| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Tron: Legacy | $3,319,143 | - | 434 | - | $7,647 | $3,319,143 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Megamind | $2,008,378 | -17.5% | 418 | -7 | $4,804 | $7,080,745 | 2 | Paramount Pictures International | false | false |
| 3 | - | Love & Other Drugs | $1,905,224 | - | 236 | - | $8,072 | $1,995,038 | 1 | 20th Century Fox International | true | false |
| 4 | 3 | The Chronicles of Narnia: The Voyage of the Dawn Treader | $1,266,503 | -30.3% | 416 | -60 | $3,044 | $7,941,410 | 3 | 20th Century Fox International | false | false |
| 5 | 2 | Harry Potter and the Deathly Hallows: Part 1 | $1,265,690 | -37.4% | 461 | -112 | $2,745 | $36,252,420 | 5 | Warner Bros. | false | false |
| 6 | 4 | Due Date | $707,199 | -44.2% | 261 | -27 | $2,709 | $8,923,069 | 4 | Warner Bros. | false | false |
| 7 | - | The King's Speech | $453,951 | - | 93 | - | $4,881 | $458,276 | - | Paramount Pictures International | - | false |
| 8 | 5 | Devil | $153,293 | -57.4% | 113 | -34 | $1,356 | $1,427,213 | 3 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | The Social Network | $139,635 | -41.3% | 92 | -11 | $1,517 | $11,299,152 | 8 | Sony Pictures Releasing | false | false |
| 10 | 6 | Fair Game | $130,074 | -60.2% | 94 | -43 | $1,383 | $2,135,473 | 4 | Hoyts Distribution | false | false |
| 11 | 8 | RED | $72,318 | -47.3% | 57 | -11 | $1,268 | $7,897,356 | 8 | Icon Film Distribution | false | false |
| 12 | - | Somewhere | $53,429 | - | 42 | - | $1,272 | $53,429 | 1 | Universal Pictures International (UPI) | true | false |
| 13 | 9 | The Last Exorcism | $28,162 | -73.4% | 24 | -67 | $1,173 | $1,206,443 | 4 | Hopscotch Films | false | false |
| 14 | 13 | Made in Dagenham | $24,434 | -38.7% | 26 | -14 | $939 | $1,367,962 | 8 | Paramount Pictures International | false | false |
| 15 | 14 | Life as We Know It | $23,761 | -36% | 20 | -9 | $1,188 | $7,296,251 | 9 | Warner Bros. | false | false |
| 16 | 10 | Jackass 3D | $20,620 | -80.4% | 16 | -37 | $1,288 | $9,881,627 | 7 | Paramount Pictures International | false | false |
| 17 | 11 | No Problem | $19,796 | -69.9% | 16 | -1 | $1,237 | $114,256 | 2 | Eros Worldwide | false | false |
| 18 | - | Heartbreaker | $19,257 | - | 19 | - | $1,013 | $39,178 | - | Hopscotch Films | - | false |
| 19 | 12 | The American | $18,665 | -60% | 25 | -7 | $746 | $1,156,646 | 6 | Universal Pictures International (UPI) | false | false |
