| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Maze Runner: The Scorch Trials | $1,181,924 | - | 81 | - | $14,591 | $1,181,924 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Fantastic Four | $364,204 | -40.9% | 47 | -5 | $7,749 | $7,482,258 | 5 | 20th Century Fox International | false | false |
| 3 | 3 | Pixels | $311,088 | -17.1% | 52 | -3 | $5,982 | $9,403,664 | 9 | Sony Pictures Releasing | false | false |
| 4 | 2 | Hitman: Agent 47 | $233,091 | -44.7% | 44 | -3 | $5,297 | $1,957,126 | 3 | 20th Century Fox International | false | false |
| 5 | 4 | Minions | $204,312 | -43.2% | 40 | -4 | $5,107 | $26,699,325 | 11 | United International Pictures | false | false |
| 6 | - | Magic Mike XXL | $130,309 | - | 34 | - | $3,832 | $130,309 | 1 | Warner Bros. | true | false |
| 7 | 7 | Inside Out | $119,604 | -27.2% | 36 | +2 | $3,322 | $25,119,711 | 14 | Walt Disney Pictures | false | false |
| 8 | 5 | The Man from U.N.C.L.E. | $118,648 | -61.5% | 36 | -9 | $3,295 | $654,973 | 2 | Warner Bros. | false | false |
| 9 | - | Jessabelle | $91,310 | - | 19 | - | $4,805 | $91,310 | 1 | - | true | false |
| 10 | 10 | Ant-Man | $72,777 | -37.3% | 24 | -3 | $3,032 | $6,580,533 | 10 | Walt Disney Pictures | false | false |
| 11 | 11 | Vacation | $70,129 | -34.6% | 11 | - | $6,375 | $2,249,235 | 8 | Warner Bros. | false | false |
| 12 | 8 | Ricki and the Flash | $63,206 | -58.1% | 15 | -21 | $4,213 | $311,719 | 2 | Sony Pictures Releasing | false | false |
| 13 | 9 | Mission: Impossible - Rogue Nation | $59,097 | -49.7% | 13 | -5 | $4,545 | $5,318,725 | 8 | United International Pictures | false | false |
| 14 | 6 | Sinister 2 | $56,508 | -67.6% | 14 | -14 | $4,036 | $730,270 | 3 | - | false | false |
| 15 | 12 | All Creatures Big And Small 2015 Re-release | $52,597 | -31.2% | 20 | +1 | $2,629 | $1,993,714 | 8 | N/A | false | false |
| 16 | 14 | Insidious: Chapter 3 | $27,013 | -28.8% | 11 | -2 | $2,455 | $2,060,094 | 13 | Sony Pictures Releasing | false | false |
| 17 | 15 | Avengers: Age of Ultron | $24,035 | -11.5% | 9 | -1 | $2,670 | $18,454,993 | 21 | Walt Disney Pictures | false | false |
| 18 | 16 | 1,000 Times Good Night | $23,721 | -4.8% | 2 | -1 | $11,860 | $331,242 | 4 | N/A | false | false |
| 19 | - | Coming Home | $19,684 | - | 3 | - | $6,561 | $19,684 | 1 | Sony Pictures Releasing | true | false |
| 20 | 19 | Before I Go to Sleep | $17,280 | -20.4% | 1 | -1 | $17,280 | $458,915 | 7 | N/A | false | false |
| 21 | 18 | Home | $17,188 | -20.9% | 12 | - | $1,432 | $6,198,175 | 19 | 20th Century Fox International | false | false |
| 22 | 17 | A Mouse Tale | $14,570 | -35.3% | 5 | -5 | $2,914 | $115,608 | 3 | N/A | false | false |
| 23 | 25 | Paul Blart: Mall Cop 2 | $10,214 | +37.9% | 10 | +2 | $1,021 | $5,179,322 | 23 | Sony Pictures Releasing | false | false |
| 24 | 13 | Pitch Perfect 2 | $8,112 | -83.8% | 4 | -13 | $2,028 | $317,629 | 3 | United International Pictures | false | false |
| 25 | 21 | Unfriended | $6,650 | -60.7% | 3 | -4 | $2,216 | $594,543 | 5 | United International Pictures | false | false |
| 26 | - | Neighbors | $2,228 | - | 1 | - | $2,228 | $411,660 | 54 | United International Pictures | false | false |
| 27 | 27 | Thunder and the House of Magic | $2,034 | -68.2% | 2 | -1 | $1,017 | $533,101 | 6 | - | false | false |
| 28 | - | Alexander and the Terrible, Horrible, No Good, Very Bad Day | $1,898 | - | 2 | - | $949 | $1,770,303 | 50 | Walt Disney Pictures | false | false |
| 29 | 30 | Annie | $982 | +254.5% | 2 | +1 | $491 | $1,982,251 | 29 | Sony Pictures Releasing | false | false |
| 30 | - | Taken 3 | $807 | - | 2 | - | $403 | $2,874,221 | 29 | 20th Century Fox International | false | false |
| 31 | - | Night at the Museum: Secret of the Tomb | $660 | - | 1 | - | $660 | $5,487,017 | 35 | 20th Century Fox International | false | false |
| 32 | - | Big Hero 6 | $653 | - | 3 | - | $217 | $2,470,582 | 41 | Walt Disney Pictures | false | false |
| 33 | - | Kingsman: The Secret Service | $300 | - | 1 | - | $300 | $1,824,852 | 23 | 20th Century Fox International | false | false |
| 34 | - | Cinderella | $157 | - | 2 | - | $78 | $8,187,965 | 28 | Walt Disney Pictures | false | false |
