| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Apocalypto | $59,570 | - | - | - | - | 20 | 3 | 20th Century Fox International | - | false |
| 2 | Curse of the Golden Flower | $47,373 | - | - | - | - | 13 | 1 | Sony Pictures Releasing | - | false |
| 3 | Arthur and the Invisibles | $46,937 | - | - | - | - | 25 | 2 | Bazuca Films | - | false |
| 4 | Music and Lyrics | $45,129 | - | - | - | - | 27 | 2 | Warner Bros. | - | false |
| 5 | Night at the Museum | $37,047 | - | - | - | - | 34 | 10 | 20th Century Fox International | - | false |
| 6 | Borat | $31,178 | - | - | - | - | 8 | 2 | 20th Century Fox International | - | false |
| 7 | The Holiday | $28,277 | - | - | - | - | 23 | 5 | United International Pictures | - | false |
| 8 | Norbit | $26,800 | - | - | - | - | 22 | 3 | United International Pictures | - | false |
| 9 | Pan's Labyrinth | $23,748 | - | - | - | - | 6 | 5 | Warner Bros. | - | false |
| 10 | Blood Diamond | $22,087 | - | - | - | - | 24 | 8 | Warner Bros. | - | false |
| 11 | The Departed | $14,677 | - | - | - | - | 19 | 19 | Warner Bros. | - | false |
| 12 | Notes on a Scandal | $14,154 | - | - | - | - | 5 | 4 | 20th Century Fox International | - | false |
| 13 | Babel | $13,386 | - | - | - | - | 10 | 10 | United International Pictures | - | false |
| 14 | The Pursuit of Happyness | $13,213 | - | - | - | - | 11 | 7 | Sony Pictures Releasing | - | false |
| 15 | The Illusionist | $12,815 | - | - | - | - | 12 | 11 | Transeuropa | - | false |
| 16 | The Last King of Scotland | $9,908 | - | - | - | - | 4 | 6 | 20th Century Fox International | - | false |
| 17 | Letters from Iwo Jima | $8,030 | - | - | - | - | 7 | 6 | Warner Bros. | - | false |
| 18 | Me and You and Everyone We Know | $6,586 | - | - | - | - | 3 | 1 | Four Films | - | false |
| 19 | Flushed Away | $5,409 | - | - | - | - | 6 | 15 | United International Pictures | - | false |
| 20 | The Tiger and the Snow | $4,800 | - | - | - | - | 8 | 5 | Bazuca Films | - | false |
