| TW | LW | Total | %± LW | Share | Releases | #1 Release
| Gross | % of Total | Week | Distributor
| New This Week
|
|---|
| 1 | 2 | $99,135,801 | +177.4% | 29.6% | 7 | Night at the Museum | $79,055,249 | 79.7% | 1 | Twentieth Century Fox | - |
| 2 | 1 | $62,341,223 | +2.6% | 18.6% | 3 | The Pursuit of Happyness | $40,762,334 | 65.4% | 2 | Sony Pictures Releasing | - |
| 3 | 3 | $42,959,740 | +37.4% | 12.8% | 10 | We Are Marshall | $15,938,381 | 37.1% | 1 | Warner Bros. | - |
| 4 | 6 | $34,986,824 | +247.1% | 10.5% | 5 | Rocky Balboa | $27,674,960 | 79.1% | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 6 | 9 | $22,360,690 | +2,147.6% | 6.7% | 3 | Dreamgirls | $22,340,320 | 99.9% | 2 | DreamWorks | - |
| 7 | 5 | $22,048,351 | +17.2% | 6.6% | 1 | Charlotte's Web | $22,048,351 | 100% | 2 | Paramount Pictures | - |
| 8 | 4 | $11,737,325 | -39.2% | 3.5% | 8 | Apocalypto | $7,665,282 | 65.3% | 3 | Walt Disney Studios Motion Pictures | - |
| 9 | 7 | $8,378,077 | -2.3% | 2.5% | 4 | The Nativity Story | $8,084,923 | 96.5% | 4 | New Line Cinema | - |
| 10 | 11 | $1,819,797 | +245% | 0.5% | 5 | Volver | $1,108,198 | 60.9% | 8 | Sony Pictures Classics | - |
| 11 | 12 | $995,344 | +97.6% | 0.3% | 5 | The History Boys | $664,147 | 66.7% | 6 | Fox Searchlight Pictures | - |
| 12 | 10 | $784,178 | +6.4% | 0.2% | 1 | Babel | $784,178 | 100% | 9 | Paramount Vantage | - |
| 13 | 8 | $555,901 | -47.7% | 0.2% | 2 | The Queen | $482,475 | 86.8% | 13 | Miramax | - |
| 15 | 16 | $414,699 | +41.8% | 0.1% | 3 | Magnificent Desolation: Walking on the Moon | $250,737 | 60.5% | 66 | IMAX | - |
| 16 | 14 | $228,950 | -23.7% | <0.1% | 2 | For Your Consideration | $116,727 | 51% | 6 | Warner Independent Pictures (WIP) | - |
| 17 | 15 | $143,751 | -52% | <0.1% | 2 | Kabul Express | $80,251 | 55.8% | 2 | Yash Raj Films | - |
| 18 | 22 | $105,158 | +95.1% | <0.1% | 1 | Sweet Land | $105,158 | 100% | 11 | Libero | - |
| 19 | 17 | $95,552 | -64.1% | <0.1% | 1 | Guadalupe: El Milagro Y El Mensaje | $95,552 | 100% | 3 | Slowhand Cinema Releasing | - |
| 20 | 13 | $71,616 | -83% | <0.1% | 1 | Turistas | $71,616 | 100% | 4 | Fox Atomic | - |
| 21 | 18 | $55,768 | -34.5% | <0.1% | 1 | The Wedding Weekend | $55,768 | 100% | 9 | The Weinstein Company | - |
| 22 | 23 | $48,637 | +27.1% | <0.1% | 1 | The Work and the Glory III: A House Divided | $48,637 | 100% | 6 | Excel Entertainment | - |
| 23 | 21 | $42,304 | -24.1% | <0.1% | 1 | The Illusionist | $42,304 | 100% | 19 | Yari Film Group Releasing | - |
| 24 | 20 | $40,062 | -42.1% | <0.1% | 1 | Facing the Giants | $40,062 | 100% | 13 | IDP Distribution | - |
| 25 | 19 | $30,740 | -60.8% | <0.1% | 4 | Shortbus | $17,226 | 56% | 13 | THINKFilm | - |
| 26 | 25 | $22,000 | -12.7% | <0.1% | 1 | Wild Safari - A South African Adventure | $22,000 | 100% | 90 | nWave Pictures | - |
| 27 | 24 | $14,630 | -43% | <0.1% | 3 | Family Law | $6,503 | 44.4% | 4 | IFC Films | - |
| 28 | 26 | $13,738 | -39.8% | <0.1% | 3 | Jesus Camp | $9,856 | 71.7% | 15 | Magnolia Pictures | - |
| 29 | 29 | $11,971 | -2.2% | <0.1% | 4 | The Secret Life of Words | $9,127 | 76.2% | 2 | Strand Releasing | - |
| 30 | 37 | $11,299 | +152.4% | <0.1% | 2 | 2 or 3 Things I Know About Her | $9,679 | 85.7% | 6 | Rialto Pictures | - |
| 32 | 27 | $9,513 | -30.9% | <0.1% | 1 | The Young Lieutenant | $9,513 | 100% | 16 | The Cinema Guild | - |
| 33 | 28 | $7,566 | -43.9% | <0.1% | 1 | Screamers | $7,566 | 100% | 3 | Maya Entertainment | - |
| 34 | 35 | $4,748 | -9.9% | <0.1% | 1 | Mrs Palfrey at the Claremont | $4,748 | 100% | 57 | Cineville | - |
| 35 | 31 | $4,595 | -41.5% | <0.1% | 1 | The Cave of the Yellow Dog | $4,595 | 100% | 7 | Tartan | - |
| 36 | 39 | $2,247 | -30.2% | <0.1% | 1 | Flannel Pajamas | $2,247 | 100% | 7 | Gigantic Pictures | - |
| 37 | 38 | $1,702 | -61.7% | <0.1% | 1 | The Bridge | $1,702 | 100% | 9 | First Stripe Productions | - |
| 38 | 30 | $720 | -94% | <0.1% | 1 | El Topo | $720 | 100% | 3 | ABKCO Films | - |
| 39 | 33 | $626 | -91% | <0.1% | 1 | The Bridesmaid | $626 | 100% | 21 | First Run | - |
| 40 | 44 | $184 | -59.9% | <0.1% | 1 | Mutual Appreciation | $184 | 100% | 17 | Goodbye Cruel Releasing | - |
