| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Yogi Bear | $3,814,586 | - | 381 | - | $10,012 | $3,854,291 | - | Warner Bros. | - | false |
| 2 | 1 | Tangled | $3,325,245 | -42.4% | 432 | -30 | $7,697 | $13,211,626 | 2 | Walt Disney Pictures | false | false |
| 3 | - | Burlesque | $1,850,693 | - | 204 | - | $9,072 | $1,892,323 | 1 | Sony Pictures Releasing | true | false |
| 4 | 4 | The King's Speech | $1,794,101 | -17.5% | 117 | +10 | $15,334 | $12,236,361 | 4 | Paramount Pictures International | false | false |
| 5 | - | The Dilemma | $1,411,988 | - | 227 | - | $6,220 | $1,411,988 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 3 | Unstoppable | $1,220,937 | -45.6% | 268 | -12 | $4,555 | $4,450,133 | 2 | 20th Century Fox International | false | false |
| 7 | 2 | Little Fockers | $1,125,538 | -50.4% | 312 | -41 | $3,607 | $17,354,899 | 4 | Paramount Pictures International | false | false |
| 8 | 6 | Gulliver's Travels | $1,057,103 | -45.7% | 370 | -33 | $2,857 | $13,888,817 | 4 | 20th Century Fox International | false | false |
| 9 | 5 | Morning Glory | $1,015,416 | -50.4% | 243 | -1 | $4,178 | $4,076,377 | 2 | Paramount Pictures International | false | false |
| 10 | 7 | The Tourist | $684,202 | -51.8% | 248 | -22 | $2,758 | $10,220,836 | 4 | Sony Pictures Releasing | false | false |
| 11 | 8 | Tron: Legacy | $465,125 | -52.4% | 141 | -221 | $3,298 | $13,501,115 | 5 | Walt Disney Pictures | false | false |
| 12 | 11 | Harry Potter and the Deathly Hallows: Part 1 | $219,764 | -54% | 96 | -81 | $2,289 | $41,091,535 | 9 | Warner Bros. | false | false |
| 13 | 9 | Megamind | $198,105 | -69.8% | 167 | -150 | $1,186 | $15,330,934 | 6 | Paramount Pictures International | false | false |
| 14 | 10 | Love & Other Drugs | $195,380 | -65.6% | 96 | -111 | $2,035 | $7,568,103 | 5 | 20th Century Fox International | false | false |
| 15 | - | Crazy Mad Lover | $161,285 | - | 13 | - | $12,406 | $161,285 | 1 | Eros Worldwide | true | false |
| 16 | 13 | Blue Valentine | $119,735 | -25.8% | 27 | +4 | $4,434 | $872,817 | 3 | Palace Films | false | false |
| 17 | 14 | Sarah's Key | $111,606 | -28% | 29 | +2 | $3,848 | $865,981 | 4 | Madman Entertainment | false | false |
| 18 | 12 | The Chronicles of Narnia: The Voyage of the Dawn Treader | $81,341 | -71.6% | 76 | -141 | $1,070 | $12,501,816 | 7 | 20th Century Fox International | false | false |
| 19 | 15 | Heartbreaker | $51,308 | -44% | 24 | -1 | $2,137 | $551,652 | 4 | Hopscotch Films | false | false |
| 20 | - | Desert Flower 2009 Re-release | $50,408 | - | 2 | - | $25,204 | $89,766 | 6 | Madman Entertainment | false | false |
