| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Holiday | $590,591 | - | 93 | - | $6,350 | $590,591 | 2 | United International Pictures | false | false |
| 2 | - | Eragon | $536,652 | - | 85 | - | $6,313 | $596,171 | 2 | 20th Century Fox International | false | false |
| 3 | 1 | Casino Royale | $357,791 | -56.6% | 86 | -13 | $4,160 | $4,776,700 | 5 | Sony Pictures Releasing | false | false |
| 4 | 2 | The Departed | $337,544 | -49.7% | 64 | +1 | $5,274 | $1,058,583 | 3 | Warner Bros. | false | false |
| 5 | 3 | Happy Feet | $229,026 | -35.7% | 84 | +2 | $2,726 | $945,894 | 4 | Warner Bros. | false | false |
| 6 | 4 | Flushed Away | $205,627 | -33.8% | 71 | - | $2,896 | $532,078 | 3 | United International Pictures | false | false |
| 7 | - | Apocalypto | $120,952 | - | 23 | - | $5,258 | $120,952 | 2 | Constantin Film | false | false |
| 8 | 6 | The Santa Clause 3: The Escape Clause | $56,048 | -21.3% | 67 | - | $836 | $491,426 | 8 | Buena Vista International | false | false |
| 9 | 10 | Grave Decisions | $38,133 | -29.1% | 27 | -1 | $1,412 | $347,825 | 6 | Luna Filmverleih | false | false |
| 10 | 8 | Borat | $33,422 | -48.3% | 49 | -5 | $682 | $1,597,225 | 8 | - | false | false |
| 11 | 5 | Open Season | $32,602 | -55.1% | 94 | -2 | $346 | $1,209,211 | 7 | Sony Pictures Releasing | false | false |
| 12 | 7 | Jackass Number Two | $28,149 | -57.3% | 22 | - | $1,279 | $180,437 | 4 | United International Pictures | false | false |
| 13 | 14 | Pettson & Findus - Tomtemaskinen | $26,625 | -14.5% | 30 | - | $887 | $107,825 | 5 | Filmladen | false | false |
| 14 | 9 | 7 Dwarves: The Forest Is Not Enough | $26,276 | -55.9% | 53 | -10 | $495 | $3,929,500 | 9 | United International Pictures | false | false |
| 15 | 12 | Little Miss Sunshine | $24,661 | -25.4% | 14 | - | $1,761 | $104,635 | 4 | - | false | false |
| 16 | 16 | The Nativity Story | $16,534 | -41.2% | 38 | +3 | $435 | $45,987 | 3 | Warner Bros. | false | false |
| 17 | 15 | Scoop | $15,804 | -48.4% | 9 | - | $1,756 | $232,244 | 6 | Constantin Film | false | false |
| 18 | 17 | A Friend of Mine | $14,493 | -19.9% | 9 | -1 | $1,610 | $32,425 | 3 | Filmladen | false | false |
| 19 | 11 | The Devil Wears Prada | $13,851 | -60.8% | 35 | -9 | $395 | $3,528,701 | 11 | - | false | false |
| 20 | - | Turks in Space | $13,850 | - | 6 | - | $2,308 | $13,850 | 2 | Maxximum Film und Kunst GmbH | false | false |
