| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | American Ultra | $23,567 | - | 10 | - | $2,356 | $23,720 | 1 | N/A | true | false |
| 2 | 1 | Inside Out | $17,815 | -30.6% | 8 | -3 | $2,226 | $302,838 | 5 | Walt Disney Pictures | false | false |
| 3 | 2 | Vacation | $17,454 | -29.1% | 10 | +2 | $1,745 | $57,447 | 2 | Warner Bros. | false | false |
| 4 | - | Knock Knock | $12,056 | - | 8 | - | $1,507 | $12,134 | 1 | ACME | true | false |
| 5 | 4 | The Man from U.N.C.L.E. | $10,666 | -36.7% | 6 | -5 | $1,777 | $79,244 | 3 | Warner Bros. | false | false |
| 6 | 5 | Hitman: Agent 47 | $7,375 | -35% | 8 | -1 | $921 | $58,730 | 3 | 20th Century Fox International | false | false |
| 7 | 6 | Southpaw | $7,375 | -24.1% | 6 | +1 | $1,229 | $85,276 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 8 | Mission: Impossible - Rogue Nation | $5,098 | +4.8% | 5 | - | $1,019 | $215,854 | 6 | N/A | false | false |
| 9 | - | Trainwreck | $4,369 | - | 5 | - | $873 | $76,684 | 5 | United International Pictures | false | false |
| 10 | 11 | Pixels | $285 | -29.1% | 2 | +1 | $142 | $54,279 | 7 | Sony Pictures Releasing | false | false |
