| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 4 | Crazy, Stupid, Love. | $6,195 | +109.8% | 4 | - | $1,548 | $16,790 | 3 | Warner Bros. | false | false |
| 2 | 1 | Contagion | $4,794 | - | 6 | - | $799 | $12,695 | 2 | Warner Bros. | false | false |
| 3 | 3 | Rise of the Planet of the Apes | $3,349 | -9% | 2 | - | $1,674 | $30,801 | 5 | 20th Century Fox International | false | false |
| 4 | 7 | The Smurfs | $1,656 | +2.9% | 4 | +1 | $414 | $36,718 | 5 | Sony Pictures Releasing | false | false |
| 5 | 2 | Bad Teacher | $1,627 | -59.9% | 5 | -1 | $325 | $7,706 | 2 | Sony Pictures Releasing | false | false |
| 6 | 6 | Cowboys & Aliens | $1,287 | -29.8% | 4 | -2 | $321 | $31,928 | 4 | United International Pictures | false | false |
| 7 | 5 | Zookeeper | $764 | -64.7% | 4 | -1 | $191 | $11,612 | 3 | Sony Pictures Releasing | false | false |
| 8 | - | Bridesmaids | $695 | - | 1 | - | $695 | $23,461 | 8 | United International Pictures | false | false |
| 9 | 9 | Captain America: The First Avenger | $597 | +33.3% | 3 | - | $199 | $41,927 | 6 | United International Pictures | false | false |
| 10 | 10 | Horrible Bosses | $560 | +26.1% | 3 | - | $186 | $39,792 | 9 | Warner Bros. | false | false |
| 11 | 11 | Rio | $402 | -5.9% | 3 | +2 | $134 | $4,318 | 4 | 20th Century Fox International | false | false |
| 12 | 8 | Cars 2 | $356 | -53.1% | 1 | -1 | $356 | $37,295 | 9 | Walt Disney Pictures | false | false |
| 13 | 14 | Mr. Popper's Penguins | $227 | +131.6% | 1 | - | $227 | $3,413 | 7 | 20th Century Fox International | false | false |
| 14 | 12 | Monte Carlo | $143 | -22.3% | 1 | - | $143 | $6,321 | 6 | 20th Century Fox International | false | false |
| 15 | 13 | Harry Potter and the Deathly Hallows: Part 2 | $126 | -23.6% | 1 | -3 | $126 | $110,152 | 10 | Warner Bros. | false | false |
