| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Battle Los Angeles | $313,947 | -16.6% | 69 | +2 | $4,549 | $906,473 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Hall Pass | $189,993 | - | 40 | - | $4,749 | $189,993 | 1 | Warner Bros. | true | false |
| 3 | 5 | A Turtle's Tale: Sammy's Adventures | $175,171 | +11.4% | 35 | - | $5,004 | $394,237 | 2 | N/A | false | false |
| 4 | 2 | The Rite | $161,337 | -25% | 48 | -7 | $3,361 | $2,416,400 | 5 | Warner Bros. | false | false |
| 5 | 3 | Rango | $141,724 | -18.3% | 58 | -4 | $2,443 | $1,920,038 | 5 | United International Pictures | false | false |
| 6 | 6 | Mars Needs Moms | $119,491 | -11.1% | 45 | +2 | $2,655 | $962,753 | 4 | Walt Disney Pictures | false | false |
| 7 | 4 | Unknown | $103,736 | -34% | 39 | -9 | $2,659 | $707,293 | 3 | Warner Bros. | false | false |
| 8 | - | Julia's Eyes | $64,014 | - | 29 | - | $2,207 | $64,014 | 1 | United International Pictures | true | false |
| 9 | 7 | No Strings Attached | $63,891 | -36.7% | 26 | -8 | $2,457 | $1,654,228 | 6 | United International Pictures | false | false |
| 10 | 8 | Killers | $60,191 | -37.4% | 23 | -5 | $2,617 | $400,997 | 3 | N/A | false | false |
| 11 | - | The Descent: Part 2 | $54,712 | - | 21 | - | $2,605 | $54,712 | 1 | N/A | true | false |
| 12 | 9 | Unstoppable | $30,761 | -57.1% | 18 | -24 | $1,708 | $368,912 | 3 | 20th Century Fox International | false | false |
| 13 | 11 | The King's Speech | $21,501 | -22.5% | 12 | -3 | $1,791 | $516,994 | 6 | N/A | false | false |
| 14 | 10 | I Am Number Four | $20,421 | -36.8% | 25 | -13 | $816 | $740,892 | 5 | Walt Disney Pictures | false | false |
| 15 | 13 | The Kid Who Lies | $17,373 | -22.7% | 9 | -4 | $1,930 | $665,215 | 10 | N/A | false | false |
| 16 | 12 | Gulliver's Travels | $13,553 | -46.4% | 16 | -9 | $847 | $1,691,651 | 6 | 20th Century Fox International | false | false |
| 17 | 14 | The Chronicles of Narnia: The Voyage of the Dawn Treader | $11,330 | -31.3% | 8 | -7 | $1,416 | $2,514,800 | 8 | 20th Century Fox International | false | false |
| 18 | 16 | The Secret in Their Eyes | $6,730 | -22.8% | 2 | -2 | $3,365 | $54,208 | 3 | N/A | false | false |
| 19 | 15 | It's Alive | $5,861 | -43.1% | 6 | -2 | $976 | $103,926 | 4 | N/A | false | false |
| 20 | 21 | Easy A | $2,058 | +131.8% | 4 | +1 | $514 | $180,960 | 5 | Sony Pictures Releasing | false | false |
| 21 | 17 | Splinter | $2,005 | -68.5% | 5 | -5 | $401 | $80,653 | 4 | N/A | false | false |
| 22 | 18 | The Fighter | $1,048 | -83.3% | 3 | -1 | $349 | $181,350 | 6 | N/A | false | false |
