| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | Me Before You | $2,073,505 | -20.3% | 529 | +84 | $3,919 | $6,386,559 | 2 | Warner Bros. | false | false |
| 2 | 2 | Teenage Mutant Ninja Turtles: Out of the Shadows | $1,199,253 | -76.4% | 515 | +2 | $2,328 | $6,848,319 | 2 | Paramount Pictures International | false | false |
| 3 | 4 | Alice Through the Looking Glass | $1,187,909 | -39.5% | 572 | -11 | $2,076 | $11,846,995 | 3 | Walt Disney Pictures | false | false |
| 4 | 1 | Warcraft | $1,038,519 | -80.3% | 509 | +9 | $2,040 | $7,162,822 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | 5 | X-Men: Apocalypse | $1,003,344 | -44.7% | 456 | -53 | $2,200 | $24,342,070 | 4 | 20th Century Fox International | false | false |
| 6 | 6 | The Nice Guys | $915,175 | -37.3% | 510 | +26 | $1,794 | $3,184,200 | 2 | Icon Film Distribution | false | false |
| 7 | - | The Boss | $848,126 | - | 439 | - | $1,931 | $848,126 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | 7 | The Angry Birds Movie | $825,980 | -33.1% | 543 | -3 | $1,521 | $13,449,305 | 5 | Sony Pictures Releasing | false | false |
| 9 | - | Mother's Day | $598,340 | - | 401 | - | $1,492 | $598,340 | 1 | Lionsgate Films | true | false |
| 10 | 8 | The Jungle Book | $588,108 | -29% | 439 | -52 | $1,339 | $64,338,640 | 9 | Walt Disney Pictures | false | false |
| 11 | 9 | Money Monster | $255,765 | -51.4% | 307 | -82 | $833 | $3,405,418 | 3 | Sony Pictures Releasing | false | false |
| 12 | 12 | Love & Friendship | $242,878 | -30.2% | 169 | +51 | $1,437 | $1,672,076 | 3 | Lionsgate Films | false | false |
| 13 | 11 | Captain America: Civil War | $210,344 | -43.6% | 230 | -57 | $914 | $52,444,210 | 7 | Walt Disney Pictures | false | false |
| 14 | - | When Marnie Was There | $141,697 | - | 53 | - | $2,673 | $141,697 | 1 | StudioCanal UK | true | false |
| 15 | 13 | Zootopia | $125,281 | -54.8% | 260 | -105 | $481 | $33,601,540 | 12 | Walt Disney Pictures | false | false |
| 16 | - | Where to Invade Next | $121,948 | - | 127 | - | $960 | $121,948 | 1 | Periscoop Film | true | false |
| 17 | - | Embrace of the Serpent | $59,026 | - | 21 | - | $2,810 | $59,026 | 1 | Peccadillo Pictures | true | false |
| 18 | - | Te3n | $51,208 | - | 30 | - | $1,706 | $51,208 | 1 | Reliance Big Pictures | true | false |
| 19 | - | Learning to Drive | $45,596 | - | 79 | - | $577 | $45,596 | 1 | Vertigo Films | true | false |
| 20 | - | Miracles from Heaven | $29,123 | - | 110 | - | $264 | $29,123 | 1 | Sony Pictures Releasing | true | false |
| 21 | 17 | Florence Foster Jenkins | $25,917 | -36% | 73 | +3 | $355 | $4,346,519 | 6 | 20th Century Fox International | false | false |
| 22 | 19 | Our Kind of Traitor | $21,777 | -33.4% | 51 | +1 | $427 | $1,615,534 | 5 | StudioCanal | false | false |
| 23 | - | Fire at Sea | $18,705 | - | 15 | - | $1,247 | $18,705 | 1 | Artificial Eye | true | false |
| 24 | 20 | Eye in the Sky | $13,662 | -38.9% | 38 | -33 | $359 | $7,123,796 | 9 | Entertainment One | false | false |
| 25 | - | Dulla Bhatti Wala | $7,876 | - | 7 | - | $1,125 | $7,876 | 1 | - | true | false |
| 26 | 18 | Thomas & Friends: The Great Race | $6,515 | -82% | 21 | -116 | $310 | $404,411 | 4 | National Amusements | false | false |
| 27 | 37 | The Man Who Knew Infinity | $5,923 | +1,689.4% | 5 | +4 | $1,184 | $756,479 | 10 | Warner Bros. | false | false |
| 28 | 23 | A Hologram for the King | $5,758 | -66.7% | 33 | -3 | $174 | $659,367 | 4 | Icon Film Distribution | false | false |
| 29 | 33 | Bobby | $4,622 | +219.9% | 2 | +1 | $2,311 | $12,931 | 3 | Entertainment One | false | false |
| 30 | - | Once Upon a Time in Amritsar | $3,701 | - | 6 | - | $616 | $3,701 | 1 | - | true | false |
| 31 | - | I Saw the Light | $3,007 | - | 6 | - | $501 | $85,772 | 6 | Sony Pictures Releasing | false | false |
| 32 | - | The Stanford Prison Experiment | $2,553 | - | 4 | - | $638 | $2,553 | 1 | Munro Films | true | false |
| 33 | 22 | Versus: The Life and Films of Ken Loach | $2,199 | -87.8% | 10 | -18 | $219 | $37,024 | 2 | Periscoop Film | false | false |
| 34 | 32 | Golden Years | $1,954 | +13.8% | 4 | - | $488 | $89,159 | 7 | N/A | false | false |
| 35 | 27 | Eddie the Eagle | $1,613 | -76.6% | 8 | -1 | $201 | $12,303,212 | 11 | Lionsgate Films | false | false |
| 36 | 30 | Departure | $983 | -71.5% | 4 | -3 | $245 | $24,474 | 4 | Peccadillo Pictures | false | false |
| 37 | 34 | The Take | $247 | -60.2% | 4 | -1 | $61 | $2,838,767 | 8 | StudioCanal | false | false |
| 38 | 35 | High-Rise | $111 | -81.4% | 1 | -1 | $111 | $2,803,896 | 13 | StudioCanal | false | false |
