| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Taken | $24,625,000 | $24,717,037 | +$92,037 | +0.4% | 3,183 | $24,625,000 | $24,717,037 | 1 | Twentieth Century Fox | - |
| 2 | 2 | - | Paul Blart: Mall Cop | $14,000,000 | $13,872,751 | -$127,249 | -0.9% | 3,206 | $83,375,000 | $83,247,655 | 3 | Sony Pictures Releasing | - |
| 3 | 3 | - | The Uninvited | $10,512,000 | $10,325,824 | -$186,176 | -1.8% | 2,344 | $10,512,000 | $10,325,824 | 1 | DreamWorks | - |
| 4 | 4 | - | Hotel for Dogs | $8,706,000 | $8,632,740 | -$73,260 | -0.8% | 3,160 | $48,229,000 | $48,156,061 | 3 | DreamWorks | - |
| 5 | 5 | - | Gran Torino | $8,600,000 | $8,232,278 | -$367,722 | -4.3% | 3,015 | $110,547,000 | $110,178,990 | 8 | Warner Bros. | - |
| 6 | 6 | - | Slumdog Millionaire | $7,680,000 | $7,628,713 | -$51,287 | -0.7% | 1,633 | $67,244,000 | $67,193,169 | 12 | - | - |
| 7 | 7 | - | Underworld: Rise of the Lycans | $7,200,000 | $7,581,272 | +$381,272 | +5.3% | 2,942 | $32,784,000 | $33,165,746 | 2 | Screen Gems | - |
| 8 | 8 | - | New in Town | $6,750,000 | $6,741,530 | -$8,470 | -0.1% | 1,941 | $6,750,000 | $6,741,530 | 1 | Lionsgate Films | - |
| 9 | 9 | - | My Bloody Valentine | $4,260,000 | $4,479,662 | +$219,662 | +5.2% | 1,406 | $44,608,000 | $44,827,233 | 3 | Lionsgate Films | - |
| 10 | 10 | - | Inkheart | $3,700,000 | $3,721,492 | +$21,492 | +0.6% | 2,655 | $12,792,000 | $12,813,023 | 2 | Warner Bros. | - |
| 11 | 11 | - | The Curious Case of Benjamin Button | $3,611,000 | $3,544,251 | -$66,749 | -1.8% | 2,126 | $116,540,000 | $116,473,266 | 6 | Paramount Pictures | - |
| 12 | 12 | - | Bride Wars | $3,570,000 | $3,524,896 | -$45,104 | -1.3% | 1,985 | $53,937,000 | $53,891,483 | 4 | Twentieth Century Fox | - |
| 13 | 13 | - | Revolutionary Road | $2,659,000 | $2,674,320 | +$15,320 | +0.6% | 1,077 | $16,038,000 | $16,054,024 | 6 | Paramount Vantage | - |
| 14 | 14 | - | Defiance | $2,533,000 | $2,503,514 | -$29,486 | -1.2% | 1,662 | $22,830,000 | $22,800,595 | 5 | Paramount Vantage | - |
| 15 | 15 | - | The Reader | $2,374,000 | $2,380,376 | +$6,376 | +0.3% | 1,002 | $12,649,000 | $12,655,858 | 8 | The Weinstein Company | - |
| 16 | 16 | - | The Wrestler | $2,350,000 | $2,313,149 | -$36,851 | -1.6% | 722 | $13,089,000 | $13,051,867 | 7 | - | - |
| 17 | 17 | - | Notorious | $1,700,000 | $1,700,301 | +$301 | <0.1% | 1,080 | $35,011,000 | $35,011,149 | 3 | - | - |
| 18 | 18 | - | Milk | $1,414,000 | $1,481,155 | +$67,155 | +4.7% | 882 | $23,416,000 | $23,464,697 | 10 | Focus Features | - |
| 19 | 19 | - | Frost/Nixon | $1,398,000 | $1,403,550 | +$5,550 | +0.4% | 1,105 | $14,311,000 | $14,316,246 | 9 | Universal Pictures | - |
| 20 | 21 | +1 | The Unborn | $1,216,000 | $1,222,980 | +$6,980 | +0.6% | 1,308 | $41,312,000 | $41,318,365 | 4 | Universal Pictures | - |
| 21 | 20 | -1 | Last Chance Harvey | $1,187,000 | $1,227,208 | +$40,208 | +3.4% | 893 | $11,654,000 | $11,694,498 | 6 | Overture Films | - |
| 22 | 22 | - | Marley & Me | $945,000 | $960,224 | +$15,224 | +1.6% | 1,022 | $139,778,000 | $139,793,037 | 6 | Twentieth Century Fox | - |
| 23 | 23 | - | Doubt | $801,000 | $836,997 | +$35,997 | +4.5% | 602 | $27,949,000 | $27,984,891 | 8 | Miramax | - |
| 24 | 24 | - | Twilight | $585,000 | $623,836 | +$38,836 | +6.6% | 413 | $186,972,000 | $187,010,870 | 11 | Summit Entertainment | - |
| 25 | 25 | - | Bedtime Stories | $580,000 | $555,488 | -$24,512 | -4.2% | 639 | $108,591,000 | $108,566,034 | 6 | Walt Disney Studios Motion Pictures | - |
| 26 | 27 | +1 | Valkyrie | $405,000 | $402,518 | -$2,482 | -0.6% | 509 | $81,622,000 | $81,619,482 | 6 | United Artists | - |
| 27 | 29 | +2 | Madagascar: Escape 2 Africa | $335,000 | $326,479 | -$8,521 | -2.5% | 275 | $179,291,000 | $179,282,122 | 13 | DreamWorks | - |
| 28 | 31 | +3 | Rachel Getting Married | $248,000 | $223,075 | -$24,925 | -10.1% | 220 | $11,685,000 | $11,659,863 | 18 | Sony Pictures Classics | - |
| 29 | 33 | +4 | Yes Man | $200,000 | $208,017 | +$8,017 | +4% | 277 | $95,840,000 | $95,848,155 | 7 | Warner Bros. | - |
| 30 | 35 | +5 | Waltz with Bashir | $186,000 | $157,155 | -$28,845 | -15.5% | 44 | $1,006,000 | $991,343 | 6 | Sony Pictures Classics | - |
| 31 | 36 | +5 | The Class | $86,500 | $155,190 | +$68,690 | +79.4% | 25 | $121,000 | $314,334 | 7 | Sony Pictures Classics | - |
| 32 | 40 | +8 | Che: Part One/Che: Part Two | $70,200 | $79,027 | +$8,827 | +12.6% | 24 | $993,000 | $843,519 | 8 | IFC Films | - |
| 33 | 42 | +9 | Wendy and Lucy | $49,300 | $45,354 | -$3,946 | -8% | 13 | $255,000 | $251,210 | 8 | Oscilloscope | - |
| 34 | 52 | +18 | Vicky Cristina Barcelona | $20,200 | $20,425 | +$225 | +1.1% | 25 | $23,164,000 | $23,164,041 | 25 | - | - |
| 35 | 58 | +23 | Medicine for Melancholy | $14,700 | $12,625 | -$2,075 | -14.1% | 1 | $14,700 | $12,625 | 1 | IFC Films | - |
| 36 | 60 | +24 | Outlander | $8,100 | $9,270 | +$1,170 | +14.4% | 33 | $94,700 | $96,032 | 2 | Third Rail Releasing | - |
| 37 | 73 | +36 | Soul Men | $2,600 | $2,590 | -$10 | -0.4% | 11 | $12,081,000 | $12,081,447 | 13 | - | - |
| 38 | 78 | +40 | Killshot | $1,660 | $1,675 | +$15 | +0.9% | 5 | $16,700 | $17,007 | 2 | The Weinstein Company | - |
