| Rank | Release
| Weekly | Weekend | % of Week | Weekdays | % of Week | Theaters | Week | Distributor
| New This Week
| Estimated
|
|---|
| 1 | Rain Man | $8,852,344 | $6,829,705 | 77.2% | $2,022,639 | 22.8% | 1,563 | 7 | Metro-Goldwyn-Mayer (MGM) | - | false |
| 2 | Three Fugitives | $8,139,350 | $6,434,717 | 79.1% | $1,704,633 | 20.9% | 1,153 | 1 | Walt Disney Studios Motion Pictures | - | false |
| 3 | Beaches | $6,523,499 | $4,939,903 | 75.7% | $1,583,596 | 24.3% | 1,097 | 6 | Walt Disney Studios Motion Pictures | - | false |
| 4 | Twins | $5,731,845 | $4,802,805 | 83.8% | $929,040 | 16.2% | 1,659 | 8 | Universal Pictures | - | false |
| 5 | Mississippi Burning | $4,598,174 | $3,545,305 | 77.1% | $1,052,869 | 22.9% | 1,058 | 8 | Orion Pictures | - | false |
| 6 | Working Girl | $3,954,041 | $3,004,374 | 76% | $949,667 | 24% | 1,149 | 6 | Twentieth Century Fox | - | false |
| 7 | The Naked Gun: From the Files of Police Squad! | $3,558,339 | $2,868,339 | 80.6% | $690,000 | 19.4% | 1,501 | 9 | Paramount Pictures | - | false |
| 8 | The Accidental Tourist | $3,195,885 | $2,561,533 | 80.2% | $634,352 | 19.8% | 926 | 6 | Warner Bros. | - | false |
| 9 | Physical Evidence | $2,272,030 | $1,777,358 | 78.2% | $494,672 | 21.8% | 691 | 1 | Columbia Pictures | - | false |
| 10 | Dirty Rotten Scoundrels | $2,090,672 | $1,637,651 | 78.3% | $453,021 | 21.7% | 1,313 | 7 | Orion Pictures | - | false |
| 11 | Dangerous Liaisons | $1,773,219 | $1,300,240 | 73.3% | $472,979 | 26.7% | 119 | 6 | Warner Bros. | - | false |
| 12 | Oliver & Company | $1,238,205 | $1,054,889 | 85.2% | $183,316 | 14.8% | 1,316 | 11 | Walt Disney Studios Motion Pictures | - | false |
| 13 | Parents | $354,249 | $277,952 | 78.5% | $76,297 | 21.5% | 94 | 1 | Vestron Pictures | - | false |
| 14 | Cohen and Tate | $58,673 | $45,586 | 77.7% | $13,087 | 22.3% | 75 | 1 | Hemdale | - | false |
| 15 | Manifesto | $14,202 | $9,838 | 69.3% | $4,364 | 30.7% | 1 | 1 | Cannon Film Distributors | - | false |
| - | Torch Song Trilogy | - | - | - | - | - | 135 | 7 | New Line Cinema | - | false |
| - | Talk Radio | - | - | - | - | - | - | 6 | Universal Pictures | - | false |
| - | Vincent | - | - | - | - | - | - | 24 | Roxie Releasing | - | false |
| - | I'm Gonna Git You Sucka | - | - | - | - | - | - | 7 | United Artists | - | false |
| - | Gleaming the Cube | - | - | - | - | - | - | 3 | Twentieth Century Fox | - | false |
| - | The Land Before Time | - | - | - | - | - | - | 11 | Universal Pictures | - | false |
| - | Rachel River | - | - | - | - | - | - | 2 | Taurus Entertainment Company | - | false |
| - | The Chocolate War | - | - | - | - | - | - | 11 | Management Company Entertainment Group (MCEG) | - | false |
| - | DeepStar Six | - | - | - | - | - | - | 3 | TriStar Pictures | - | false |
| - | Tequila Sunrise | - | - | - | - | - | - | 9 | Warner Bros. | - | false |
| - | The January Man | - | - | - | - | - | - | 3 | Metro-Goldwyn-Mayer (MGM) | - | false |
