| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Final Destination 5 | $4,386,871 | - | 360 | - | $12,185 | $4,386,871 | 1 | Warner Bros. | true | false |
| 2 | 1 | Rise of the Planet of the Apes | $2,636,355 | -28.5% | 640 | +12 | $4,119 | $25,499,465 | 4 | 20th Century Fox International | false | false |
| 3 | 3 | The Smurfs | $2,465,169 | -17.5% | 526 | -13 | $4,686 | $23,415,194 | 5 | Sony Pictures Releasing | false | false |
| 4 | 2 | Cowboys & Aliens | $1,807,153 | -47.5% | 480 | - | $3,764 | $6,010,043 | 2 | Paramount Pictures International | false | false |
| 5 | - | Declaration of War | $1,565,350 | - | 129 | - | $12,134 | $1,606,048 | 1 | Wild Bunch Distribution | true | false |
| 6 | 4 | Captain America: The First Avenger | $1,532,169 | -30.9% | 500 | - | $3,064 | $8,818,329 | 3 | Paramount Pictures International | false | false |
| 7 | 6 | Horrible Bosses | $1,189,000 | -19.4% | 246 | -7 | $4,833 | $5,412,356 | 3 | Warner Bros. | false | false |
| 8 | 5 | You Will Be My Son | $1,181,391 | -38.4% | 327 | +25 | $3,612 | $3,583,978 | 2 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | Cars 2 | $1,086,115 | -22.9% | 585 | -77 | $1,856 | $27,122,725 | 6 | Walt Disney Pictures | false | false |
| 10 | - | R.I.F. | $977,932 | - | 292 | - | $3,349 | $977,932 | 1 | StudioCanal | true | false |
| 11 | 8 | The Skin I Live In | $904,591 | -24.2% | 353 | +3 | $2,562 | $4,354,456 | 3 | N/A | false | false |
| 12 | 9 | Super 8 | $635,382 | -32.9% | 341 | -109 | $1,863 | $13,159,436 | 5 | Paramount Pictures International | false | false |
| 13 | 12 | Harry Potter and the Deathly Hallows: Part 2 | $608,969 | -27.7% | 276 | -138 | $2,206 | $67,311,500 | 8 | Warner Bros. | false | false |
| 14 | 10 | One Day | $604,797 | -35.1% | 195 | -2 | $3,101 | $1,810,572 | 2 | N/A | false | false |
| 15 | 13 | Beloved | $487,089 | -39.4% | 264 | +32 | $1,845 | $1,499,518 | 2 | N/A | false | false |
| 16 | 11 | Green Lantern | $468,542 | -44.6% | 267 | -133 | $1,754 | $7,594,611 | 4 | Warner Bros. | false | false |
| 17 | 14 | Bridesmaids | $427,382 | -33.9% | 177 | -39 | $2,414 | $4,609,169 | 4 | Universal Pictures International (UPI) | false | false |
| 18 | 16 | This Must Be the Place | $294,659 | -42.8% | 51 | -100 | $5,777 | $953,130 | 2 | N/A | false | false |
| 19 | - | Cave of Forgotten Dreams | $202,523 | - | 48 | - | $4,219 | $202,523 | 1 | Metropolitan Filmexport | true | false |
| 20 | 19 | Zookeeper | $195,507 | -35.5% | 133 | -41 | $1,469 | $1,261,944 | 3 | Sony Pictures Releasing | false | false |
| 21 | - | Blackthorn | $178,240 | - | 67 | - | $2,660 | $178,240 | 1 | Bac Films | true | false |
| 22 | 20 | Bad Teacher | $128,867 | -45.9% | 95 | -56 | $1,356 | $8,959,797 | 6 | Sony Pictures Releasing | false | false |
| 23 | - | Neds | $94,889 | - | 41 | - | $2,314 | $94,889 | 1 | N/A | true | false |
| 24 | - | Win Win | $51,958 | - | 30 | - | $1,731 | $56,236 | 1 | 20th Century Fox International | true | false |
