| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Avatar | $42,020,936 | $31,280,029 | 74.4% | $10,740,907 | 25.6% | 3,074 | 7 | Twentieth Century Fox | - | false |
| 2 | Edge of Darkness | $22,092,480 | $17,214,384 | 77.9% | $4,878,096 | 22.1% | 3,066 | 1 | Warner Bros. | - | false |
| 3 | When in Rome | $15,395,605 | $12,350,041 | 80.2% | $3,045,564 | 19.8% | 2,456 | 1 | Walt Disney Studios Motion Pictures | - | false |
| 4 | Tooth Fairy | $11,726,695 | $9,998,109 | 85.3% | $1,728,586 | 14.7% | 3,345 | 2 | Twentieth Century Fox | - | false |
| 5 | The Book of Eli | $11,724,326 | $8,908,286 | 76% | $2,816,040 | 24% | 3,075 | 3 | Warner Bros. | - | false |
| 6 | Legion | $9,431,872 | $7,176,375 | 76.1% | $2,255,497 | 23.9% | 2,476 | 2 | Screen Gems | - | false |
| 7 | The Lovely Bones | $5,944,521 | $4,726,828 | 79.5% | $1,217,693 | 20.5% | 2,638 | 8 | DreamWorks | - | false |
| 8 | Sherlock Holmes | $5,863,118 | $4,515,344 | 77% | $1,347,774 | 23% | 2,250 | 6 | Warner Bros. | - | false |
| 9 | It's Complicated | $5,147,170 | $3,804,215 | 73.9% | $1,342,955 | 26.1% | 2,096 | 6 | Universal Pictures | - | false |
| 10 | Alvin and the Chipmunks: The Squeakquel | $4,732,354 | $3,997,136 | 84.5% | $735,218 | 15.5% | 2,526 | 7 | Twentieth Century Fox | - | false |
| 11 | The Blind Side | $4,132,881 | $3,021,317 | 73.1% | $1,111,564 | 26.9% | 1,751 | 11 | Warner Bros. | - | false |
| 12 | Up in the Air | $3,858,676 | $2,801,141 | 72.6% | $1,057,535 | 27.4% | 1,430 | 9 | Paramount Pictures | - | false |
| 13 | Extraordinary Measures | $3,506,578 | $2,619,257 | 74.7% | $887,321 | 25.3% | 2,549 | 2 | CBS Films | - | false |
| 14 | Crazy Heart | $3,189,596 | $2,309,245 | 72.4% | $880,351 | 27.6% | 239 | 8 | Fox Searchlight Pictures | - | false |
| 15 | The Spy Next Door | $2,474,395 | $2,075,020 | 83.9% | $399,375 | 16.1% | 1,851 | 3 | Lionsgate | - | false |
| 16 | Leap Year | $1,351,285 | $1,015,910 | 75.2% | $335,375 | 24.8% | 1,135 | 4 | Universal Pictures | - | false |
| 17 | The Princess and the Frog | $1,006,503 | $800,570 | 79.5% | $205,933 | 20.5% | 728 | 11 | Walt Disney Studios Motion Pictures | - | false |
| 18 | Daybreakers | $961,682 | $699,338 | 72.7% | $262,344 | 27.3% | 725 | 4 | Lionsgate | - | false |
| 19 | To Save a Life | $941,684 | $733,457 | 77.9% | $208,227 | 22.1% | 440 | 2 | The Samuel Goldwyn Company | - | false |
| 20 | The Young Victoria | $862,490 | $584,399 | 67.8% | $278,091 | 32.2% | 390 | 7 | Apparition | - | false |
| 21 | A Single Man | $822,910 | $553,019 | 67.2% | $269,891 | 32.8% | 216 | 8 | The Weinstein Company | - | false |
| 22 | The Twilight Saga: New Moon | $598,080 | $435,545 | 72.8% | $162,535 | 27.2% | 352 | 11 | Summit Entertainment | - | false |
| 23 | The Imaginarium of Doctor Parnassus | $456,027 | $322,908 | 70.8% | $133,119 | 29.2% | 179 | 6 | Sony Pictures Classics | - | false |
| 24 | Youth in Revolt | $385,865 | $281,382 | 72.9% | $104,483 | 27.1% | 246 | 4 | Dimension Films | - | false |
| 25 | Invictus | $374,139 | $270,900 | 72.4% | $103,239 | 27.6% | 225 | 8 | Warner Bros. | - | false |
| 26 | Precious | $350,295 | $215,131 | 61.4% | $135,164 | 38.6% | 222 | 13 | Lionsgate | - | false |
| 27 | Planet 51 | $345,298 | $281,698 | 81.6% | $63,600 | 18.4% | 282 | 11 | Sony Pictures Releasing | - | false |
| 28 | Nine | $320,559 | $208,672 | 65.1% | $111,887 | 34.9% | 220 | 7 | The Weinstein Company | - | false |
| 29 | Broken Embraces | $316,356 | $226,173 | 71.5% | $90,183 | 28.5% | 160 | 11 | Sony Pictures Classics | - | false |
| 30 | 2012 | $307,727 | $232,557 | 75.6% | $75,170 | 24.4% | 272 | 12 | Sony Pictures Releasing | - | false |
| 31 | Preacher's Kid | $241,671 | $190,638 | 78.9% | $51,033 | 21.1% | 109 | 1 | 8x Entertainment | - | false |
| 32 | An Education | $183,305 | $119,146 | 65% | $64,159 | 35% | 75 | 17 | Sony Pictures Classics | - | false |
| 33 | Fantastic Mr. Fox | $178,354 | $136,850 | 76.7% | $41,504 | 23.3% | 152 | 12 | Twentieth Century Fox | - | false |
| 34 | The White Ribbon | $164,663 | $116,866 | 71% | $47,797 | 29% | 22 | 6 | Sony Pictures Classics | - | false |
| 35 | The Last Station | $128,454 | $84,745 | 66% | $43,709 | 34% | 9 | 3 | Sony Pictures Classics | - | false |
| 36 | Under the Sea 3D | $126,392 | $82,374 | 65.2% | $44,018 | 34.8% | 27 | 51 | Warner Bros. | - | false |
| 37 | Old Dogs | $115,873 | $91,492 | 79% | $24,381 | 21% | 111 | 11 | Walt Disney Studios Motion Pictures | - | false |
| 38 | Veer | $110,957 | $92,336 | 83.2% | $18,621 | 16.8% | 92 | 2 | Eros Worldwide | - | false |
| 39 | Couples Retreat | $108,695 | $79,965 | 73.6% | $28,730 | 26.4% | 144 | 17 | Universal Pictures | - | false |
| 40 | 3 Idiots | $99,268 | $81,475 | 82.1% | $17,793 | 17.9% | 56 | 7 | Reliance Big Pictures | - | false |
| 41 | The Road | $92,646 | $61,343 | 66.2% | $31,303 | 33.8% | 90 | 11 | Dimension Films | - | false |
| 42 | Ninja Assassin | $84,703 | $60,346 | 71.2% | $24,357 | 28.8% | 132 | 11 | Warner Bros. | - | false |
| 43 | Fish Tank | $71,208 | $49,606 | 69.7% | $21,602 | 30.3% | 13 | 3 | IFC Films | - | false |
| 44 | Space Station 3D | $69,143 | $31,978 | 46.2% | $37,165 | 53.8% | 8 | 407 | IMAX | - | false |
| 45 | Where the Wild Things Are | $65,096 | $49,634 | 76.2% | $15,462 | 23.8% | 109 | 16 | Warner Bros. | - | false |
| 46 | Magnificent Desolation: Walking on the Moon | $57,087 | $25,272 | 44.3% | $31,815 | 55.7% | 7 | 228 | IMAX | - | false |
| 47 | Creation | $54,699 | $39,994 | 73.1% | $14,705 | 26.9% | 12 | 2 | Newmarket Films | - | false |
| 48 | Bad Lieutenant: Port of Call New Orleans | $48,789 | $31,225 | 64% | $17,564 | 36% | 46 | 11 | First Look International | - | false |
| 49 | Law Abiding Citizen | $45,563 | $31,249 | 68.6% | $14,314 | 31.4% | 78 | 16 | Overture Films | - | false |
| 50 | The Most Dangerous Man in America: Daniel Ellsberg and the Pentagon Papers | $39,062 | $1,114 | 2.8% | $37,948 | 97.2% | 1 | 1 | First Run | - | false |
| 51 | The Men Who Stare at Goats | $37,244 | $25,158 | 67.6% | $12,086 | 32.4% | 72 | 13 | Overture Films | - | false |
| 52 | North Face | $33,972 | $23,050 | 67.8% | $10,922 | 32.2% | 4 | 1 | Music Box Films | - | false |
| 53 | The Boondock Saints II: All Saints Day | $33,379 | $21,079 | 63.2% | $12,300 | 36.8% | 43 | 14 | Apparition | - | false |
| 54 | The Messenger | $31,083 | $17,951 | 57.8% | $13,132 | 42.2% | 28 | 12 | Oscilloscope | - | false |
| 55 | The Girl on the Train | $30,063 | $20,672 | 68.8% | $9,391 | 31.2% | 10 | 2 | Strand Releasing | - | false |
| 56 | Saint John of Las Vegas | $28,404 | $21,666 | 76.3% | $6,738 | 23.7% | 2 | 1 | IndieVest Pictures | - | false |
| 57 | Me and Orson Welles | $27,015 | $16,756 | 62% | $10,259 | 38% | 23 | 11 | Freestyle Releasing | - | false |
| 58 | Sea Monsters: A Prehistoric Adventure | $26,395 | $14,240 | 54% | $12,155 | 46% | 8 | 122 | National Geographic Entertainment | - | false |
| 59 | A Christmas Carol | $25,008 | $19,241 | 76.9% | $5,767 | 23.1% | 66 | 13 | Walt Disney Studios Motion Pictures | - | false |
| 60 | Coco Before Chanel | $23,971 | $13,780 | 57.5% | $10,191 | 42.5% | 52 | 19 | Sony Pictures Classics | - | false |
| 61 | A Town Called Panic | $22,298 | $16,485 | 73.9% | $5,813 | 26.1% | 6 | 8 | Zeitgeist Films | - | false |
| 62 | That Evening Sun | $19,669 | $12,187 | 62% | $7,482 | 38% | 9 | 13 | Freestyle Releasing | - | false |
| 63 | The Secrets of Jonathan Sperry | $16,704 | $13,803 | 82.6% | $2,901 | 17.4% | 8 | 20 | Five & Two Pictures | - | false |
| 64 | Deep Sea | $16,236 | $13,802 | 85% | $2,434 | 15% | 2 | 205 | Warner Bros. | - | false |
| 65 | Dolphins and Whales 3D: Tribes of the Ocean | $15,299 | $7,111 | 46.5% | $8,188 | 53.5% | 5 | 103 | 3D Entertainment | - | false |
| 66 | Red Cliff | $14,366 | $10,502 | 73.1% | $3,864 | 26.9% | 14 | 12 | Magnolia Pictures | - | false |
| 67 | 44 Inch Chest 2010 Re-release | $12,524 | $7,893 | 63% | $4,631 | 37% | 4 | 3 | Image Entertainment | - | false |
| 68 | Off and Running | $11,967 | $7,978 | 66.7% | $3,989 | 33.3% | 1 | 1 | First Run | - | false |
| 69 | The Private Lives of Pippa Lee | $11,514 | $7,930 | 68.9% | $3,584 | 31.1% | 8 | 10 | Screen Media Films | - | false |
| 70 | Until the Light Takes Us | $9,028 | $6,376 | 70.6% | $2,652 | 29.4% | 3 | 9 | Variance Films | - | false |
| 71 | The Maid | $8,751 | $5,912 | 67.6% | $2,839 | 32.4% | 7 | 16 | Elephant Eye Films | - | false |
| 72 | Killing Kasztner | $8,148 | $6,357 | 78% | $1,791 | 22% | 5 | 15 | Sky Island Films | - | false |
| 73 | 35 Shots of Rum | $7,393 | $6,464 | 87.4% | $929 | 12.6% | 4 | 21 | The Cinema Guild | - | false |
| 74 | House | $6,595 | $3,876 | 58.8% | $2,719 | 41.2% | 1 | 3 | Janus Films | - | false |
| 75 | Mystery Team | $6,003 | $2,392 | 39.8% | $3,611 | 60.2% | 4 | 23 | Roadside Attractions | - | false |
| 76 | Ajami | $4,356 | - | - | - | - | 1 | 1 | Kino International | - | false |
| 77 | Seraphine | $3,800 | $2,566 | 67.5% | $1,234 | 32.5% | 2 | 35 | Music Box Films | - | false |
| 78 | The Beaches of Agnès | $3,565 | $1,381 | 38.7% | $2,184 | 61.3% | 2 | 32 | The Cinema Guild | - | false |
| 79 | The Damned United | $3,529 | $2,035 | 57.7% | $1,494 | 42.3% | 5 | 17 | Sony Pictures Classics | - | false |
| 80 | Waiting for Armageddon | $3,504 | $2,412 | 68.8% | $1,092 | 31.2% | 1 | 4 | First Run | - | false |
| 81 | Bliss 2009 Re-release | $2,856 | $1,710 | 59.9% | $1,146 | 40.1% | 1 | 26 | First Run | - | false |
| 82 | Sweetgrass | $2,822 | $2,235 | 79.2% | $587 | 20.8% | 3 | 5 | The Cinema Guild | - | false |
| 83 | The Horse Boy | $1,869 | $1,616 | 86.5% | $253 | 13.5% | 1 | 19 | Zeitgeist Films | - | false |
| 84 | Galapagos | $1,623 | $1,088 | 67% | $535 | 33% | 1 | 536 | IMAX | - | false |
| 85 | The Weathered Underground | $1,490 | $1,010 | 67.8% | $480 | 32.2% | 3 | 2 | Indican Pictures | - | false |
| 86 | Big Fan | $1,176 | $1,176 | 100% | $0 | - | 1 | 23 | First Independent Pictures | - | false |
| 87 | Cloud 9 | $999 | $941 | 94.2% | $58 | 5.8% | 2 | 25 | Music Box Films | - | false |
| 88 | Falling Awake | $847 | $847 | 100% | $0 | - | 1 | 1 | IFC Films | - | false |
| 89 | The Sun 2009 Re-release | $788 | - | - | - | - | 1 | 12 | Lorber Films | - | false |
| 90 | The End of Poverty? | $773 | $773 | 100% | $0 | - | 2 | 12 | Cinema Libre Studio | - | false |
| 91 | The Yes Men Fix the World | $742 | $384 | 51.8% | $358 | 48.2% | 4 | 19 | Shadow Distribution | - | false |
| 92 | Misconceptions | $687 | $425 | 61.9% | $262 | 38.1% | 1 | 2 | Regent Releasing | - | false |
| 93 | Amreeka | $624 | - | - | - | - | 1 | 22 | National Geographic Entertainment | - | false |
| 94 | Fashion Victim | $600 | $600 | 100% | $0 | - | 1 | 2 | Regent Releasing | - | false |
| 95 | Watercolors | $550 | $550 | 100% | $0 | - | 1 | 2 | Regent Releasing | - | false |
| 96 | Good Hair | $543 | - | - | - | - | 1 | 17 | Roadside Attractions | - | false |
| 97 | Departures | $359 | $150 | 41.8% | $209 | 58.2% | 2 | 36 | Regent Releasing | - | false |
| 98 | Trucker | $263 | - | - | - | - | 1 | 17 | Monterey Media | - | false |
| - | La Danse: The Paris Opera Ballet | - | - | - | - | - | - | 14 | Zipporah Films | - | false |
| - | The Wedding Song | - | - | - | - | - | - | 17 | Strand Releasing | - | false |
| - | U2 3D | - | - | - | - | - | - | 107 | National Geographic Entertainment | - | false |
| - | The September Issue | - | - | - | - | - | - | 23 | Roadside Attractions | - | false |
| - | Beeswax | - | - | - | - | - | - | 26 | The Cinema Guild | - | false |
| - | Four Seasons Lodge | - | - | - | - | - | - | 13 | First Run | - | false |
| - | Youssou Ndour: I Bring What I Love | - | - | - | - | - | - | 34 | Shadow Distribution | - | false |
| - | Shall We Kiss? | - | - | - | - | - | - | 45 | Music Box Films | - | false |
| - | Small Change | - | - | - | - | - | - | 11 | The Film Desk | - | false |
