| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Transformers: Dark of the Moon | $584,593 | - | 103 | - | $5,675 | $902,764 | 1 | N/A | true | false |
| 2 | 1 | Rise of the Planet of the Apes | $226,059 | -28.4% | 70 | -3 | $3,229 | $1,404,838 | 3 | 20th Century Fox International | false | false |
| 3 | 2 | Mr. Popper's Penguins | $174,574 | -27.8% | 53 | -4 | $3,293 | $2,201,098 | 5 | 20th Century Fox International | false | false |
| 4 | 3 | Bad Teacher | $169,985 | -21% | 51 | +1 | $3,333 | $554,342 | 2 | Sony Pictures Releasing | false | false |
| 5 | 4 | Sanctum | $64,806 | -55.3% | 27 | -15 | $2,400 | $302,243 | 2 | N/A | false | false |
| 6 | 8 | The Rumble of the Stones | $51,070 | +2.6% | 24 | - | $2,127 | $250,123 | 3 | N/A | false | false |
| 7 | - | Something Borrowed | $49,579 | - | 15 | - | $3,305 | $78,767 | 1 | N/A | true | false |
| 8 | 7 | Abduction | $38,365 | -42% | 25 | -3 | $1,534 | $537,649 | 4 | N/A | false | false |
| 9 | 5 | Fright Night | $35,527 | -61% | 30 | -22 | $1,184 | $531,464 | 3 | Walt Disney Pictures | false | false |
| 10 | 6 | Friends with Benefits | $27,925 | -59.5% | 22 | -12 | $1,269 | $1,492,452 | 6 | Sony Pictures Releasing | false | false |
| 11 | 9 | Er Conde Jones | $20,822 | -48.8% | 18 | -14 | $1,156 | $3,542,084 | 8 | N/A | false | false |
| 12 | 11 | Garfield's Pet Force | $15,785 | -20.4% | 11 | -4 | $1,435 | $414,403 | 5 | N/A | false | false |
| 13 | 12 | Hoodwinked Too! Hood vs. Evil | $7,747 | -48.4% | 16 | -2 | $484 | $59,737 | 3 | N/A | false | false |
| 14 | 10 | Cars 2 | $4,975 | -76.1% | 11 | -12 | $452 | $4,567,183 | 9 | Walt Disney Pictures | false | false |
| 15 | 13 | Green Lantern | $1,996 | -80% | 5 | -9 | $399 | $2,663,058 | 7 | Warner Bros. | false | false |
| 16 | 14 | Insidious | $1,392 | -83.3% | 3 | -6 | $464 | $324,804 | 6 | N/A | false | false |
| 17 | 16 | Chinese Take-Away | $1,115 | -67.3% | 2 | +1 | $557 | $58,335 | 4 | Walt Disney Pictures | false | false |
| 18 | 19 | Crazy, Stupid, Love. | $935 | -12.1% | 1 | - | $935 | $1,061,554 | 9 | Warner Bros. | false | false |
| 19 | 17 | Saluda al diablo de mi parte | $815 | -75.1% | 3 | -5 | $271 | $299,390 | 6 | N/A | false | false |
| 20 | 15 | The Smurfs | $786 | -80% | 6 | -5 | $131 | $7,756,427 | 11 | Sony Pictures Releasing | false | false |
| 21 | 18 | The Dilemma | $668 | -58.7% | 2 | -3 | $334 | $256,873 | 5 | United International Pictures | false | false |
| 22 | 21 | Igor | $140 | -50% | 2 | - | $70 | $56,582 | 6 | N/A | false | false |
