| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Solo: A Star Wars Story | $1,721,414 | - | 837 | - | $2,056 | $2,174,511 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Deadpool 2 | $1,168,948 | -62.6% | 628 | -81 | $1,861 | $6,553,264 | 2 | 20th Century Fox International | false | false |
| 3 | 2 | Dogman | $636,519 | -4.5% | 408 | +31 | $1,560 | $1,711,366 | 2 | 01 Distribution | false | false |
| 4 | 3 | Loro 2 | $224,459 | -63.2% | 351 | -192 | $639 | $2,745,270 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Avengers: Infinity War | $208,209 | -61.2% | 237 | -165 | $878 | $21,480,938 | 5 | Walt Disney Pictures | false | false |
| 6 | - | Hotel Gagarin | $146,966 | - | 165 | - | $890 | $146,966 | 1 | Altre Storie | true | false |
| 7 | 5 | Show Dogs | $146,196 | -57.7% | 276 | -68 | $529 | $1,404,939 | 3 | Eagle Pictures | false | false |
| 8 | - | Nobili bugie | $115,769 | - | 33 | - | $3,508 | $115,769 | 1 | Genoma Films | true | false |
| 9 | 10 | Lost in Paris | $74,329 | -24.9% | 63 | +14 | $1,179 | $196,339 | 2 | Academy 2 | false | false |
| 10 | 6 | Arrivano i prof | $70,206 | -58.7% | 108 | -102 | $650 | $2,308,678 | 4 | 01 Distribution | false | false |
| 11 | 8 | The Full House | $45,504 | -62.2% | 113 | -95 | $402 | $204,611 | 2 | Notorious Pictures | false | false |
| 12 | 7 | Loro 1 | $37,565 | -75.6% | 82 | -117 | $458 | $4,740,179 | 5 | Universal Pictures International (UPI) | false | false |
| 13 | - | Montparnasse Bienvenüe | $36,645 | - | 37 | - | $990 | $36,645 | 1 | Parthenos | true | false |
| 14 | - | Mektoub, My Love: Canto Uno | $35,949 | - | 73 | - | $492 | $35,949 | 1 | - | true | false |
| 15 | 11 | Loving Pablo | $31,824 | -64.3% | 47 | -703 | $677 | $4,023,182 | 6 | Notorious Pictures | false | false |
| 16 | 9 | Wonders of the Sea | $29,427 | -74.2% | 160 | -91 | $183 | $178,635 | 2 | M2 Pictures | false | false |
| 17 | 12 | Tonno spiaggiato | $19,263 | -70.8% | 44 | -98 | $437 | $443,769 | 3 | - | false | false |
| 18 | - | Darkest Hour | $18,857 | - | 37 | - | $509 | $5,070,459 | 19 | Universal Pictures International (UPI) | false | false |
| 19 | 16 | The House by the Sea | $18,095 | -51.3% | 19 | -11 | $952 | $574,986 | 7 | Parthenos | false | false |
| 20 | 13 | Game Night | $17,550 | -62.4% | 23 | -42 | $763 | $1,076,185 | 4 | Warner Bros. | false | false |
| 21 | 14 | Blockers | $4,605 | -90% | 4 | -101 | $1,151 | $70,851 | 2 | Universal Pictures International (UPI) | false | false |
| 22 | 23 | Wonder | $3,590 | +164% | 4 | +2 | $897 | $14,488,373 | 23 | 01 Distribution | false | false |
| 23 | 22 | Call Me by Your Name | $1,283 | -37% | 2 | - | $641 | $3,909,926 | 18 | Sony Pictures Releasing | false | false |
| 24 | 21 | Sherlock Gnomes | $892 | -73.3% | 8 | -7 | $111 | $920,901 | 7 | Paramount Pictures International | false | false |
| 25 | 24 | Peter Rabbit | $598 | -48% | 3 | -3 | $199 | $3,150,214 | 10 | Sony Pictures Releasing | false | false |
| 26 | 26 | Based on a True Story | $468 | +115.7% | 3 | +2 | $156 | $585,906 | 13 | - | false | false |
| 27 | 25 | Coco | $434 | +10.4% | - | - | - | $14,405,491 | 22 | Walt Disney Pictures | false | false |
