| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Uncharted | $2,717,884 | - | 436 | - | $6,233 | $2,717,884 | - | Sony Pictures Releasing | - | false |
| 2 | 1 | Death on the Nile | $1,341,852 | -35.2% | 646 | +33 | $2,077 | $4,036,636 | 2 | Walt Disney Pictures | false | false |
| 3 | - | Ennio | $737,815 | - | 461 | - | $1,600 | $1,096,031 | 1 | Lucky Red | true | false |
| 4 | 2 | Marry Me | $290,608 | -31.3% | 337 | -61 | $862 | $935,219 | 2 | Universal Pictures | false | false |
| 5 | 5 | Spider-Man: No Way Home | $164,856 | -26.4% | 160 | -48 | $1,030 | $27,628,167 | 10 | Sony Pictures Releasing | false | false |
| 6 | 3 | The Wolf and the Lion | $163,250 | -37.1% | 268 | -101 | $609 | $2,381,328 | 5 | 01 Distribution | false | false |
| 7 | 4 | Nightmare Alley | $133,892 | -46.8% | 189 | -176 | $708 | $1,949,877 | 4 | Walt Disney Studios Motion Pictures | false | false |
| 8 | 6 | Me contro Te: Il film - Persi nel tempo | $65,980 | -24.3% | 154 | -48 | $428 | $3,887,847 | 8 | Warner Bros. | false | false |
| 9 | 7 | After Love | $62,927 | -19.1% | 60 | -2 | $1,048 | $173,736 | 2 | Teodora Film | false | false |
| 10 | - | Leonora addio | $55,724 | - | 94 | - | $592 | $55,724 | 1 | 01 Distribution | true | false |
| 11 | - | Una Femmina: The Code of Silence | $46,521 | - | 131 | - | $355 | $46,521 | 1 | Universal Pictures International (UPI) | true | false |
| 12 | 11 | Sing 2 | $45,287 | +4.7% | 64 | -19 | $707 | $2,623,905 | 9 | Universal Pictures International (UPI) | false | false |
| 13 | 10 | Small Body | $28,503 | -36.2% | 32 | -6 | $890 | $95,402 | 2 | Nefertiti Film | false | false |
| 14 | 8 | King Richard | $23,236 | -68.7% | 55 | -98 | $422 | $1,584,165 | 6 | Warner Bros. | false | false |
| 15 | 15 | The Good Boss | $20,934 | -12.8% | 26 | -7 | $805 | $642,706 | 9 | BIM Distribuzione | false | false |
| 16 | 23 | Encanto | $16,188 | +226.5% | 45 | - | $359 | $5,231,609 | 13 | Walt Disney Studios Motion Pictures | false | false |
| 17 | - | Giulia | $14,998 | - | 46 | - | $326 | $14,998 | 1 | Koch Media | true | false |
| 18 | 12 | Scream | $12,196 | -68.9% | 40 | -55 | $304 | $1,221,844 | 6 | Paramount Pictures | false | false |
| 19 | 9 | The Speech | $11,964 | -79.2% | 33 | -113 | $362 | $83,645 | 2 | - | false | false |
| 20 | 16 | Drive My Car | $11,746 | -40.7% | 14 | -8 | $839 | $303,318 | 22 | Tucker Film | false | false |
| 21 | 25 | Parallel Mothers | $2,252 | -21% | 3 | - | $750 | $2,754,979 | 17 | Warner Bros. | false | false |
| 22 | 24 | West Side Story | $1,594 | -59.6% | - | - | - | $606,885 | 9 | Walt Disney Studios Motion Pictures | false | false |
| 23 | 22 | The King's Man | $489 | -95.6% | - | - | - | $1,381,462 | 7 | Walt Disney Studios Motion Pictures | false | false |
| 24 | - | Ron's Gone Wrong | $426 | - | - | - | - | $1,101,694 | 18 | Walt Disney Studios Motion Pictures | false | false |
| 25 | 26 | The French Dispatch | $401 | -67.3% | - | - | - | $2,439,836 | 15 | Walt Disney Studios Motion Pictures | false | false |
