| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avengers: Infinity War | $8,647,448 | -65.9% | - | - | - | $48,565,249 | 2 | Walt Disney Pictures | false | false |
| 2 | - | The Strangers: Prey at Night | $725,427 | - | - | - | - | $725,427 | 1 | Diamond Films | true | false |
| 3 | - | 24 Hours to Live | $385,545 | - | - | - | - | $385,545 | 1 | - | true | false |
| 4 | 2 | Rampage | $356,487 | -43.4% | - | - | - | $11,815,436 | 4 | Warner Bros. | false | false |
| 5 | - | Paul, Apostle of Christ | $266,198 | - | - | - | - | $266,198 | 1 | Cinépolis Distribución | true | false |
| 6 | 3 | Truth or Dare | $211,394 | -50.6% | 395 | -269 | $535 | $2,972,617 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | - | Isle of Dogs | $199,187 | - | 85 | - | $2,343 | $199,187 | 1 | 20th Century Fox International | true | false |
| 8 | 5 | Gnome Alone | $171,238 | +19.4% | - | - | - | $839,067 | 3 | - | false | false |
| 9 | 4 | A Quiet Place | $136,048 | -46.8% | 275 | -261 | $494 | $7,531,110 | 5 | Paramount Pictures International | false | false |
| 10 | - | Game Night | $95,478 | - | - | - | - | $1,403,115 | 5 | Warner Bros. | false | false |
| 11 | 6 | Love, Simon | $75,765 | -43.2% | 153 | -199 | $495 | $2,606,913 | 4 | 20th Century Fox International | false | false |
| 12 | - | Lady Bird | $21,679 | - | 60 | - | $361 | $426,852 | 12 | Universal Pictures International (UPI) | false | false |
| 13 | 10 | Sherlock Gnomes | $15,391 | -62.5% | 55 | -208 | $279 | $2,639,618 | 6 | Paramount Pictures International | false | false |
| 14 | 16 | 12 Strong | $8,748 | +440.3% | 13 | +7 | $672 | $414,470 | 9 | Sun Distribution | false | false |
| 15 | - | Earth: One Amazing Day | $8,600 | - | 11 | - | $781 | $8,600 | 1 | Universal Pictures International (UPI) | true | false |
| 16 | 11 | 7 Days in Entebbe | $8,033 | -32% | 10 | -3 | $803 | $304,572 | 4 | Sun Distribution | false | false |
| 17 | 12 | Peter Rabbit | $4,579 | -52.4% | 12 | -29 | $381 | $4,399,076 | 8 | Sony Pictures Releasing | false | false |
| 18 | 14 | A Wrinkle in Time | $2,947 | -21% | - | - | - | $2,369,275 | 6 | Walt Disney Pictures | false | false |
| 19 | 19 | Phantom Thread | $2,631 | +826.4% | 10 | +6 | $263 | $376,659 | 11 | Universal Pictures International (UPI) | false | false |
| 20 | 18 | Darkest Hour | $1,004 | -30.5% | 1 | - | $1,004 | $620,987 | 16 | Universal Pictures International (UPI) | false | false |
| 21 | - | Mary Magdalene | $984 | - | 4 | - | $246 | $615,341 | 7 | Universal Pictures International (UPI) | false | false |
| 22 | 13 | Black Panther | $850 | -80.4% | - | - | - | $28,322,788 | 12 | Walt Disney Pictures | false | false |
| 23 | 15 | Pacific Rim: Uprising | $478 | -73.6% | 3 | -13 | $159 | $11,821,225 | 7 | Universal Pictures International (UPI) | false | false |
| 24 | 17 | Based on a True Story | $394 | -75.5% | 1 | -1 | $394 | $326,971 | 8 | - | false | false |
| 25 | 21 | Human Flow | $380 | +427.8% | 3 | +1 | $126 | $7,121 | 7 | - | false | false |
