| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: On Stranger Tides | $100,512 | -21.9% | 9 | - | $11,168 | $255,239 | 2 | Walt Disney Pictures | false | false |
| 2 | - | The Hangover Part II | $53,092 | - | 8 | - | $6,636 | $53,092 | 1 | Warner Bros. | true | false |
| 3 | 2 | Fast Five | $38,021 | -22.7% | 10 | - | $3,802 | $287,804 | 4 | United International Pictures | false | false |
| 4 | 3 | Rio | $17,695 | -20% | 8 | - | $2,211 | $174,956 | 5 | 20th Century Fox International | false | false |
| 5 | - | Priest | $15,165 | - | 8 | - | $1,895 | $15,165 | 1 | Sony Pictures Releasing | true | false |
| 6 | 5 | Scream 4 | $14,409 | +12.7% | 5 | -1 | $2,881 | $95,917 | 5 | N/A | false | false |
| 7 | - | Water for Elephants | $11,311 | - | 5 | - | $2,262 | $11,311 | 1 | 20th Century Fox International | true | false |
| 8 | 4 | Thor | $9,955 | -44.8% | 7 | -3 | $1,422 | $149,710 | 5 | United International Pictures | false | false |
| 9 | 8 | The Rite | $4,709 | +13.5% | 3 | -1 | $1,569 | $156,885 | 12 | Warner Bros. | false | false |
| 10 | - | Tomorrow, When the War Began | $4,529 | - | 5 | - | $905 | $4,529 | 1 | N/A | true | false |
| 11 | 16 | Just Go with It | $3,393 | +39.6% | 3 | - | $1,131 | $116,326 | 14 | Sony Pictures Releasing | false | false |
| 12 | 9 | Hall Pass | $1,943 | -46.6% | 2 | - | $971 | $55,813 | 7 | Warner Bros. | false | false |
| 13 | 10 | The Other Woman | $1,744 | -51.4% | 2 | - | $872 | $20,774 | 4 | N/A | false | false |
| 14 | 17 | Hop | $1,727 | -28% | 4 | -1 | $431 | $52,702 | 6 | United International Pictures | false | false |
| 15 | 7 | Paul | $1,425 | -74.2% | 4 | - | $356 | $18,115 | 3 | United International Pictures | false | false |
| 16 | 12 | Unknown | $1,359 | -57% | 1 | - | $1,359 | $129,495 | 10 | Warner Bros. | false | false |
| 17 | 11 | Source Code | $992 | -69.9% | 1 | -1 | $992 | $118,448 | 9 | - | false | false |
| 18 | 6 | Ironclad | $957 | -87.1% | 2 | -4 | $478 | $25,923 | 3 | N/A | false | false |
| 19 | 20 | The Adjustment Bureau | $930 | -17.8% | 4 | -1 | $232 | $65,061 | 7 | United International Pictures | false | false |
| 20 | 19 | No Strings Attached | $735 | -41.8% | 3 | -1 | $245 | $87,432 | 9 | United International Pictures | false | false |
| 21 | 14 | Red Riding Hood | $630 | -76.7% | 1 | -2 | $630 | $32,696 | 6 | Warner Bros. | false | false |
| 22 | 21 | Rango | $591 | +49.6% | 3 | +1 | $197 | $38,395 | 7 | United International Pictures | false | false |
| 23 | 13 | The Lincoln Lawyer | $506 | -81.4% | 1 | -1 | $506 | $60,573 | 6 | N/A | false | false |
| 24 | 15 | Sucker Punch | $441 | -82.2% | 1 | -4 | $441 | $15,635 | 4 | Warner Bros. | false | false |
