| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Spider-Man: No Way Home | $3,358,185 | -63.9% | 555 | +32 | $6,050 | $19,263,275 | 2 | Sony Pictures Releasing | false | false |
| 2 | 2 | House of Gucci | $918,977 | -46.4% | 507 | +36 | $1,812 | $3,499,554 | 2 | Paramount Pictures | false | false |
| 3 | 4 | Chi ha incastrato Babbo Natale? | $788,883 | +5% | 447 | +64 | $1,764 | $1,790,019 | 2 | - | false | false |
| 4 | 3 | Diabolik | $608,467 | -32.5% | 461 | +20 | $1,319 | $1,828,716 | 2 | 01 Distribution | false | false |
| 5 | - | Sing 2 | $602,715 | - | 532 | - | $1,132 | $904,107 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | - | 7 Women and a Murder | $305,158 | - | 387 | - | $788 | $305,158 | 1 | Warner Bros. | true | false |
| 7 | - | Supereroi | $210,642 | - | 400 | - | $526 | $210,642 | 1 | Medusa Distribuzione | true | false |
| 8 | - | West Side Story | $161,040 | - | 331 | - | $486 | $161,106 | 1 | Walt Disney Studios Motion Pictures | true | false |
| 9 | - | The Good Boss | $87,077 | - | 94 | - | $926 | $87,077 | 1 | BIM Distribuzione | true | false |
| 10 | 5 | Encanto | $86,850 | -65.1% | 195 | -99 | $445 | $5,062,813 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 11 | 6 | Mollo tutto e apro un chiringuito | $18,013 | -79.8% | 21 | -152 | $857 | $798,770 | 3 | Medusa Distribuzione | false | false |
| 12 | - | Clifford the Big Red Dog | $16,150 | - | 84 | - | $192 | $797,094 | 4 | Paramount Pictures | false | false |
| 13 | 8 | One Second | $15,893 | -42.9% | 34 | -7 | $467 | $54,960 | 2 | - | false | false |
| 14 | - | Lost Illusions | $11,438 | - | 7 | - | $1,634 | $14,019 | - | - | - | false |
| 15 | 7 | Compartment Number 6 | $11,003 | -71.3% | 16 | -37 | $687 | $300,675 | 4 | BIM Distribuzione | false | false |
| 16 | 9 | Nowhere Special | $8,423 | -69.5% | 24 | -43 | $350 | $154,379 | 23 | Lucky Red | false | false |
| 17 | 10 | Ghostbusters: Afterlife | $4,143 | -78.1% | 22 | -52 | $188 | $2,786,590 | 6 | Kino Swiat | false | false |
| 18 | 13 | The French Dispatch | $2,072 | -83.1% | 8 | -17 | $259 | $2,375,771 | 7 | Walt Disney Studios Motion Pictures | false | false |
| 19 | 16 | Freaks Out | $1,909 | -71.5% | 7 | -9 | $272 | $3,019,158 | 9 | 01 Distribution | false | false |
| 20 | 17 | The Rose Maker | $1,656 | -72.6% | 7 | -8 | $236 | $99,457 | 4 | - | false | false |
| 21 | 12 | Eternals | $695 | -94.9% | - | - | - | $9,765,790 | 8 | Walt Disney Studios Motion Pictures | false | false |
