| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Apocalypto | $2,365,480 | - | 300 | - | $7,884 | $2,594,667 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Perfume: The Story of a Murderer | $655,893 | -57.9% | 201 | +1 | $3,263 | $2,191,956 | 2 | Gussi Films | false | false |
| 3 | 2 | Night at the Museum | $652,315 | -57.1% | 388 | -292 | $1,681 | $17,675,515 | 6 | 20th Century Fox International | false | false |
| 4 | 3 | Rocky Balboa | $374,112 | -70.5% | 278 | - | $1,345 | $4,022,725 | 3 | 20th Century Fox International | false | false |
| 5 | 4 | The Holiday | $300,924 | -63.8% | 250 | - | $1,203 | $2,357,118 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 5 | Fuera del cielo | $278,529 | -62.1% | 156 | +6 | $1,785 | $2,109,429 | 3 | Videocine | false | false |
| 7 | 6 | Tired of Kissing Frogs | $261,491 | -63.6% | 244 | -44 | $1,071 | $6,171,219 | 7 | Buena Vista International | false | false |
| 8 | - | Babel | $233,727 | - | 169 | - | $1,383 | $6,636,011 | 12 | United International Pictures | false | false |
| 9 | - | Dreamgirls | $220,114 | - | 120 | - | $1,834 | $220,114 | 1 | Paramount Pictures International | true | false |
| 10 | 9 | Unaccompanied Minors | $117,385 | -47.9% | 120 | -18 | $978 | $1,169,655 | 6 | Warner Bros. | false | false |
| 11 | 7 | Eragon | $112,872 | -70% | 153 | -97 | $737 | $10,327,811 | 7 | 20th Century Fox International | false | false |
| 12 | - | Flags of Our Fathers | $106,184 | - | 89 | - | $1,193 | $106,184 | 1 | Warner Bros. | true | false |
| 13 | - | The Texas Chainsaw Massacre: The Beginning | $100,241 | - | 125 | - | $801 | $100,241 | 1 | Gussi Films | true | false |
| 14 | 8 | Flushed Away | $100,218 | -61.2% | 127 | -74 | $789 | $6,268,590 | 7 | United International Pictures | false | false |
| 15 | 10 | Charlotte's Web | $87,013 | -58.7% | 129 | -71 | $674 | $2,018,071 | 5 | United International Pictures | false | false |
| 16 | - | Saint Ange 2006 Re-release | $70,358 | - | 69 | - | $1,019 | $555,830 | 5 | Gussi Films | false | false |
| 17 | 12 | Material Girls | $66,823 | -64.4% | 83 | -33 | $805 | $1,511,731 | 7 | Videocine | false | false |
| 18 | 16 | Pulse | $54,522 | -62.7% | 58 | -2 | $940 | $1,095,005 | 15 | Gussi Films | false | false |
| 19 | 13 | The Wicker Man | $52,612 | -70.5% | 63 | -7 | $835 | $1,000,719 | 12 | Gussi Films | false | false |
| 20 | 15 | Lucky Number Slevin | $43,559 | -71.2% | 51 | -13 | $854 | $995,778 | 14 | Gussi Films | false | false |
