| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Tangled | $86,802 | - | 17 | - | $5,106 | $103,278 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | - | The Mechanic | $30,535 | - | 6 | - | $5,089 | $30,535 | 1 | Incognito Films | true | false |
| 3 | - | Black Swan | $21,252 | - | 3 | - | $7,084 | $21,252 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | 1 | Burlesque | $12,463 | -38% | 8 | - | $1,557 | $60,084 | 2 | ACME | false | false |
| 5 | 2 | The Tourist | $10,278 | -47.5% | 7 | - | $1,468 | $166,863 | 4 | ACME | false | false |
| 6 | 7 | The King's Speech | $7,982 | -6.7% | 2 | - | $3,991 | $21,994 | 2 | ACME | false | false |
| 7 | 3 | The Green Hornet | $6,744 | -56% | 8 | - | $843 | $76,400 | 3 | ACME | false | false |
| 8 | 4 | Life as We Know It | $6,481 | -47.5% | 5 | - | $1,296 | $61,345 | 3 | ACME | false | false |
| 9 | 6 | Love & Other Drugs | $5,349 | -38.6% | 4 | - | $1,337 | $80,143 | 4 | Universal Pictures International (UPI) | false | false |
| 10 | 5 | Megamind | $4,289 | -56.5% | 10 | +1 | $428 | $239,762 | 7 | Universal Pictures International (UPI) | false | false |
| 11 | 10 | The Chronicles of Narnia: The Voyage of the Dawn Treader | $3,294 | -21.7% | 13 | +5 | $253 | $242,450 | 8 | Universal Pictures International (UPI) | false | false |
| 12 | 9 | The Dilemma | $2,501 | -51.5% | 3 | - | $833 | $13,435 | 2 | Universal Pictures International (UPI) | false | false |
| 13 | 8 | Rabbit Hole | $1,086 | -81.9% | 4 | - | $271 | $24,779 | 3 | Incognito Films | false | false |
| 14 | 18 | Heartbreaker | $803 | -2.7% | 1 | - | $803 | $22,402 | 7 | Filmarti | false | false |
| 15 | 11 | Little Fockers | $680 | -81.2% | 2 | -3 | $340 | $120,952 | 6 | Universal Pictures International (UPI) | false | false |
| 16 | 20 | A Rational Solution | $407 | -29.8% | 1 | - | $407 | $1,944 | 3 | - | false | false |
| 17 | 13 | Tucker and Dale vs Evil | $377 | -81.2% | 1 | -2 | $377 | $56,449 | 7 | Incognito Films | false | false |
| 18 | 27 | Babies | $134 | +5.5% | 1 | - | $134 | $6,306 | 10 | - | false | false |
| 19 | 25 | Toy Story 3 | $99 | -51.2% | 1 | - | $99 | $221,290 | 30 | Universal Pictures International (UPI) | false | false |
| 20 | - | Scott Pilgrim vs. the World | $43 | - | 1 | - | $43 | $4,806 | 5 | Universal Pictures International (UPI) | false | false |
| 21 | 12 | Tron: Legacy | $28 | -99.1% | 8 | +1 | $3 | $145,989 | 6 | Universal Pictures International (UPI) | false | false |
| 22 | 31 | The Last Airbender | $23 | -45.2% | 1 | - | $23 | $156,754 | 24 | Universal Pictures International (UPI) | false | false |
| 23 | - | Knight and Day 2010 Re-release | $14 | - | 1 | - | $14 | $107,139 | 29 | Universal Pictures International (UPI) | false | false |
| 24 | 29 | Despicable Me | $5 | -93.1% | 1 | - | $5 | $499,983 | 16 | Universal Pictures International (UPI) | false | false |
