| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Smurfs | $41,514 | -16.2% | 12 | - | $3,459 | $368,319 | 4 | Sony Pictures Releasing | false | false |
| 2 | - | Final Destination 5 | $14,323 | - | 10 | - | $1,432 | $17,265 | 1 | Warner Bros. | true | false |
| 3 | 2 | Mr. Popper's Penguins | $7,954 | -25.7% | 6 | - | $1,325 | $33,286 | 2 | 20th Century Fox International | false | false |
| 4 | 4 | Horrible Bosses | $7,081 | -21.6% | 7 | - | $1,011 | $53,567 | 3 | Warner Bros. | false | false |
| 5 | 3 | Zookeeper | $5,741 | -40.6% | 10 | +2 | $574 | $20,770 | 2 | Sony Pictures Releasing | false | false |
| 6 | 6 | Rise of the Planet of the Apes | $4,447 | +16.8% | 6 | - | $741 | $61,562 | 5 | 20th Century Fox International | false | false |
| 7 | - | Larry Crowne | $2,882 | - | 3 | - | $960 | $3,812 | 1 | N/A | true | false |
| 8 | 5 | Harry Potter and the Deathly Hallows: Part 2 | $2,790 | -54.4% | 12 | - | $232 | $288,478 | 8 | Warner Bros. | false | false |
| 9 | 8 | The Hangover Part II | $1,476 | +6.7% | 7 | - | $210 | $332,321 | 15 | Warner Bros. | false | false |
| 10 | 7 | Cowboys & Aliens | $553 | -64.4% | 5 | - | $110 | $18,258 | 4 | United International Pictures | false | false |
| 11 | 13 | The Ages of Love | $457 | +19% | 2 | - | $228 | $34,386 | 15 | N/A | false | false |
| 12 | 9 | Pirates of the Caribbean: On Stranger Tides | $435 | -32.1% | 12 | - | $36 | $407,410 | 16 | Walt Disney Pictures | false | false |
| 13 | 14 | Kung Fu Panda 2 | $408 | +13.6% | 11 | - | $37 | $192,558 | 14 | United International Pictures | false | false |
| 14 | 16 | Captain America: The First Avenger | $395 | +41.1% | 4 | - | $98 | $32,167 | 6 | United International Pictures | false | false |
| 15 | 17 | Winnie the Pooh | $364 | +105.6% | 7 | - | $52 | $21,295 | 9 | Walt Disney Pictures | false | false |
| 16 | 10 | Green Lantern | $292 | -54.3% | 7 | - | $41 | $19,706 | 5 | Warner Bros. | false | false |
| 17 | 20 | Hanna | $238 | +750% | 4 | +2 | $59 | $29,099 | 13 | Sony Pictures Releasing | false | false |
| 18 | 12 | Bridesmaids | $104 | -77.2% | 3 | - | $34 | $42,525 | 11 | United International Pictures | false | false |
| 19 | 11 | Transformers: Dark of the Moon | $86 | -82.7% | 11 | - | $7 | $123,599 | 10 | United International Pictures | false | false |
| 20 | 19 | Something Borrowed | $71 | -15.5% | 3 | - | $23 | $25,202 | 17 | N/A | false | false |
| 21 | 18 | Super 8 | $21 | -86.6% | 4 | - | $5 | $49,233 | 12 | Walt Disney Pictures | false | false |
