| TW | LW | Total | %± LW | Share | Releases | #1 Release
| Gross | % of Total | Week | Distributor
| New This Week
|
|---|
| 1 | 9 | $164,964,071 | +8,471.1% | 60.2% | 3 | Avatar | $137,094,001 | 83.1% | 1 | Twentieth Century Fox | - |
| 2 | 1 | $33,314,276 | -26.2% | 12.2% | 3 | The Princess and the Frog | $22,142,907 | 66.5% | 5 | Walt Disney Studios Motion Pictures | - |
| 3 | 2 | $27,167,283 | -24.7% | 9.9% | 8 | The Blind Side | $17,972,391 | 66.2% | 5 | Warner Bros. | - |
| 4 | 5 | $16,226,808 | +82.4% | 5.9% | 4 | Did You Hear About the Morgans? | $10,600,185 | 65.3% | 1 | Sony Pictures Releasing | - |
| 5 | 7 | $7,906,673 | +125.3% | 2.9% | 2 | Up in the Air | $7,755,801 | 98.1% | 3 | Paramount Pictures | - |
| 6 | 3 | $7,886,375 | -27.6% | 2.9% | 2 | The Twilight Saga: New Moon | $7,727,778 | 98% | 5 | Summit Entertainment | - |
| 7 | 4 | $6,703,768 | -25% | 2.4% | 2 | Brothers | $4,670,602 | 69.7% | 3 | Lionsgate | - |
| 8 | 6 | $2,011,721 | -57.4% | 0.7% | 1 | Armored | $2,011,721 | 100% | 3 | Screen Gems | - |
| 9 | 11 | $1,163,863 | +53.1% | 0.4% | 1 | The Road | $1,163,863 | 100% | 5 | Dimension Films | - |
| 10 | 10 | $1,143,019 | -10.5% | 0.4% | 2 | The Boondock Saints II: All Saints Day | $688,441 | 60.2% | 8 | Apparition | - |
| 11 | 8 | $954,889 | -69.4% | 0.3% | 1 | Everybody's Fine | $954,889 | 100% | 3 | Miramax | - |
| 12 | 22 | $793,052 | +807.3% | 0.3% | 2 | Magnificent Desolation: Walking on the Moon | $706,075 | 89% | 222 | IMAX | - |
| 13 | 12 | $738,095 | +4.9% | 0.3% | 4 | An Education | $367,497 | 49.8% | 11 | Sony Pictures Classics | - |
| 14 | 16 | $613,602 | +64.2% | 0.2% | 2 | Nine | $378,072 | 61.6% | 1 | The Weinstein Company | - |
| 16 | 14 | $391,070 | -29.9% | 0.1% | 2 | Couples Retreat | $279,390 | 71.4% | 11 | Universal Pictures | - |
| 17 | 13 | $304,512 | -46.9% | 0.1% | 2 | The Men Who Stare at Goats | $152,847 | 50.2% | 7 | Overture Films | - |
| 18 | 15 | $290,989 | -40.2% | 0.1% | 2 | A Serious Man | $180,073 | 61.9% | 12 | Focus Features | - |
| 19 | 17 | $274,849 | +20.6% | 0.1% | 2 | Me and Orson Welles | $274,076 | 99.7% | 5 | Freestyle Releasing | - |
| 20 | 21 | $171,991 | +92.9% | <0.1% | 2 | Crazy Heart | $139,246 | 81% | 2 | Fox Searchlight Pictures | - |
| 21 | 18 | $108,583 | -51.6% | <0.1% | 1 | Bad Lieutenant: Port of Call New Orleans | $108,583 | 100% | 5 | First Look International | - |
| 22 | 19 | $78,655 | -49.4% | <0.1% | 1 | The Lovely Bones | $78,655 | 100% | 2 | DreamWorks | - |
| 23 | 20 | $73,600 | -39% | <0.1% | 5 | Red Cliff | $62,325 | 84.7% | 6 | Magnolia Pictures | - |
| 24 | 23 | $43,788 | -36.9% | <0.1% | 1 | The Messenger | $43,788 | 100% | 6 | Oscilloscope | - |
| 25 | 24 | $41,415 | -34.7% | <0.1% | 1 | La Danse: The Paris Opera Ballet | $41,415 | 100% | 8 | Zipporah Films | - |
| 26 | 25 | $27,524 | -46.3% | <0.1% | 1 | The Private Lives of Pippa Lee | $27,524 | 100% | 4 | Screen Media Films | - |
| 27 | 31 | $26,108 | -0.7% | <0.1% | 1 | The Maid | $26,108 | 100% | 10 | Elephant Eye Films | - |
| 28 | 28 | $25,715 | -23.5% | <0.1% | 1 | Sea Monsters: A Prehistoric Adventure | $25,715 | 100% | 116 | National Geographic Entertainment | - |
| 29 | 26 | $21,383 | -54.2% | <0.1% | 4 | Paris | $10,057 | 47% | 14 | IFC Films | - |
| 30 | 29 | $8,224 | -70.8% | <0.1% | 1 | New York, I Love You | $8,224 | 100% | 10 | Vivendi Entertainment | - |
| 31 | 36 | $8,004 | -25.5% | <0.1% | 3 | 35 Shots of Rum | $5,319 | 66.5% | 15 | The Cinema Guild | - |
| 32 | 39 | $7,411 | -6.1% | <0.1% | 2 | A Town Called Panic | $5,250 | 70.8% | 2 | Zeitgeist Films | - |
| 33 | 49 | $5,460 | +158.8% | <0.1% | 3 | Cloud 9 | $2,940 | 53.8% | 19 | Music Box Films | - |
| 34 | 34 | $5,073 | -67.9% | <0.1% | 1 | Until the Light Takes Us | $5,073 | 100% | 3 | Variance Films | - |
| 35 | 50 | $4,913 | +141.1% | <0.1% | 1 | Yoo-Hoo, Mrs. Goldberg | $4,913 | 100% | 24 | International Film Circuit | - |
| 36 | 30 | $4,165 | -84.3% | <0.1% | 3 | The September Issue | $2,077 | 49.9% | 17 | Roadside Attractions | - |
| 37 | 38 | $3,999 | -54% | <0.1% | 1 | Killing Kasztner | $3,999 | 100% | 9 | Sky Island Films | - |
| 39 | 42 | $3,335 | -43.9% | <0.1% | 1 | Dolphins and Whales 3D: Tribes of the Ocean | $3,335 | 100% | 97 | 3D Entertainment | - |
| 40 | 48 | $2,441 | +11.7% | <0.1% | 2 | Home | $1,430 | 58.6% | 4 | Lorber Films | - |
| 41 | 35 | $2,373 | -79.4% | <0.1% | 2 | Four Seasons Lodge | $2,261 | 95.3% | 7 | First Run | - |
| 42 | 46 | $1,948 | -13.2% | <0.1% | 1 | The End of Poverty? | $1,948 | 100% | 6 | Cinema Libre Studio | - |
| 43 | 27 | $1,941 | -94.7% | <0.1% | 1 | The Slammin' Salmon | $1,941 | 100% | 2 | Anchor Bay Films | - |
| 44 | 45 | $1,688 | -38.9% | <0.1% | 1 | Oh My God | $1,688 | 100% | 6 | Mitropoulos Films | - |
| 45 | 37 | $1,496 | -84.4% | <0.1% | 1 | Kurbaan | $1,496 | 100% | 5 | UTV Motion Pictures | - |
| 46 | 43 | $1,205 | -76.7% | <0.1% | 3 | The Headless Woman | $728 | 60.4% | 19 | Strand Releasing | - |
| 47 | 44 | $920 | -76.6% | <0.1% | 1 | Endgame | $920 | 100% | 7 | Monterey Media | - |
| 48 | 52 | $229 | -75.8% | <0.1% | 1 | Big Fan | $229 | 100% | 17 | First Independent Pictures | - |
| 49 | 53 | $222 | +4.7% | <0.1% | 1 | Departures | $222 | 100% | 30 | Regent Releasing | - |
