| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | John Tucker Must Die | $344,897 | - | - | - | - | 47 | 2 | - | - | false |
| 2 | The Pursuit of Happyness | $333,274 | - | - | - | - | 52 | 2 | Sony Pictures Releasing | - | false |
| 3 | Night at the Museum | $273,633 | - | - | - | - | 88 | 5 | - | - | false |
| 4 | The Queen | $163,286 | - | - | - | - | 26 | 3 | Filmladen | - | false |
| 5 | Charlotte's Web | $157,265 | - | - | - | - | 61 | 2 | Universal Pictures International (UPI) | - | false |
| 6 | Babel | $154,148 | - | - | - | - | 20 | 6 | Constantin Film | - | false |
| 7 | The Holiday | $141,811 | - | - | - | - | 84 | 7 | United International Pictures | - | false |
| 8 | My Führer | $137,653 | - | - | - | - | 19 | 2 | Filmladen | - | false |
| 9 | Deja Vu | $112,480 | - | - | - | - | 75 | 5 | Buena Vista International | - | false |
| 10 | The Texas Chainsaw Massacre: The Beginning | $94,982 | - | - | - | - | 16 | 2 | Warner Bros. | - | false |
| 11 | The Departed | $91,459 | - | - | - | - | 65 | 8 | Warner Bros. | - | false |
| 12 | The Prestige | $75,419 | - | - | - | - | 24 | 4 | Warner Bros. | - | false |
| 13 | Grave Decisions | $71,124 | - | - | - | - | 30 | 11 | Luna Filmverleih | - | false |
| 14 | Flags of Our Fathers | $56,959 | - | - | - | - | 23 | 2 | Warner Bros. | - | false |
| 15 | Casino Royale | $53,314 | - | - | - | - | 46 | 10 | Sony Pictures Releasing | - | false |
| 16 | Flushed Away | $43,821 | - | - | - | - | 74 | 8 | United International Pictures | - | false |
| 17 | Eragon | $39,166 | - | - | - | - | 65 | 7 | 20th Century Fox International | - | false |
| 18 | Happy Feet | $38,243 | - | - | - | - | 74 | 9 | Warner Bros. | - | false |
| 19 | Apocalypto | $26,862 | - | - | - | - | 35 | 7 | Constantin Film | - | false |
| 20 | Hoodwinked | $14,442 | - | - | - | - | 34 | 6 | Luna Filmverleih | - | false |
