Domestic 2021 Weekend 43
October 22-24, 2021
| TW | LW | Total | %± LW | Share | Releases | #1 Release | Gross | % of Total | Week | Distributor |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 9 | $41,065,338 | +15,661.5% | 43% | 3 | Dune: Part One | $41,011,174 | 99.9% | 1 | Warner Bros. |
| 2 | 1 | $14,724,505 | -70.7% | 15.4% | 3 | Halloween Kills | $14,450,215 | 98.1% | 2 | Universal Pictures |
| 3 | 2 | $12,202,368 | -48.7% | 12.8% | 1 | No Time to Die | $12,202,368 | 100% | 3 | Metro-Goldwyn-Mayer (MGM) |
| 4 | 5 | $9,610,907 | +77.8% | 10.1% | 3 | Ron's Gone Wrong | $7,300,225 | 76% | 1 | 20th Century Studios |
| 5 | 3 | $9,302,137 | -43.6% | 9.7% | 2 | Venom: Let There Be Carnage | $9,301,908 | 100% | 4 | Sony Pictures Releasing |
| 6 | 4 | $4,495,736 | -36.4% | 4.7% | 1 | The Addams Family 2 | $4,495,736 | 100% | 4 | United Artists Releasing |
| 7 | 6 | $2,081,316 | -39.3% | 2.2% | 2 | Shang-Chi and the Legend of the Ten Rings | $2,019,505 | 97% | 8 | Walt Disney Studios Motion Pictures |
| 8 | 18 | $1,358,364 | +5,948.2% | 1.4% | 2 | The French Dispatch | $1,348,804 | 99.3% | 1 | Searchlight Pictures |
| 9 | 7 | $159,075 | -70.7% | 0.2% | 1 | Lamb | $159,075 | 100% | 3 | A24 |
| 10 | 8 | $134,736 | -64.7% | 0.1% | 1 | The Rescue | $134,736 | 100% | 3 | Greenwich Entertainment |
| 12 | 10 | $41,099 | -54.4% | <0.1% | 1 | Titane | $41,099 | 100% | 4 | Neon |
| 13 | 14 | $32,880 | -41.5% | <0.1% | 2 | Mass | $23,794 | 72.4% | 3 | Bleecker Street Media |
| 14 | 13 | $25,362 | -55.5% | <0.1% | 2 | Bergman Island | $23,776 | 93.7% | 2 | IFC Films |
| 15 | 11 | $17,567 | -70.6% | <0.1% | 1 | After We Fell | $17,567 | 100% | 7 | Vertical Entertainment |
| 16 | 15 | $15,556 | -65.8% | <0.1% | 2 | The Alpinist | $9,023 | 58% | 7 | Roadside Attractions |
| 17 | 20 | $10,784 | +62.1% | <0.1% | 3 | Luzzu | $5,767 | 53.5% | 2 | Kino Lorber |
| 21 | 21 | $5,686 | +57.2% | <0.1% | 3 | Golden Voices | $5,558 | 97.7% | 3 | Music Box Films |
| 22 | 22 | $4,988 | +58% | <0.1% | 1 | Minyan | $4,988 | 100% | 1 | Strand Releasing |
| 23 | 12 | $3,954 | -93.1% | <0.1% | 1 | Monster Family 2 | $3,954 | 100% | 2 | Viva Pictures |
| 24 | 17 | $3,870 | -84.5% | <0.1% | 1 | My Country, My Parents | $3,870 | 100% | 3 | CMC Pictures |
| 25 | 26 | $1,242 | -20.5% | <0.1% | 1 | Old Henry | $1,242 | 100% | 4 | Shout! Factory |
| 26 | 27 | $1,050 | -25.1% | <0.1% | 2 | The Lost Leonardo | $1,009 | 96.1% | 11 | Sony Pictures Classics |
| 27 | 24 | $996 | -45.4% | <0.1% | 1 | Tango Shalom | $996 | 100% | 8 | Vision Films |
| 28 | 23 | $505 | -74.2% | <0.1% | 1 | Azor | $505 | 100% | 7 | MUBI |
| 29 | 25 | $129 | -92.3% | <0.1% | 1 | Breathless 2021 Re-release | $129 | 100% | 5 | Rialto Pictures |
