| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Smurfs | $33,316 | -30.8% | 21 | +3 | $1,586 | $596,020 | 6 | Sony Pictures Releasing | false | false |
| 2 | 2 | Cars 2 | $24,260 | -37.8% | 23 | -1 | $1,054 | $196,368 | 3 | Walt Disney Pictures | false | false |
| 3 | - | Shark Night | $17,912 | - | 8 | - | $2,239 | $17,912 | 1 | N/A | true | false |
| 4 | 3 | The Change-Up | $17,171 | -33.4% | 11 | - | $1,561 | $51,726 | 2 | United International Pictures | false | false |
| 5 | 4 | Conan the Barbarian | $16,375 | -35.7% | 13 | - | $1,259 | $121,069 | 3 | N/A | false | false |
| 6 | 5 | Horrible Bosses | $16,083 | -36.5% | 12 | - | $1,340 | $165,132 | 4 | Warner Bros. | false | false |
| 7 | - | Crazy, Stupid, Love. | $16,060 | - | 9 | - | $1,784 | $16,060 | 1 | Warner Bros. | true | false |
| 8 | 6 | Final Destination 5 | $9,694 | -41.7% | 12 | - | $807 | $35,128 | 2 | Warner Bros. | false | false |
| 9 | 7 | Bad Teacher | $9,473 | -39.6% | 11 | - | $861 | $69,010 | 3 | Sony Pictures Releasing | false | false |
| 10 | - | Zookeeper | $8,731 | - | 8 | - | $1,091 | $8,731 | 1 | Sony Pictures Releasing | true | false |
| 11 | 9 | The Tree of Life | $6,261 | -22.1% | 2 | - | $3,130 | $18,054 | 2 | N/A | false | false |
| 12 | 8 | Harry Potter and the Deathly Hallows: Part 2 | $5,295 | -49.8% | 10 | - | $529 | $836,392 | 9 | Warner Bros. | false | false |
| 13 | - | Don't Be Afraid of the Dark | $5,220 | - | 9 | - | $580 | $5,220 | 1 | N/A | true | false |
| 14 | 12 | Cowboys & Aliens | $4,365 | -36.2% | 12 | - | $363 | $62,174 | 4 | United International Pictures | false | false |
| 15 | 10 | Rise of the Planet of the Apes | $4,015 | -46.2% | 11 | - | $365 | $156,183 | 6 | 20th Century Fox International | false | false |
| 16 | 11 | Scream 4 | $3,012 | -58.2% | 8 | - | $376 | $46,194 | 4 | N/A | false | false |
| 17 | 14 | Monte Carlo | $2,524 | -26.6% | 5 | - | $504 | $48,490 | 5 | 20th Century Fox International | false | false |
| 18 | 16 | Kung Fu Panda 2 | $1,539 | +11.7% | 4 | - | $384 | $557,396 | 15 | United International Pictures | false | false |
| 19 | 13 | Green Lantern | $1,366 | -74.7% | 8 | - | $170 | $82,610 | 5 | Warner Bros. | false | false |
| 20 | 15 | Ironclad | $1,115 | -34.2% | 4 | - | $278 | $23,676 | 5 | N/A | false | false |
| 21 | 17 | Captain America: The First Avenger | $1,088 | -5.2% | 5 | - | $217 | $134,319 | 7 | United International Pictures | false | false |
