| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Night at the Museum | $167,773 | - | - | - | - | 54 | 5 | 20th Century Fox International | - | false |
| 2 | Babel | $83,286 | - | - | - | - | 32 | 5 | United International Pictures | - | false |
| 3 | Blood Diamond | $75,236 | - | - | - | - | 23 | 3 | Warner Bros. | - | false |
| 4 | Rocky Balboa | $72,852 | - | - | - | - | 39 | 2 | 20th Century Fox International | - | false |
| 5 | Letters from Iwo Jima | $50,834 | - | - | - | - | 10 | 1 | Warner Bros. | - | false |
| 6 | The Pursuit of Happyness | $44,528 | - | - | - | - | 11 | 2 | Sony Pictures Releasing | - | false |
| 7 | The Illusionist | $39,448 | - | - | - | - | 14 | 6 | Transeuropa | - | false |
| 8 | Deja Vu | $27,199 | - | - | - | - | 13 | 6 | Buena Vista International | - | false |
| 9 | Charlotte's Web | $26,244 | - | - | - | - | 18 | 6 | United International Pictures | - | false |
| 10 | Flushed Away | $25,511 | - | - | - | - | 16 | 10 | United International Pictures | - | false |
| 11 | The Last King of Scotland | $23,064 | - | - | - | - | 5 | 1 | 20th Century Fox International | - | false |
| 12 | Eragon | $16,441 | - | - | - | - | 14 | 7 | 20th Century Fox International | - | false |
| 13 | Children of Men | $16,105 | - | - | - | - | 14 | 4 | United International Pictures | - | false |
| 14 | Flags of Our Fathers | $14,385 | - | - | - | - | 10 | 4 | Warner Bros. | - | false |
| 15 | Dreamgirls | $13,105 | - | - | - | - | 7 | 1 | United International Pictures | - | false |
| 16 | Cry Wolf | $11,562 | - | - | - | - | 9 | 3 | Bazuca Films | - | false |
| 17 | Little Miss Sunshine | $10,428 | - | - | - | - | 4 | 9 | 20th Century Fox International | - | false |
| 18 | The Departed | $9,255 | - | - | - | - | 5 | 14 | Warner Bros. | - | false |
| 19 | Marie Antoinette | $8,873 | - | - | - | - | 4 | 6 | Sony Pictures Releasing | - | false |
| 20 | Happy Feet | $4,309 | - | - | - | - | 6 | 12 | Warner Bros. | - | false |
