 | 68.4% | $3,728 | 31.6% | 12 | 9 | Dimension Films | - | false |
| 70 | The Road | $11,274 | $7,022 | 62.3% | $4,252 | 37.7% | 22 | 16 | Dimension Films | - | false |
| 71 | Red Riding: The Year of Our Lord 1974 | $10,995 | $6,738 | 61.3% | $4,257 | 38.7% | 5 | 5 | IFC Films | - | false |
| 72 | Dolphins and Whales 3D: Tribes of the Ocean | $9,979 | $7,676 | 76.9% | $2,303 | 23.1% | 7 | 108 | 3D Entertainment | - | false |
| 73 | Terribly Happy | $9,576 | $6,268 | 65.5% | $3,308 | 34.5% | 6 | 5 | Oscilloscope | - | false |
| 74 | Ran 2010 Re-release | $9,431 | $4,861 | 51.5% | $4,570 | 48.5% | 1 | 5 | Rialto Pictures | - | false |
| 75 | The Girl on the Train | $9,242 | $6,565 | 71% | $2,677 | 29% | 5 | 7 | Strand Releasing | - | false |
| 76 | The Maid | $8,447 | $5,008 | 59.3% | $3,439 | 40.7% | 4 | 21 | Elephant Eye Films | - | false |
| 77 | Red Cliff | $6,172 | $4,180 | 67.7% | $1,992 | 32.3% | 7 | 17 | Magnolia Pictures | - | false |
| 78 | Frozen | $6,064 | $3,743 | 61.7% | $2,321 | 38.3% | 5 | 5 | Anchor Bay Films | - | false |
| 79 | Until the Light Takes Us | $4,842 | $2,228 | 46% | $2,614 | 54% | 1 | 14 | Variance Films | - | false |
| 80 | The Sun 2009 Re-release | $4,735 | $4,735 | 100% | $0 | - | 3 | 17 | Lorber Films | - | false |
| 81 | District 13: Ultimatum | $4,163 | $2,550 | 61.2% | $1,613 | 38.8% | 5 | 5 | Magnolia Pictures | - | false |
| 82 | A Town Called Panic | $2,945 | $1,757 | 59.7% | $1,188 | 40.3% | 1 | 13 | Zeitgeist Films | - | false |
| 83 | House | $2,526 | $1,394 | 55.2% | $1,132 | 44.8% | 1 | 8 | Janus Films | - | false |
| 84 | Toe to Toe | $2,244 | $1,297 | 57.8% | $947 | 42.2% | 1 | 2 | Strand Releasing | - | false |
| 85 | The Private Lives of Pippa Lee | $2,032 | $2,032 | 100% | $0 | - | 3 | 15 | Screen Media Films | - | false |
| 86 | Seraphine | $1,876 | $1,209 | 64.4% | $667 | 35.6% | 3 | 40 | Music Box Films | - | false |
| 87 | Mystery Team | $1,869 | $1,869 | 100% | $0 | - | 1 | 28 | Roadside Attractions | - | false |
| 88 | Eyes Wide Open | $1,727 | $1,216 | 70.4% | $511 | 29.6% | 1 | 5 | New American Vision | - | false |
| 89 | The Korean | $1,593 | $1,304 | 81.9% | $289 | 18.1% | 1 | 5 | Indican Pictures | - | false |
| 90 | Dreamkiller | $1,460 | $1,404 | 96.2% | $56 | 3.8% | 1 | 3 | Delaware Pictures | - | false |
| 91 | The End of Poverty? | $1,258 | $458 | 36.4% | $800 | 63.6% | 2 | 17 | Cinema Libre Studio | - | false |
| 92 | La Danse: The Paris Opera Ballet | $1,181 | - | - | - | - | 3 | 19 | Zipporah Films | - | false |
| 93 | Sweetgrass | $1,166 | $382 | 32.8% | $784 | 67.2% | 1 | 10 | The Cinema Guild | - | false |
| 94 | 3 Idiots | $1,077 | $1,077 | 100% | $0 | - | 2 | 12 | Reliance Big Pictures | - | false |
| 95 | 35 Shots of Rum | $978 | $506 | 51.7% | $472 | 48.3% | 1 | 26 | The Cinema Guild | - | false |
| 96 | 44 Inch Chest 2010 Re-release | $904 | $480 | 53.1% | $424 | 46.9% | 1 | 8 | Image Entertainment | - | false |
| 97 | Yuri Gagarin Conspiracy: Fallen Idol | $770 | $557 | 72.3% | $213 | 27.7% | 1 | 23 | Indican Pictures | - | false |
| 98 | The Yes Men Fix the World | $600 | - | - | - | - | 2 | 24 | Shadow Distribution | - | false |
| 99 | The Beaches of Agnès | $561 | $561 | 100% | $0 | - | 1 | 37 | The Cinema Guild | - | false |
| 100 | Killing Kasztner | $505 | $228 | 45.2% | $277 | 54.8% | 1 | 20 | Sky Island Films | - | false |
| 101 | Amreeka | $503 | - | - | - | - | 1 | 27 | National Geographic Entertainment | - | false |
| 102 | 45365 | $391 | $312 | 79.8% | $79 | 20.2% | 1 | 2 | - | - | false |
| 103 | Small Change | $343 | $126 | 36.7% | $217 | 63.3% | 1 | 16 | The Film Desk | - | false |
| 104 | Monsieur Verdoux | $322 | $322 | 100% | $0 | - | 1 | 104 | The Film Desk | - | false |
| 105 | The Cove | $313 | $88 | 28.1% | $225 | 71.9% | 2 | 32 | Roadside Attractions | - | false |
| 106 | Off and Running | $304 | - | - | - | - | 1 | 6 | First Run | - | false |
| 107 | Box Elder | $274 | $274 | 100% | $0 | - | 1 | 106 | N/A | - | false |
| 108 | Happy Tears | $235 | $148 | 63% | $87 | 37% | 1 | 3 | Roadside Attractions | - | false |
| 109 | Home | $221 | $221 | 100% | $0 | - | 1 | 15 | Lorber Films | - | false |
| 110 | Beeswax | $181 | $96 | 53% | $85 | 47% | 1 | 31 | The Cinema Guild | - | false |
| 111 | The Wild Child | $134 | - | - | - | - | 1 | 70 | The Film Desk | - | false |
| 112 | Under Our Skin | $100 | - | - | - | - | 1 | 38 | Shadow Distribution | - | false |
| - | The Wedding Song | - | - | - | - | - | - | 22 | Strand Releasing | - | false |
| - | Videocracy | - | - | - | - | - | - | 4 | Kino International | - | false |
| - | Galapagos | - | - | - | - | - | - | 541 | IMAX | - | false |
| - | White on Rice | - | - | - | - | - | - | 26 | Variance Films | - | false |
| - | Four Seasons Lodge | - | - | - | - | - | - | 18 | First Run | - | false |
| - | October Country | - | - | - | - | - | - | 4 | International Film Circuit | - | false |
