| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | The Pursuit of Happyness | $38,286,895 | $26,541,709 | 69.3% | $11,745,186 | 30.7% | 2,852 | 1 | Sony Pictures Releasing | - | false |
| 2 | Eragon | $30,495,702 | $23,239,907 | 76.2% | $7,255,795 | 23.8% | 3,020 | 1 | Twentieth Century Fox | - | false |
| 3 | Charlotte's Web | $18,809,466 | $11,457,353 | 60.9% | $7,352,113 | 39.1% | 3,566 | 1 | Paramount Pictures | - | false |
| 4 | Happy Feet | $13,069,793 | $8,358,421 | 64% | $4,711,372 | 36% | 3,335 | 5 | Warner Bros. | - | false |
| 5 | The Holiday | $12,982,623 | $8,014,713 | 61.7% | $4,967,910 | 38.3% | 2,614 | 2 | Sony Pictures Releasing | - | false |
| 6 | Apocalypto | $11,522,750 | $8,008,126 | 69.5% | $3,514,624 | 30.5% | 2,465 | 2 | Walt Disney Studios Motion Pictures | - | false |
| 7 | Blood Diamond | $9,882,964 | $6,517,471 | 66% | $3,365,493 | 34% | 1,910 | 2 | Warner Bros. | - | false |
| 8 | Rocky Balboa | $9,693,214 | - | - | - | - | 2,752 | 1 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 9 | Casino Royale | $8,695,660 | $5,627,644 | 64.7% | $3,068,016 | 35.3% | 2,214 | 5 | Sony Pictures Releasing | - | false |
| 10 | The Nativity Story | $8,328,512 | $4,700,000 | - | - | - | 2,574 | 3 | New Line Cinema | - | true |
| 11 | Unaccompanied Minors | $5,451,352 | $3,545,352 | 65% | $1,906,000 | 35% | 2,708 | 2 | Warner Bros. | - | false |
| 12 | Deja Vu | $4,345,790 | $2,975,356 | 68.5% | $1,370,434 | 31.5% | 1,985 | 5 | Walt Disney Studios Motion Pictures | - | false |
| 13 | The Santa Clause 3: The Escape Clause | $3,125,988 | $1,895,591 | 60.6% | $1,230,397 | 39.4% | 1,535 | 7 | Walt Disney Studios Motion Pictures | - | false |
| 14 | Deck the Halls | $2,702,553 | $1,921,123 | 71.1% | $781,430 | 28.9% | 1,260 | 5 | Twentieth Century Fox | - | false |
| 15 | Borat | $2,414,284 | $1,543,840 | 64% | $870,444 | 36% | 730 | 7 | Twentieth Century Fox | - | false |
| 16 | We Are Marshall | $1,100,000 | - | - | - | - | - | - | Warner Bros. | - | false |
| 17 | The Queen | $1,057,433 | $685,000 | - | - | - | 483 | 12 | Miramax | - | true |
| 18 | Stranger Than Fiction | $815,036 | $517,622 | 63.5% | $297,414 | 36.5% | 423 | 6 | Sony Pictures Releasing | - | false |
| 19 | Babel | $737,121 | $495,750 | 67.2% | $241,371 | 32.8% | 220 | 8 | Paramount Vantage | - | false |
| 20 | The Polar Express 2006 IMAX Release | $719,117 | $391,328 | 54.4% | $327,789 | 45.6% | 37 | 5 | Warner Bros. | - | false |
| 21 | Dreamgirls | $624,025 | $378,950 | 60.7% | $245,075 | 39.3% | 3 | 1 | DreamWorks | - | false |
| 22 | The Departed | $549,150 | $341,300 | 62.2% | $207,850 | 37.8% | 191 | 11 | Warner Bros. | - | false |
| 23 | Volver | $473,000 | $313,413 | 66.3% | $159,587 | 33.7% | 45 | 7 | Sony Pictures Classics | - | false |
| 24 | Turistas | $420,806 | $299,709 | 71.2% | $121,097 | 28.8% | 375 | 3 | Fox Atomic | - | false |
| 25 | Flushed Away | $370,829 | $245,207 | 66.1% | $125,622 | 33.9% | 450 | 7 | DreamWorks | - | false |
| 26 | The History Boys | $332,056 | $219,532 | 66.1% | $112,524 | 33.9% | 76 | 5 | Fox Searchlight Pictures | - | false |
| 27 | Guadalupe: El Milagro Y El Mensaje | $266,124 | $216,105 | 81.2% | $50,019 | 18.8% | 110 | 2 | Slowhand Cinema Releasing | - | false |
| 28 | For Your Consideration | $263,274 | $172,958 | 65.7% | $90,316 | 34.3% | 161 | 5 | Warner Independent Pictures (WIP) | - | false |
| 29 | Bobby | $231,289 | $155,050 | 67% | $76,239 | 33% | 203 | 5 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 30 | The Fountain | $210,066 | $130,233 | 62% | $79,833 | 38% | 35 | 5 | Warner Bros. | - | false |
| 31 | Santa vs. the Snowman 3D 2006 Re-release | $191,074 | $96,519 | 50.5% | $94,555 | 49.5% | 29 | 8 | IMAX | - | false |
| 32 | Kabul Express | $175,447 | $142,591 | 81.3% | $32,856 | 18.7% | 50 | 1 | Yash Raj Films | - | false |
| 33 | Deep Sea | $132,156 | $62,311 | 47.2% | $69,845 | 52.8% | 25 | 42 | Warner Bros. | - | false |
| 34 | Dhoom 2 | $123,874 | $109,763 | 88.6% | $14,111 | 11.4% | 40 | 5 | Yash Raj Films | - | false |
| 35 | Little Children | $119,715 | $77,587 | 64.8% | $42,128 | 35.2% | 21 | 11 | New Line Cinema | - | false |
| 36 | The Good German | $118,578 | $76,817 | 64.8% | $41,761 | 35.2% | 5 | 1 | Warner Bros. | - | false |
| 37 | The Prestige | $104,718 | $58,699 | 56% | $46,019 | 44% | 116 | 9 | Walt Disney Studios Motion Pictures | - | false |
| 38 | Little Miss Sunshine | $101,039 | $58,074 | 57.5% | $42,965 | 42.5% | 95 | 22 | Fox Searchlight Pictures | - | false |
| 39 | Van Wilder: The Rise of Taj | $94,791 | $63,874 | 67.4% | $30,917 | 32.6% | 130 | 3 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 40 | Magnificent Desolation: Walking on the Moon | $87,768 | $34,111 | 38.9% | $53,657 | 61.1% | 11 | 65 | IMAX | - | false |
| 41 | Tenacious D in the Pick of Destiny | $86,661 | $54,663 | 63.1% | $31,998 | 36.9% | 160 | 5 | New Line Cinema | - | false |
| 42 | The Guardian | $86,445 | $53,822 | 62.3% | $32,623 | 37.7% | 168 | 12 | Walt Disney Studios Motion Pictures | - | false |
| 43 | The Wedding Weekend | $85,177 | $48,914 | 57.4% | $36,263 | 42.6% | 83 | 8 | The Weinstein Company | - | false |
| 44 | Facing the Giants | $69,206 | $49,013 | 70.8% | $20,193 | 29.2% | 123 | 12 | IDP Distribution | - | false |
| 45 | Flicka | $68,940 | $48,098 | 69.8% | $20,842 | 30.2% | 189 | 9 | Twentieth Century Fox | - | false |
| 46 | Roving Mars | $56,926 | $36,120 | 63.4% | $20,806 | 36.6% | 19 | 47 | Walt Disney Studios Motion Pictures | - | false |
| 47 | The Illusionist | $55,771 | $35,492 | 63.6% | $20,279 | 36.4% | 82 | 18 | Yari Film Group Releasing | - | false |
| 48 | Sweet Land | $53,905 | $35,074 | 65.1% | $18,831 | 34.9% | 21 | 10 | Libero | - | false |
| 49 | The Last King of Scotland | $51,558 | $33,206 | 64.4% | $18,352 | 35.6% | 15 | 13 | Fox Searchlight Pictures | - | false |
| 50 | The Nightmare Before Christmas 2006 3D Release | $48,534 | $25,606 | 52.8% | $22,928 | 47.2% | 6 | 9 | Walt Disney Studios Motion Pictures | - | false |
| 51 | Letters from Iwo Jima | $39,745 | - | - | - | - | 5 | 1 | Warner Bros. | - | false |
| 52 | The Marine | $38,974 | $27,386 | 70.3% | $11,588 | 29.7% | 84 | 10 | Twentieth Century Fox | - | false |
| 53 | The Work and the Glory III: A House Divided | $38,277 | $22,083 | 57.7% | $16,194 | 42.3% | 15 | 5 | Excel Entertainment | - | false |
| 54 | The Texas Chainsaw Massacre: The Beginning | $36,601 | $23,507 | 64.2% | $13,094 | 35.8% | 68 | 11 | New Line Cinema | - | false |
| 55 | Shortbus | $34,797 | $20,173 | 58% | $14,624 | 42% | 22 | 12 | THINKFilm | - | false |
| 56 | Copying Beethoven | $26,936 | $18,524 | 68.8% | $8,412 | 31.2% | 23 | 6 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 57 | A Good Year | $23,314 | $13,624 | 58.4% | $9,690 | 41.6% | 61 | 6 | Twentieth Century Fox | - | false |
| 58 | Flyboys | $21,162 | $12,820 | 60.6% | $8,342 | 39.4% | 63 | 13 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 59 | The Painted Veil | $21,144 | - | - | - | - | 4 | 1 | Warner Independent Pictures (WIP) | - | false |
| 60 | Wild Safari - A South African Adventure | $20,000 | $8,200 | 41% | $11,800 | 59% | 6 | 89 | nWave Pictures | - | false |
| 61 | Keeping Mum | $19,743 | $11,717 | 59.4% | $8,026 | 40.6% | 16 | 14 | THINKFilm | - | false |
| 62 | Driving Lessons | $19,120 | $10,875 | 56.9% | $8,245 | 43.1% | 19 | 10 | Sony Pictures Classics | - | false |
| 63 | Fast Food Nation | $19,043 | $11,292 | 59.3% | $7,751 | 40.7% | 24 | 5 | Fox Searchlight Pictures | - | false |
| 64 | American Hardcore | $15,776 | $8,905 | 56.4% | $6,871 | 43.6% | 17 | 13 | Sony Pictures Classics | - | false |
| 65 | Curse of the Golden Flower | $14,144 | - | - | - | - | 2 | 1 | Sony Pictures Classics | - | false |
| 66 | The Science of Sleep | $13,858 | $7,023 | 50.7% | $6,835 | 49.3% | 12 | 13 | Warner Independent Pictures (WIP) | - | false |
| 67 | The Young Lieutenant | $13,774 | $9,595 | 69.7% | $4,179 | 30.3% | 3 | 15 | The Cinema Guild | - | false |
| 68 | Screamers | $13,486 | $7,700 | 57.1% | $5,786 | 42.9% | 3 | 2 | Maya Entertainment | - | false |
| 69 | Jesus Camp | $13,109 | $8,442 | 64.4% | $4,667 | 35.6% | 14 | 14 | Magnolia Pictures | - | false |
| 70 | Candy | $12,364 | $7,124 | 57.6% | $5,240 | 42.4% | 12 | 5 | THINKFilm | - | false |
| 71 | El Topo | $11,926 | $6,857 | 57.5% | $5,069 | 42.5% | 1 | 2 | ABKCO Films | - | false |
| 72 | School for Scoundrels | $11,771 | $7,998 | 68% | $3,773 | 32% | 40 | 12 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 73 | Galapagos | $11,057 | $4,520 | 40.9% | $6,537 | 59.1% | 2 | 373 | IMAX | - | false |
| 74 | The Secret Life of Words | $7,986 | $5,309 | 66.5% | $2,677 | 33.5% | 1 | 1 | Strand Releasing | - | false |
| 75 | The Cave of the Yellow Dog | $7,857 | $5,212 | 66.3% | $2,645 | 33.7% | 8 | 6 | Tartan | - | false |
| 76 | 10 Items or Less | $7,062 | $5,187 | 73.4% | $1,875 | 26.6% | 4 | 3 | THINKFilm | - | false |
| 77 | The Aura | $6,959 | $4,608 | 66.2% | $2,351 | 33.8% | 2 | 6 | IFC Films | - | false |
| 78 | Fur: An Imaginary Portrait of Diane Arbus | $6,948 | $4,660 | 67.1% | $2,288 | 32.9% | 9 | 6 | Picturehouse | - | false |
| 79 | The Bridesmaid | $6,943 | $5,307 | 76.4% | $1,636 | 23.6% | 6 | 20 | First Run | - | false |
| 80 | This Film Is Not Yet Rated | $6,287 | $1,621 | 25.8% | $4,666 | 74.2% | 6 | 16 | IFC Films | - | false |
| 81 | Venus | $5,763 | - | - | - | - | 3 | 1 | Miramax | - | false |
| 82 | Family Law | $5,614 | $4,055 | 72.2% | $1,559 | 27.8% | 3 | 3 | IFC Films | - | false |
| 83 | Eating Out 2: Sloppy Seconds | $5,533 | $2,050 | 37% | $3,483 | 63% | 2 | 4 | Ariztical Entertainment | - | false |
| 84 | Riding Alone for Thousands of Miles | $5,498 | $3,688 | 67.1% | $1,810 | 32.9% | 10 | 16 | Sony Pictures Classics | - | false |
| 85 | Mrs Palfrey at the Claremont | $5,270 | $3,145 | 59.7% | $2,125 | 40.3% | 5 | 56 | Cineville | - | false |
| 86 | Black Gold | $5,169 | $3,126 | 60.5% | $2,043 | 39.5% | 4 | 11 | California Newsreel | - | false |
| 87 | Aliens of the Deep | $4,930 | $1,019 | 20.7% | $3,911 | 79.3% | 2 | 99 | Walt Disney Studios Motion Pictures | - | false |
| 88 | Unknown | $4,920 | $3,203 | 65.1% | $1,717 | 34.9% | 4 | 7 | IFC Films | - | false |
| 89 | Army of Shadows | $4,477 | $2,805 | 62.6% | $1,672 | 37.4% | 5 | 34 | Rialto Pictures | - | false |
| 90 | The Bridge | $4,440 | $2,867 | 64.6% | $1,573 | 35.4% | 2 | 8 | First Stripe Productions | - | false |
| 91 | Off the Black | $4,431 | $2,832 | 63.9% | $1,599 | 36.1% | 4 | 2 | THINKFilm | - | false |
| 92 | Haunted Castle | $3,500 | $2,250 | 64.3% | $1,250 | 35.7% | 2 | 304 | nWave Pictures | - | false |
| 93 | Cocaine Cowboys | $3,361 | $1,934 | 57.5% | $1,427 | 42.5% | 5 | 8 | Magnolia Pictures | - | false |
| 94 | The Architect | $3,314 | $2,221 | 67% | $1,093 | 33% | 5 | 3 | Magnolia Pictures | - | false |
| 95 | Flannel Pajamas | $3,219 | $2,438 | 75.7% | $781 | 24.3% | 1 | 6 | Gigantic Pictures | - | false |
| 96 | Samoan Wedding | $3,047 | $1,921 | 63% | $1,126 | 37% | 2 | 6 | Magnolia Pictures | - | false |
| 97 | Space Station 3D | $2,245 | $624 | 27.8% | $1,621 | 72.2% | 2 | 244 | IMAX | - | false |
| 98 | Home of the Brave | $2,040 | $6,000 | 294.1% | $-3,960 | - | 3 | 1 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 99 | Infamous | $1,905 | $978 | 51.3% | $927 | 48.7% | 4 | 10 | Warner Independent Pictures (WIP) | - | false |
| 100 | Matthew Barney: No Restraint | $1,879 | - | - | - | - | 2 | 1 | IFC Films | - | false |
| 101 | Old Joy | $1,706 | $765 | 44.8% | $941 | 55.2% | 5 | 17 | Kino International | - | false |
| 102 | Backstage | $1,371 | $725 | 52.9% | $646 | 47.1% | 1 | 5 | Strand Releasing | - | false |
| 103 | Paper Dolls | $1,319 | $831 | 63% | $488 | 37% | 2 | 16 | Strand Releasing | - | false |
| 104 | Opal Dream | $1,250 | $400 | 32% | $850 | 68% | 1 | 5 | Strand Releasing | - | false |
| 105 | Climates | $1,146 | $726 | 63.4% | $420 | 36.6% | 2 | 8 | Zeitgeist Films | - | false |
| 106 | Screen Door Jesus | $1,112 | $504 | 45.3% | $608 | 54.7% | 1 | 64 | Indican Pictures | - | false |
| 107 | Abduction: The Megumi Yokota Story | $958 | $631 | 65.9% | $327 | 34.1% | 1 | 4 | Sagewood Cinema Ventures | - | false |
| 108 | Encounter in the Third Dimension | $901 | $510 | 56.6% | $391 | 43.4% | 1 | 408 | nWave Pictures | - | false |
| 109 | Alien Adventure | $801 | $505 | 63% | $296 | 37% | 1 | 383 | nWave Pictures | - | false |
| 110 | Mutual Appreciation | $459 | $459 | 100% | $0 | - | 1 | 16 | Goodbye Cruel Releasing | - | false |
| 111 | Time to Leave | $309 | $204 | 66% | $105 | 34% | 1 | 22 | Strand Releasing | - | false |
| 112 | Captain Sabertooth 2006 Re-release | $307 | $307 | 100% | $0 | - | 1 | 13 | Indican Pictures | - | false |
| 113 | T-Rex: Back to the Cretaceous | $250 | $250 | 100% | $0 | - | 1 | 426 | IMAX | - | false |
| - | Breaking and Entering | - | - | - | - | - | 1 | 1 | The Weinstein Company | - | false |
| - | Ever Again | - | - | - | - | - | 1 | 2 | Rocky Mountain Pictures | - | false |
| - | 2 or 3 Things I Know About Her | - | - | - | - | - | - | 5 | Rialto Pictures | - | false |
| - | A Soap | - | - | - | - | - | - | 7 | Strand Releasing | - | false |
