| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Rango | $2,748,504 | - | 296 | - | $9,285 | $2,748,504 | 1 | Paramount Pictures International | true | false |
| 2 | 1 | Hall Pass | $1,482,983 | -26% | 306 | +1 | $4,846 | $4,164,005 | 2 | Warner Bros. | false | false |
| 3 | 2 | The Adjustment Bureau | $1,424,789 | -21.7% | 242 | - | $5,887 | $3,924,880 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | 3 | I Am Number Four | $775,506 | -41.6% | 322 | -19 | $2,408 | $6,230,803 | 3 | Walt Disney Pictures | false | false |
| 5 | 4 | The King's Speech | $755,392 | -30.8% | 237 | -2 | $3,187 | $28,922,957 | 12 | Paramount Pictures International | false | false |
| 6 | 5 | Gnomeo & Juliet | $564,842 | -47.8% | 231 | +5 | $2,445 | $6,000,983 | 4 | Walt Disney Pictures | false | false |
| 7 | - | The Rite | $415,021 | - | 81 | - | $5,123 | $415,021 | 1 | Warner Bros. | true | false |
| 8 | 6 | Unknown | $408,265 | -27.9% | 166 | -29 | $2,459 | $5,025,367 | 4 | Warner Bros. | false | false |
| 9 | 7 | The Girl Who Kicked the Hornet's Nest | $359,220 | -27.6% | 103 | +4 | $3,487 | $1,278,746 | 2 | Rialto Distribution | false | false |
| 10 | 9 | Black Swan | $247,876 | -36.1% | 165 | -24 | $1,502 | $14,247,508 | 8 | 20th Century Fox International | false | false |
| 11 | 8 | No Strings Attached | $219,953 | -43.6% | 124 | -43 | $1,773 | $7,581,329 | 5 | Paramount Pictures International | false | false |
| 12 | 10 | Conviction 2010 Re-release | $215,886 | -44.1% | 177 | -23 | $1,219 | $1,903,291 | 3 | 20th Century Fox International | false | false |
| 13 | 11 | Big Mommas: Like Father, Like Son | $146,910 | -48.9% | 100 | -53 | $1,469 | $2,279,099 | 4 | 20th Century Fox International | false | false |
| 14 | 12 | True Grit | $126,503 | -35.4% | 103 | -15 | $1,228 | $8,161,839 | 7 | Paramount Pictures International | false | false |
| 15 | - | The Company Men | $104,268 | - | 24 | - | $4,344 | $104,268 | 1 | Madman Entertainment | true | false |
| 16 | 13 | 127 Hours | $70,058 | -57% | 78 | -38 | $898 | $3,590,355 | 5 | 20th Century Fox International | false | false |
| 17 | 16 | Inside Job | $68,895 | +18.8% | 9 | +2 | $7,655 | $309,866 | 4 | Sony Pictures Releasing | false | false |
| 18 | 14 | The Way Back | $64,533 | -56.8% | 46 | -80 | $1,402 | $785,527 | 3 | Roadshow Films | false | false |
| 19 | 17 | The Fighter | $51,403 | -10.5% | 58 | +1 | $886 | $6,120,836 | 8 | Roadshow Films | false | false |
| 20 | 15 | Rabbit Hole | $47,291 | -36.8% | 23 | -3 | $2,056 | $579,666 | 4 | Roadshow Films | false | false |
| 21 | - | Kiss Me Again | $14,267 | - | 12 | - | $1,188 | $14,267 | 1 | Sharmill Films | true | false |
| 22 | - | Howl | $13,671 | - | 2 | - | $6,835 | $13,671 | 1 | Madman Entertainment | true | false |
