| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Wayne's World | $10,990,661 | -10.8% | 1,878 | - | $5,852 | $59,807,282 | 4 | Paramount Pictures | false | false |
| 2 | - | The Lawnmower Man | $10,345,092 | - | 1,276 | - | $8,107 | $10,345,092 | 1 | New Line Cinema | true | false |
| 3 | 3 | Fried Green Tomatoes | $5,304,035 | -9% | 1,331 | +2 | $3,985 | $53,804,779 | 11 | Universal Pictures | false | false |
| 4 | - | Once Upon a Crime... | $4,237,616 | - | 1,101 | - | $3,848 | $4,237,616 | 1 | Metro-Goldwyn-Mayer (MGM) | true | false |
| 5 | - | Gladiator | $4,073,567 | - | 1,295 | - | $3,145 | $4,073,567 | 1 | Columbia Pictures | true | false |
| 6 | 4 | Stop! Or My Mom Will Shoot | $4,043,270 | -27.1% | 1,958 | - | $2,065 | $18,136,075 | 3 | Universal Pictures | false | false |
| 7 | 2 | Memoirs of an Invisible Man | $3,608,562 | -39.2% | 1,753 | - | $2,058 | $9,546,893 | 2 | Warner Bros. | false | false |
| 8 | 5 | Medicine Man | $3,493,175 | -23.5% | 1,282 | -81 | $2,724 | $35,303,876 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 9 | 6 | The Hand That Rocks the Cradle | $3,387,956 | -24.9% | 1,590 | -89 | $2,130 | $74,079,408 | 9 | Walt Disney Studios Motion Pictures | false | false |
| 10 | 8 | Beauty and the Beast | $2,379,423 | -10.3% | 1,253 | -93 | $1,898 | $118,937,354 | 17 | Walt Disney Studios Motion Pictures | false | false |
| 11 | 7 | Final Analysis | $2,010,949 | -35% | 1,010 | -373 | $1,991 | $25,543,679 | 5 | Warner Bros. | false | false |
| 12 | - | Blame It on the Bellboy | $1,690,030 | - | 462 | - | $3,658 | $1,690,030 | 1 | Walt Disney Studios Motion Pictures | true | false |
| 13 | 9 | The Prince of Tides | $1,510,604 | -23.1% | 914 | -249 | $1,652 | $68,342,528 | 11 | Columbia Pictures | false | false |
| 14 | 10 | Mississippi Masala | $1,454,258 | -25.9% | 335 | +10 | $4,341 | $4,499,874 | 6 | The Samuel Goldwyn Company | false | false |
| 15 | 20 | This Is My Life | $823,173 | +105.4% | 125 | +94 | $6,585 | $1,330,704 | 3 | Twentieth Century Fox | false | false |
| 16 | 18 | Hook | $470,232 | -41.9% | 504 | -215 | $933 | $115,152,744 | 14 | TriStar Pictures | false | false |
| 17 | 19 | The Mambo Kings | $418,495 | -8.1% | 31 | -1 | $13,499 | $873,751 | 2 | Warner Bros. | false | false |
| 18 | - | Terminal Bliss | $215,500 | - | 356 | - | $605 | $215,500 | 1 | Cannon Film Distributors | true | false |
