| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Dune | $2,504,453 | - | 452 | - | $5,540 | $2,505,378 | 1 | Warner Bros. | true | false |
| 2 | 1 | Shang-Chi and the Legend of the Ten Rings | $476,770 | -41.7% | 311 | -92 | $1,533 | $3,937,493 | 3 | Walt Disney Studios Motion Pictures | false | false |
| 3 | 2 | The King of Laughter | $350,668 | -5.4% | 320 | +43 | $1,095 | $873,905 | 2 | 01 Distribution | false | false |
| 4 | 3 | Like a Cat on a Highway 2 | $282,536 | -22.4% | 280 | -101 | $1,009 | $3,096,895 | 4 | - | false | false |
| 5 | - | Around the World in 80 Days 2021 Re-release | $270,294 | - | 294 | - | $919 | - | 2 | BIM Distribuzione | false | false |
| 6 | 4 | Me contro te - Il mistero della scuola incantata | $158,686 | -33.2% | 239 | -78 | $663 | $5,810,045 | 5 | Warner Bros. | false | false |
| 7 | - | Still Out of My League | $153,930 | - | 331 | - | $465 | $166,130 | 1 | Paramount Pictures | true | false |
| 8 | 5 | F9: The Fast Saga | $128,531 | -35.5% | 143 | -70 | $898 | $5,578,407 | 5 | Universal Pictures International (UPI) | false | false |
| 9 | - | Supernova | $105,107 | - | 111 | - | $946 | $131,095 | 1 | Lucky Red | true | false |
| 10 | - | Il silenzio grande | $63,614 | - | 109 | - | $583 | $63,614 | 1 | - | true | false |
| 11 | 11 | Welcome Venice | $48,558 | -5.3% | 38 | -27 | $1,277 | $140,618 | 2 | Lucky Red | false | false |
| 12 | 7 | Stillwater | $39,316 | -69.3% | 120 | -181 | $327 | $209,210 | 2 | Universal Pictures | false | false |
| 13 | 8 | Malignant | $38,055 | -69.2% | 63 | -160 | $604 | $493,339 | 3 | Warner Bros. | false | false |
| 14 | 9 | The Card Counter | $36,942 | -66.5% | 85 | -150 | $434 | $432,855 | 3 | STX International | false | false |
| 15 | - | Rosa's Wedding | $26,382 | - | 36 | - | $732 | $42,386 | 1 | Officine UBU | true | false |
| 16 | 16 | Free Guy | $24,529 | +10.6% | 42 | - | $584 | $1,003,942 | 6 | Walt Disney Studios Motion Pictures | false | false |
| 17 | 13 | Mondocane | $10,224 | -59% | 15 | -101 | $681 | $125,835 | 3 | 01 Distribution | false | false |
| 18 | - | Spin Time, che fatica la democrazia! | $9,611 | - | 17 | - | $565 | $9,611 | 1 | - | true | false |
| 19 | - | Blue Bayou | $7,429 | - | 56 | - | $132 | $7,429 | 1 | Universal Pictures International (UPI) | true | false |
| 20 | 17 | Wheel of Fortune and Fantasy | $6,902 | -42.6% | 10 | -15 | $690 | $102,212 | 12 | Tucker Film | false | false |
| 21 | 15 | Jungle Cruise | $2,772 | -88.3% | - | - | - | $1,961,483 | 8 | Walt Disney Studios Motion Pictures | false | false |
| 22 | 23 | Nomadland | $1,860 | -46.4% | - | - | - | $2,116,255 | 21 | Walt Disney Pictures | false | false |
