| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 4 | The Descendants | $2,522,874 | +6.5% | 217 | +28 | $11,626 | $6,322,888 | 2 | 20th Century Fox International | false | false |
| 2 | - | Journey 2: The Mysterious Island | $2,002,193 | - | 351 | - | $5,704 | $2,002,193 | 1 | Warner Bros. | true | false |
| 3 | 1 | Sherlock Holmes: A Game of Shadows | $1,951,858 | -42.2% | 362 | -26 | $5,391 | $16,451,310 | 3 | Roadshow Films | false | false |
| 4 | 3 | The Muppets | $1,741,721 | -26.8% | 268 | -32 | $6,498 | $5,958,104 | 2 | Walt Disney Pictures | false | false |
| 5 | 2 | The Girl with the Dragon Tattoo | $1,517,338 | -37.1% | 257 | +5 | $5,904 | $5,076,259 | 2 | Sony Pictures Releasing | false | false |
| 6 | - | Tinker Tailor Soldier Spy | $1,492,336 | - | 144 | - | $10,363 | $1,583,723 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | 5 | Alvin and the Chipmunks: Chipwrecked | $1,325,474 | -40.5% | 269 | -1 | $4,927 | $17,467,946 | 4 | 20th Century Fox International | false | false |
| 8 | 6 | Hugo | $1,230,008 | -29.9% | 368 | -28 | $3,342 | $4,066,510 | 2 | Paramount Pictures International | false | false |
| 9 | - | The Darkest Hour | $658,043 | - | 156 | - | $4,218 | $677,742 | 1 | 20th Century Fox International | true | false |
| 10 | 10 | The Iron Lady | $508,182 | -33.2% | 136 | +9 | $3,736 | $7,905,938 | 4 | Icon Film Distribution | false | false |
| 11 | 7 | The Adventures of Tintin | $492,137 | -50.1% | 293 | -132 | $1,679 | $14,863,021 | 4 | Paramount Pictures International | false | false |
| 12 | 8 | War Horse | $464,629 | -46.2% | 190 | -38 | $2,445 | $9,747,848 | 4 | Walt Disney Pictures | false | false |
| 13 | 9 | Tower Heist | $378,434 | -50.8% | 149 | -44 | $2,539 | $9,984,783 | 4 | Universal Pictures International (UPI) | false | false |
| 14 | 11 | Happy Feet Two | $374,680 | -44.4% | 218 | -87 | $1,718 | $10,369,916 | 4 | Roadshow Films | false | false |
| 15 | 13 | Mission: Impossible - Ghost Protocol | $286,173 | -52.4% | 144 | -57 | $1,987 | $17,832,765 | 6 | Paramount Pictures International | false | false |
| 16 | 12 | We Bought a Zoo | $283,639 | -55.8% | 151 | -75 | $1,878 | $7,755,984 | 4 | 20th Century Fox International | false | false |
| 17 | - | Young Adult | $247,919 | - | 57 | - | $4,349 | $247,919 | 1 | Paramount Pictures International | true | false |
| 18 | 15 | The Women on the 6th Floor | $127,261 | +21.1% | 25 | -2 | $5,090 | $1,660,005 | 7 | Palace Films | false | false |
| 19 | 14 | Puss in Boots | $120,634 | -42.3% | 80 | -27 | $1,507 | $15,642,773 | 7 | Paramount Pictures International | false | false |
| 20 | - | Faust | $88,701 | - | 26 | - | $3,411 | $88,701 | 1 | Sharmill Films | true | false |
