| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | I Am Number Four | $2,289,909 | - | 340 | - | $6,735 | $3,144,903 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Gnomeo & Juliet | $1,523,688 | -22.5% | 224 | +2 | $6,802 | $3,942,491 | 2 | Walt Disney Pictures | false | false |
| 3 | 2 | Unknown | $1,140,713 | -33.8% | 200 | - | $5,703 | $3,499,763 | 2 | Warner Bros. | false | false |
| 4 | 4 | The King's Speech | $1,039,917 | -9.6% | 225 | +3 | $4,621 | $26,158,327 | 10 | Paramount Pictures International | false | false |
| 5 | 3 | No Strings Attached | $947,291 | -35.1% | 230 | -24 | $4,118 | $6,566,100 | 3 | Paramount Pictures International | false | false |
| 6 | - | Conviction 2010 Re-release | $748,953 | - | 198 | - | $3,782 | $838,145 | 1 | 20th Century Fox International | true | false |
| 7 | 5 | Big Mommas: Like Father, Like Son | $562,017 | -39.4% | 185 | - | $3,037 | $1,691,085 | 2 | 20th Century Fox International | false | false |
| 8 | 6 | Black Swan | $539,497 | -33.2% | 208 | -24 | $2,593 | $13,255,034 | 6 | 20th Century Fox International | false | false |
| 9 | 7 | 127 Hours | $388,630 | -46.8% | 171 | -11 | $2,272 | $3,195,419 | 3 | 20th Century Fox International | false | false |
| 10 | - | The Way Back | $352,427 | - | 128 | - | $2,753 | $366,488 | 1 | Roadshow Films | true | false |
| 11 | 8 | True Grit | $341,390 | -39% | 151 | -50 | $2,260 | $7,662,699 | 5 | Paramount Pictures International | false | false |
| 12 | - | The Girl Who Kicked the Hornet's Nest | $226,158 | - | 83 | - | $2,724 | $226,158 | - | Rialto Distribution | - | false |
| 13 | 9 | Hereafter | $217,077 | -60% | 169 | -27 | $1,284 | $2,473,268 | 3 | Warner Bros. | false | false |
| 14 | 12 | Rabbit Hole | $123,306 | -24.8% | 26 | - | $4,742 | $368,283 | 2 | Roadshow Films | false | false |
| 15 | 11 | The Fighter | $88,781 | -49.2% | 61 | -47 | $1,455 | $5,967,849 | 6 | Roadshow Films | false | false |
| 16 | 10 | Sanctum | $86,553 | -75.9% | 94 | -155 | $920 | $3,846,797 | 4 | Universal Pictures International (UPI) | false | false |
| 17 | - | Certified Copy | $85,067 | - | 7 | - | $12,152 | $196,843 | 2 | Madman Entertainment | false | false |
| 18 | 14 | Yogi Bear | $77,100 | -40.9% | 109 | -48 | $707 | $14,626,263 | 6 | Warner Bros. | false | false |
| 19 | 16 | Burlesque | $61,573 | -50.5% | 70 | -28 | $879 | $7,634,376 | 7 | Sony Pictures Releasing | false | false |
| 20 | 21 | Inside Job | $51,424 | -9.5% | 7 | - | $7,346 | $132,182 | 2 | Sony Pictures Releasing | false | false |
