| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Mr. Popper's Penguins | $328,195 | -4% | 59 | -3 | $5,562 | $926,007 | 2 | 20th Century Fox International | false | false |
| 2 | 2 | Green Lantern | $187,944 | -22.9% | 64 | +1 | $2,936 | $2,465,652 | 4 | Warner Bros. | false | false |
| 3 | 4 | Friends with Benefits | $171,993 | -21.1% | 47 | -3 | $3,659 | $1,055,397 | 3 | Sony Pictures Releasing | false | false |
| 4 | - | Abduction | $143,367 | - | 30 | - | $4,778 | $143,367 | 1 | N/A | true | false |
| 5 | 3 | Er Conde Jones | $135,108 | -38.5% | 45 | -4 | $3,002 | $3,227,176 | 5 | N/A | false | false |
| 6 | 5 | Cars 2 | $75,988 | -35.8% | 47 | -10 | $1,616 | $4,446,573 | 6 | Walt Disney Pictures | false | false |
| 7 | 6 | Garfield's Pet Force | $69,162 | -28.6% | 30 | -1 | $2,305 | $268,692 | 2 | N/A | false | false |
| 8 | 7 | The Dilemma | $59,620 | -22.6% | 31 | - | $1,923 | $193,477 | 2 | United International Pictures | false | false |
| 9 | 9 | Saluda al diablo de mi parte | $40,269 | -8% | 17 | -1 | $2,368 | $235,671 | 3 | N/A | false | false |
| 10 | 10 | Insidious | $38,776 | -10.4% | 19 | +1 | $2,040 | $248,398 | 3 | N/A | false | false |
| 11 | 8 | The Smurfs | $35,914 | -42.9% | 30 | -21 | $1,197 | $7,714,699 | 8 | Sony Pictures Releasing | false | false |
| 12 | 11 | Limitless | $15,228 | -45.2% | 8 | -6 | $1,903 | $613,517 | 5 | N/A | false | false |
| 13 | 13 | Horrible Bosses | $14,095 | -26.6% | 7 | +1 | $2,013 | $1,351,358 | 8 | Warner Bros. | false | false |
| 14 | - | Chinese Take-Away | $12,906 | - | 3 | - | $4,302 | $17,806 | 1 | Walt Disney Pictures | true | false |
| 15 | 12 | Crazy, Stupid, Love. | $11,019 | -45.9% | 10 | -5 | $1,101 | $1,039,002 | 6 | Warner Bros. | false | false |
| 16 | 14 | Igor | $3,420 | -22% | 10 | -6 | $342 | $50,689 | 3 | N/A | false | false |
| 17 | 18 | You Will Meet a Tall Dark Stranger | $1,709 | -31.7% | 1 | - | $1,709 | $93,803 | 7 | N/A | false | false |
| 18 | 17 | Paul | $1,325 | -47.9% | 7 | +2 | $189 | $172,466 | 4 | United International Pictures | false | false |
| 19 | 19 | Season of the Witch | $1,169 | -40.6% | 2 | - | $584 | $762,058 | 7 | N/A | false | false |
| 20 | 16 | Zookeeper | $772 | -69.8% | 2 | -5 | $386 | $4,016,988 | 10 | Sony Pictures Releasing | false | false |
| 21 | 20 | The Beaver | $746 | +7.6% | 1 | -1 | $746 | $183,334 | 7 | N/A | false | false |
| 22 | 15 | Solitary Man | $404 | -85.1% | 2 | -3 | $202 | $89,653 | 5 | N/A | false | false |
| 23 | 21 | Skyline | $70 | -84.4% | 1 | -1 | $70 | $149,551 | 6 | N/A | false | false |
